Daily Papers

Machine learning systems in fraud detection, credit scoring, and clinical risk assessment operate under delayed ground truth: outcome labels arrive days to months after the decision they evaluate. During this blind period, governance evidence degrades through mechanisms that neither drift detection methods nor governance frameworks adequately address. This paper formalizes an evidence sufficiency model with four dimensions (completeness, freshness, reliability, representativeness) and a decision-readiness gate that quantifies how label latency degrades evidence quality. The model maps three drift types to dimension-specific degradation trajectories. A complementary proxy indicator framework comprising seven measurement categories estimates sufficiency degradation without labels, with explicit coverage mapping and characterized blind spots per drift type. Evaluation on the IEEE-CIS Fraud Detection dataset (~590K transactions) with controlled drift injection shows that composite proxy monitoring detects covariate and mixed drift with 100% detection rate, while concept drift without feature change remains undetected -- consistent with the theoretical impossibility of unsupervised detection when P(X) is unchanged. Blind period simulation confirms monotone sufficiency degradation, with concept drift degrading fastest (S=0.242 at day 60 vs 0.418 for no-drift). The framework contributes a governance sufficiency monitoring instrument; its value lies in translating drift signals into auditable sufficiency assessments with characterized blind spots. Mapping sufficiency levels to governance actions requires deployment-specific calibration beyond this study's scope.

Fake news detection becomes particularly challenging in real-time scenarios, where emerging events often lack sufficient supporting evidence. Existing approaches often rely heavily on external evidence and therefore struggle to generalize under evidence scarcity. To address this issue, we propose Evaluation-Aware Selection of Experts (EASE), a novel framework for real-time fake news detection that dynamically adapts its decision-making process according to the assessed sufficiency of available evidence. EASE introduces a sequential evaluation mechanism comprising three independent perspectives: (1) Evidence-based evaluation, which assesses evidence and incorporates it into decision-making only when the evidence is sufficiently supportive; (2) Reasoning-based evaluation, which leverages the world knowledge of large language models (LLMs) and applies them only when their reliability is adequately established; and (3) Sentiment-based fallback, which integrates sentiment cues when neither evidence nor reasoning is reliable. To enhance the accuracy of evaluation processes, EASE employs instruction tuning with pseudo labels to guide each evaluator in justifying its perspective-specific knowledge through interpretable reasoning. Furthermore, the expert modules integrate the evaluators' justified assessments with the news content to enable evaluation-aware decision-making, thereby enhancing overall detection accuracy. Moreover, we introduce RealTimeNews-25, a new benchmark comprising recent news for evaluating model generalization on emerging news with limited evidence. Extensive experiments demonstrate that EASE not only achieves state-of-the-art performance across multiple benchmarks, but also significantly improves generalization to real-time news. The code and dataset are available: https://github.com/wgyhhhh/EASE.

Retrieval-Augmented Generation (RAG) integrates external knowledge to enhance Large Language Models (LLMs), yet systems remain susceptible to two critical flaws: providing correct answers without explicit grounded evidence and producing fabricated responses when the retrieved context is insufficient. While prior research has addressed these issues independently, a unified framework that integrates evidence-based grounding and reliable abstention is currently lacking. In this paper, we propose GRACE, a reinforcement-learning framework that simultaneously mitigates both types of flaws. GRACE employs a data construction method that utilizes heterogeneous retrievers to generate diverse training samples without manual annotation. A multi-stage gated reward function is then employed to train the model to assess evidence sufficiency, extract key supporting evidence, and provide answers or explicitly abstain. Experimental results on two benchmarks demonstrate that GRACE achieves state-of-the-art overall accuracy and strikes a favorable balance between accurate response and rejection, while requiring only 10% of the annotation costs of prior methods. Our code is available at https://github.com/YiboZhao624/Grace..

Reasoning over ultra-long documents requires synthesizing sparse evidence scattered across distant segments under strict memory constraints. While streaming agents enable scalable processing, their passive memory update strategy often fails to preserve low-salience bridging evidence required for multi-hop reasoning. We propose InfMem, a control-centric agent that instantiates System-2-style control via a PreThink-Retrieve-Write protocol. InfMem actively monitors evidence sufficiency, performs targeted in-document retrieval, and applies evidence-aware joint compression to update a bounded memory. To ensure reliable control, we introduce a practical SFT-to-RL training recipe that aligns retrieval, writing, and stopping decisions with end-task correctness. On ultra-long QA benchmarks from 32k to 1M tokens, InfMem consistently outperforms MemAgent across backbones. Specifically, InfMem improves average absolute accuracy by +10.17, +11.84, and +8.23 points on Qwen3-1.7B, Qwen3-4B, and Qwen2.5-7B, respectively, while reducing inference time by 3.9times on average (up to 5.1times) via adaptive early stopping.

Graph Retrieval-Augmented Generation (Graph-RAG) enhances multihop question answering by organizing corpora into knowledge graphs and routing evidence through relational structure. However, practical deployments face two persistent bottlenecks: (i) mixed-difficulty workloads where one-size-fits-all retrieval either wastes cost on easy queries or fails on hard multihop cases, and (ii) extraction loss, where graph abstraction omits fine-grained qualifiers that remain only in source text. We present A2RAG, an adaptive-and-agentic GraphRAG framework for cost-aware and reliable reasoning. A2RAG couples an adaptive controller that verifies evidence sufficiency and triggers targeted refinement only when necessary, with an agentic retriever that progressively escalates retrieval effort and maps graph signals back to provenance text to remain robust under extraction loss and incomplete graphs. Experiments on HotpotQA and 2WikiMultiHopQA demonstrate that A2RAG achieves +9.9/+11.8 absolute gains in Recall@2, while cutting token consumption and end-to-end latency by about 50% relative to iterative multihop baselines.

Time-aware dense audio captioning (TDAC) aims to generate multiple fine-grained attributes (dense) of the audio with precise time boundaries (time-aware). Existing methods struggle to achieve these two goals and mainly rely on supervised fine-tuning, yielding sub-optimal performance. While reinforcement learning (RL) shows promise, applying it to TDAC faces two main challenges: (1) existing rewards are too coarse to supervise multi-event, multi-attribute, and multi-relation descriptions in a fine-grained manner; and (2) temporal supervision is difficult for free-form captions, where flexible event-time expressions make reliable event-time correspondence challenging. To address these challenges, we propose AudioMap, a novel RL-based TDAC framework, which shifts to a unified cloze-and-choice reward paradigm. Specifically, we introduce the Evidence Sufficiency Reward (ESR) with an asymmetric hierarchical scoring mechanism to promote fine-grained accuracy and descriptive richness across diverse acoustic dimensions. Furthermore, we design the Event-Conditioned Temporal Reward (ECTR) to structurally bind timestamps to event semantics via temporal IoU, accompanied by a dual-curriculum learning strategy to facilitate the training process. Finally, to support this task, we construct the first time-aware fine-grained audio captioning dataset, AudioMapCap-44K, which contains 44K carefully annotated captions. Extensive experiments across diverse benchmarks show that AudioMap achieves state-of-the-art (SOTA) performance among open-source models and delivers competitive or superior results relative to proprietary models. Project page and release updates are available at https://github.com/ryysayhi/AudioMap.

When automated decision systems fail, organizations frequently discover that formally compliant governance infrastructure cannot reconstruct what happened or why. This paper synthesizes an operational governance evidence framework -- structural accountability collapse diagnostics, decision trace schemas, evidence sufficiency measurement, and label-free monitoring -- into an integrated chain and analytically assesses its transferability across four decision system architectures. The cross-architecture comparison reveals a governance coverage gradient: deterministic rule engines achieve full DES-property fillability, hybrid ML+rules systems achieve partial fillability, classical ML systems achieve only minimal fillability, and agentic AI systems encounter structural breaks. We introduce the cascade of uncertainty, showing how governance failures propagate through serial dependencies between framework layers. For agentic systems, we identify three structural breaks -- decision diffusion, evidence fragmentation, and responsibility ambiguity -- and propose corresponding analytical extensions. Four propositions formalize the gradient, cascade compounding, delegation-depth effects, and extension sufficiency, establishing boundary conditions for the framework's valid operating envelope.

Integrating web search tools has significantly extended the capability of LLMs to address open-world, real-time, and long-tail problems. However, evaluating these Search Agents presents formidable challenges. First, constructing high-quality deep search benchmarks is prohibitively expensive, while unverified synthetic data often suffers from unreliable sources. Second, static benchmarks face dynamic obsolescence: as internet information evolves, complex queries requiring deep research often degrade into simple retrieval tasks due to increased popularity, and ground truths become outdated due to temporal shifts. Third, attribution ambiguity confounds evaluation, as an agent's performance is often dominated by its parametric memory rather than its actual search and reasoning capabilities. Finally, reliance on specific commercial search engines introduces variability that hampers reproducibility. To address these issues, we propose a novel framework, Mind-ParaWorld, for evaluating Search Agents in a Parallel World. Specifically, MPW samples real-world entity names to synthesize future scenarios and questions situated beyond the model's knowledge cutoff. A ParaWorld Law Model then constructs a set of indivisible Atomic Facts and a unique ground-truth for each question. During evaluation, instead of retrieving real-world results, the agent interacts with a ParaWorld Engine Model that dynamically generates SERPs grounded in these inviolable Atomic Facts. We release MPW-Bench, an interactive benchmark spanning 19 domains with 1,608 instances. Experiments across three evaluation settings show that, while search agents are strong at evidence synthesis given complete information, their performance is limited not only by evidence collection and coverage in unfamiliar search environments, but also by unreliable evidence sufficiency judgment and when-to-stop decisions-bottlenecks.

Long-term conversational memory requires retrieving evidence scattered across multiple sessions, yet single-pass retrieval fails on temporal and multi-hop questions. Existing iterative methods refine queries via generated content or document-level signals, but none explicitly diagnoses the evidence gap, namely what is missing from the accumulated retrieval set, leaving query refinement untargeted. We present EviMem, combining IRIS (Iterative Retrieval via Insufficiency Signals), a closed-loop framework that detects evidence gaps through sufficiency evaluation, diagnoses what is missing, and drives targeted query refinement, with LaceMem (Layered Architecture for Conversational Evidence Memory), a coarse-to-fine memory hierarchy supporting fine-grained gap diagnosis. On LoCoMo, EviMem improves Judge Accuracy over MIRIX on temporal (73.3% to 81.6%) and multi-hop (65.9% to 85.2%) questions at 4.5x lower latency. Code: https://github.com/AIGeeksGroup/EviMem.

Long video understanding (LVU) is challenging because answering real-world queries often depends on sparse, temporally dispersed cues buried in hours of mostly redundant and irrelevant content. While agentic pipelines improve video reasoning capabilities, prevailing frameworks rely on a query-agnostic captioner to perceive video information, which wastes computation on irrelevant content and blurs fine-grained temporal and spatial information. Motivated by active perception theory, we argue that LVU agents should actively decide what, when, and where to observe, and continuously assess whether the current observation is sufficient to answer the query. We present Active Video Perception (AVP), an evidence-seeking framework that treats the video as an interactive environment and acquires compact, queryrelevant evidence directly from pixels. Concretely, AVP runs an iterative plan-observe-reflect process with MLLM agents. In each round, a planner proposes targeted video interactions, an observer executes them to extract time-stamped evidence, and a reflector evaluates the sufficiency of the evidence for the query, either halting with an answer or triggering further observation. Across five LVU benchmarks, AVP achieves highest performance with significant improvements. Notably, AVP outperforms the best agentic method by 5.7% in average accuracy while only requires 18.4% inference time and 12.4% input tokens.

Multimodal Large Language Models (MLLMs) have shown remarkable progress in single-image perception, yet their ability to reason about complex cross-view human-centric scenes remains largely unverified. Current multi-view benchmarks evaluate models using a fixed "bag of frames" and thus conflate a model's robustness to visual distraction with its genuine ability to fuse fragmented cross-view evidence. To address this issue, we introduce SSMNBench, a diagnostic benchmark comprising 3,300 curated QA pairs for cross-view human and human-object understanding. SSMNBench uniquely categorizes tasks into Single-View Sufficiency (SVS) and Multi-View Necessity (MVN). By systematically perturbing view availability across 17 state-of-the-art MLLMs, critical limitations are revealed: models suffer from severe "distraction degradation" when presented with redundant views (SVS), and fail to integrate fragmented geometric evidence across cameras (MVN). Our evaluations demonstrate that modern MLLMs rely on multiple single-image semantic averaging and view preference rather than genuine cross-view synthesis. By exposing these fundamental vulnerabilities, SSMNBench provides a rigorous diagnostic framework to drive the advancement of future cross-view-aware multimodal architectures. The code is available at: https://github.com/gtc-gh/SSMNBench{SSMNBench}

Textual claims are often accompanied by images to enhance their credibility and spread on social media, but this also raises concerns about the spread of misinformation. Existing datasets for automated verification of image-text claims remain limited, as they often consist of synthetic claims and lack evidence annotations to capture the reasoning behind the verdict. In this work, we introduce AVerImaTeC, a dataset consisting of 1,297 real-world image-text claims. Each claim is annotated with question-answer (QA) pairs containing evidence from the web, reflecting a decomposed reasoning regarding the verdict. We mitigate common challenges in fact-checking datasets such as contextual dependence, temporal leakage, and evidence insufficiency, via claim normalization, temporally constrained evidence annotation, and a two-stage sufficiency check. We assess the consistency of the annotation in AVerImaTeC via inter-annotator studies, achieving a kappa=0.742 on verdicts and 74.7% consistency on QA pairs. We also propose a novel evaluation method for evidence retrieval and conduct extensive experiments to establish baselines for verifying image-text claims using open-web evidence.

Multimodal representation learning is a cornerstone of modern AI. By encoding multimodal queries and targets into vectors, it powers industrial search and recommendation and underpins modern agents. Real-world platforms with complex modalities and massive-scale content, such as Douyin, Xiaohongshu, and YouTube, demand both efficiency under billion-scale indexing and fine-grained discrimination for hard matching. Existing MLLM embedding models rarely satisfy both. Contrastive models are efficient but rely on pair-level supervision too coarse for fine-grained distinctions, while CoT-based models improve discrimination through explicit generation impractical to serve online. We present Douyin Multimodal Embedding (DME), a model trained in two stages to combine both strengths. Stage 1 performs large-scale contrastive pre-training that establishes a unified multimodal embedding space with broad modality and task coverage. Stage 2 supplements semantic sufficiency, the property that an embedding is grounded in retrieval-relevant evidence and preserves fine-grained counterpart-side semantics, via two mechanisms. Evidence-Grounded Typed Latent Reasoning organizes retrieval evidence through hidden-space latent reasoning, and Cross-Conditional Reconstruction enforces counterpart-side semantics through cross-directional autoregressive reconstruction. Both act only during training and add only marginal query-side overhead, so DME serves as efficiently as a standard contrastive encoder. On MMEB-v2, DME reaches state-of-the-art results at comparable scales for its 2B and 9B variants (74.8 and 78.4), with especially strong video and visual-document tasks. In production, DME delivers a 2.92% relative gain on Douyin's in-house offline evaluation set, is deployed across Douyin scenarios such as generative, image, and AI search, and yields a 0.1% Lifetime (LT) gain in online A/B testing on Douyin search.

Large Reasoning Models (LRMs) improve performance by generating explicit intermediate reasoning traces through increased test-time compute, yet the assumption that longer reasoning is consistently beneficial remains under-examined. While recent evidence shows that additional reasoning can lead models to overthink, we ask: "Once a model has reached the correct answer, does further reasoning refine the solution, or deviate from it?" To study the dynamics after correctness, we introduce a prefix-level trajectory evaluation protocol grounded in reasoning sufficiency, defining the minimum reasoning budget required for a model to first generate the correct answer. This allows us to disentangle verbose overthinking, where additional reasoning is redundant but harmless, from harmful overthinking, where continued reasoning destabilizes an already-correct trajectory. Starting from multimodal benchmarks, we find that many instances considered reasoning-intensive require surprisingly little reasoning. Moreover, stopping at the first correct prefix improves accuracy over standard reasoning up to 21%, revealing that current models are limited not only by their ability to reason, but also by their inability to stop at the right time. Furthermore, while common efficiency strategies like early stopping substantially reduce verbose overthinking (up to 50%), they fail to mitigate harmful overthinking. Failure analysis reveals that correctness deviations are mainly driven by logical drift and visual reinterpretation. Finally, we show that our findings generalize to language-only reasoning benchmarks, highlighting harmful overthinking as a broader reliability risk. Code available at https://simonecaldarella.github.io/thinking-past-the-answer.

Long-horizon agents often compress interaction histories into write-time summaries. This creates a fundamental write-before-query barrier: compression decisions are made before the system knows what a future query will hinge on. As a result, summaries can cause unverifiable omissions -- decisive constraints (e.g., allergies) may be dropped, leaving the agent unable to justify an answer with traceable evidence. Retaining raw logs restores an authoritative source of truth, but grounding on raw logs by default is expensive: many queries are answerable from summaries, yet raw grounding still requires processing far longer contexts, inflating token consumption and latency. We propose TierMem, a provenance-linked framework that casts retrieval as an inference-time evidence allocation problem. TierMem uses a two-tier memory hierarchy to answer with the cheapest sufficient evidence: it queries a fast summary index by default, and a runtime sufficiency router Escalates to an immutable raw-log store only when summary evidence is insufficient. TierMem then writes back verified findings as new summary units linked to their raw sources. On LoCoMo, TierMem achieves 0.851 accuracy (vs.0.873 raw-only) while reducing input tokens by 54.1\% and latency by 60.7%.

Knowledge graph question answering (KGQA) aims to answer natural language questions using knowledge graphs. Recent research leverages large language models (LLMs) to enhance KGQA reasoning, but faces limitations: retrieval-based methods are constrained by the quality of retrieved information, while agent-based methods rely heavily on proprietary LLMs. To address these limitations, we propose Retrieval-Judgment-Exploration (RJE), a framework that retrieves refined reasoning paths, evaluates their sufficiency, and conditionally explores additional evidence. Moreover, RJE introduces specialized auxiliary modules enabling small-sized LLMs to perform effectively: Reasoning Path Ranking, Question Decomposition, and Retriever-assisted Exploration. Experiments show that our approach with proprietary LLMs (such as GPT-4o-mini) outperforms existing baselines while enabling small open-source LLMs (such as 3B and 8B parameters) to achieve competitive results without fine-tuning LLMs. Additionally, RJE substantially reduces the number of LLM calls and token usage compared to agent-based methods, yielding significant efficiency improvements.

Retrieval-Augmented Generation (RAG) and Graph-based RAG has become the important paradigm for enhancing Large Language Models (LLMs) with external knowledge. However, existing approaches face a fundamental trade-off. While graph-based methods are inherently dependent on high-quality graph structures, they face significant practical constraints: manually constructed knowledge graphs are prohibitively expensive to scale, while automatically extracted graphs from corpora are limited by the performance of the underlying LLM extractors, especially when using smaller, local-deployed models. This paper presents Think-on-Graph 3.0 (ToG-3), a novel framework that introduces Multi-Agent Context Evolution and Retrieval (MACER) mechanism to overcome these limitations. Our core innovation is the dynamic construction and refinement of a Chunk-Triplets-Community heterogeneous graph index, which pioneeringly incorporates a dual-evolution mechanism of Evolving Query and Evolving Sub-Graph for precise evidence retrieval. This approach addresses a critical limitation of prior Graph-based RAG methods, which typically construct a static graph index in a single pass without adapting to the actual query. A multi-agent system, comprising Constructor, Retriever, Reflector, and Responser agents, collaboratively engages in an iterative process of evidence retrieval, answer generation, sufficiency reflection, and, crucially, evolving query and subgraph. This dual-evolving multi-agent system allows ToG-3 to adaptively build a targeted graph index during reasoning, mitigating the inherent drawbacks of static, one-time graph construction and enabling deep, precise reasoning even with lightweight LLMs. Extensive experiments demonstrate that ToG-3 outperforms compared baselines on both deep and broad reasoning benchmarks, and ablation studies confirm the efficacy of the components of MACER framework.

Despite rapid progress in Multimodal Large Language Models (MLLMs), visual spatial reasoning remains unreliable when correct answers depend on how a scene would appear under unseen or alternative viewpoints. Recent work addresses this by augmenting reasoning with world models for visual imagination, but questions such as when imagination is actually necessary, how much of it is beneficial, and when it becomes harmful, remain poorly understood. In practice, indiscriminate imagination can increase computation and even degrade performance by introducing misleading evidence. In this work, we present an in-depth analysis of test-time visual imagination as a controllable resource for spatial reasoning. We study when static visual evidence is sufficient, when imagination improves reasoning, and how excessive or unnecessary imagination affects accuracy and efficiency. To support this analysis, we introduce AVIC, an adaptive test-time framework with world models that explicitly reasons about the sufficiency of current visual evidence before selectively invoking and scaling visual imagination. Across spatial reasoning benchmarks (SAT, MMSI) and an embodied navigation benchmark (R2R), our results reveal clear scenarios where imagination is critical, marginal, or detrimental, and show that selective control can match or outperform fixed imagination strategies with substantially fewer world-model calls and language tokens. Overall, our findings highlight the importance of analyzing and controlling test-time imagination for efficient and reliable spatial reasoning.

AI systems increasingly retrieve from records that revise themselves: issue threads, encyclopedic histories, policy logs, and long conversations. The challenge is not only finding relevant evidence, but deciding which claims remain in force, which were superseded, and when to abstain. Structured memories promise to solve this with typed edges, temporal updates, and conflict status, yet evaluations often change mechanism and prompt presentation together. We study this as Evidence-State Revision, comparing flat retrieval, coarse edge invalidation, and fine-grained RevisionLedger on 2,907 high-agreement questions from GitHub, multi-repo issue histories, Wikipedia, and DyKnow-style temporal streams. A render-matched control (same layout, deprecation disabled) reveals the central confound: when a value is changed and later restored, RevisionLedger appears to beat a flat baseline by +0.182, but almost all the gain comes from easier presentation; the fine-grained mechanism residual is indistinguishable from zero (+0.021 to +0.025 across two judge families). After presentation is controlled, coarse invalidation is the only mechanism that pays for current-state queries, beating the fine ledger by 0.084; the same query-sufficiency principle says provenance mainly needs retained invalidated evidence, not richer typing. Memory evaluations should hold render fixed, and deprecation-aware systems should deploy the coarsest retained state that covers their queries.

Triple-based Iterative Retrieval-Augmented Generation (iRAG) mitigates document-level noise for multi-hop question answering. However, existing methods still face limitations: (i) greedy single-path expansion, which propagates early errors and fails to capture parallel evidence from different reasoning branches, and (ii) granularity-demand mismatch, where a single evidence representation struggles to balance noise control with contextual sufficiency. In this paper, we propose the Construction-Integration Retrieval and Adaptive Generation model, CIRAG. It introduces an Iterative Construction-Integration module that constructs candidate triples and history-conditionally integrates them to distill core triples and generate the next-hop query. This module mitigates the greedy trap by preserving multiple plausible evidence chains. Besides, we propose an Adaptive Cascaded Multi-Granularity Generation module that progressively expands contextual evidence based on the problem requirements, from triples to supporting sentences and full passages. Moreover, we introduce Trajectory Distillation, which distills the teacher model's integration policy into a lightweight student, enabling efficient and reliable long-horizon reasoning. Extensive experiments demonstrate that CIRAG achieves superior performance compared to existing iRAG methods.

Red-team evaluations of AI models support some claims and not others, and the boundary between the two is calculable rather than merely a matter of judgment. We define the evidential ceiling of an evaluation as the largest factor by which one result can move belief under a fixed testing budget, derive it in closed form for the benchmark null result, and use it to locate that boundary exactly. We find that above a calculable harm rate, a benchmark of modest size certifies a category to a stated evidentiary standard, and a clean sheet is then the stronger of the two possible observations, outweighing a single reproduced failure. Below that rate, no passive benchmark of feasible size provides the specified evidence of safety under the fixed scoring rule and approximately independent trial structure. The crossing between the two regimes has a closed form. The bound is not specific to benchmarks: written in terms of a procedure's hypothesis conditioned elicitation rates, it covers adaptive and automated red teaming as well, and shows that discrimination between the hypotheses rather than attack success is what determines evidential worth. Auditing eight evaluation suites against the boundary, we find that current benchmarks are adequate for high-frequency harm categories and several orders of magnitude short for rare, catastrophic ones. Safety benchmarks are not uninformative. They are informative about a specific and computable set of propositions, and the discipline they need is to state which.

Evidence-grounded reasoning requires more than attaching retrieved text to a prediction: a model should make decisions that depend on whether the provided evidence supports the target claim. In practice, this often fails because supervision is weak, evidence is only loosely tied to the claim, and evaluation does not test evidence dependence directly. We introduce case-grounded evidence verification, a general framework in which a model receives a local case context, external evidence, and a structured claim, and must decide whether the evidence supports the claim for that case. Our key contribution is a supervision construction procedure that generates explicit support examples together with semantically controlled non-support examples, including counterfactual wrong-state and topic-related negatives, without manual evidence annotation. We instantiate the framework in radiology and train a standard verifier on the resulting support task. The learned verifier substantially outperforms both case-only and evidence-only baselines, remains strong under correct evidence, and collapses when evidence is removed or swapped, indicating genuine evidence dependence. This behavior transfers across unseen evidence articles and an external case distribution, though performance degrades under evidence-source shift and remains sensitive to backbone choice. Overall, the results suggest that a major bottleneck in evidence grounding is not only model capacity, but the lack of supervision that encodes the causal role of evidence.

Clinical LLMs are often scaled by increasing model size, context length, retrieval complexity, or inference-time compute, with the implicit expectation that higher accuracy implies safer behavior. This assumption is incomplete in medicine, where a few confident, high-risk, or evidence-contradicting errors can matter more than average benchmark performance. We introduce SaFE-Scale, a framework for measuring how clinical LLM safety changes across model scale, evidence quality, retrieval strategy, context exposure, and inference-time compute. To instantiate this framework, we introduce RadSaFE-200, a Radiology Safety-Focused Evaluation benchmark of 200 multiple-choice questions with clinician-defined clean evidence, conflict evidence, and option-level labels for high-risk error, unsafe answer, and evidence contradiction. We evaluated 34 locally deployed LLMs across six deployment conditions: closed-book prompting (zero-shot), clean evidence, conflict evidence, standard RAG, agentic RAG, and max-context prompting. Clean evidence produced the strongest improvement, increasing mean accuracy from 73.5% to 94.1%, while reducing high-risk error from 12.0% to 2.6%, contradiction from 12.7% to 2.3%, and dangerous overconfidence from 8.0% to 1.6%. Standard RAG and agentic RAG did not reproduce this safety profile: agentic RAG improved accuracy over standard RAG and reduced contradiction, but high-risk error and dangerous overconfidence remained elevated. Max-context prompting increased latency without closing the safety gap, and additional inference-time compute produced only limited gains. Worst-case analysis showed that clinically consequential errors concentrated in a small subset of questions. Clinical LLM safety is therefore not a passive consequence of scaling, but a deployment property shaped by evidence quality, retrieval design, context construction, and collective failure behavior.

Retrieval-enhanced methods have become a primary approach in fact verification (FV); it requires reasoning over multiple retrieved pieces of evidence to verify the integrity of a claim. To retrieve evidence, existing work often employs off-the-shelf retrieval models whose design is based on the probability ranking principle. We argue that, rather than relevance, for FV we need to focus on the utility that a claim verifier derives from the retrieved evidence. We introduce the feedback-based evidence retriever(FER) that optimizes the evidence retrieval process by incorporating feedback from the claim verifier. As a feedback signal we use the divergence in utility between how effectively the verifier utilizes the retrieved evidence and the ground-truth evidence to produce the final claim label. Empirical studies demonstrate the superiority of FER over prevailing baselines.

Large language models (LLMs) are transforming the landscape of medicine, yet two fundamental challenges persist: keeping up with rapidly evolving medical knowledge and providing verifiable, evidence-grounded reasoning. Retrieval-augmented generation (RAG) has been widely adopted to address these limitations by supplementing model outputs with retrieved evidence. However, whether RAG reliably achieves these goals remains unclear. Here, we present the most comprehensive expert evaluation of RAG in medicine to date. Eighteen medical experts contributed a total of 80,502 annotations, assessing 800 model outputs generated by GPT-4o and Llama-3.1-8B across 200 real-world patient and USMLE-style queries. We systematically decomposed the RAG pipeline into three components: (i) evidence retrieval (relevance of retrieved passages), (ii) evidence selection (accuracy of evidence usage), and (iii) response generation (factuality and completeness of outputs). Contrary to expectation, standard RAG often degraded performance: only 22% of top-16 passages were relevant, evidence selection remained weak (precision 41-43%, recall 27-49%), and factuality and completeness dropped by up to 6% and 5%, respectively, compared with non-RAG variants. Retrieval and evidence selection remain key failure points for the model, contributing to the overall performance drop. We further show that simple yet effective strategies, including evidence filtering and query reformulation, substantially mitigate these issues, improving performance on MedMCQA and MedXpertQA by up to 12% and 8.2%, respectively. These findings call for re-examining RAG's role in medicine and highlight the importance of stage-aware evaluation and deliberate system design for reliable medical LLM applications.

How do we most effectively treat a disease or condition? Ideally, we could consult a database of evidence gleaned from clinical trials to answer such questions. Unfortunately, no such database exists; clinical trial results are instead disseminated primarily via lengthy natural language articles. Perusing all such articles would be prohibitively time-consuming for healthcare practitioners; they instead tend to depend on manually compiled systematic reviews of medical literature to inform care. NLP may speed this process up, and eventually facilitate immediate consult of published evidence. The Evidence Inference dataset was recently released to facilitate research toward this end. This task entails inferring the comparative performance of two treatments, with respect to a given outcome, from a particular article (describing a clinical trial) and identifying supporting evidence. For instance: Does this article report that chemotherapy performed better than surgery for five-year survival rates of operable cancers? In this paper, we collect additional annotations to expand the Evidence Inference dataset by 25\%, provide stronger baseline models, systematically inspect the errors that these make, and probe dataset quality. We also release an abstract only (as opposed to full-texts) version of the task for rapid model prototyping. The updated corpus, documentation, and code for new baselines and evaluations are available at http://evidence-inference.ebm-nlp.com/.

Recent large language models often answer factual questions correctly. But users can't trust any given claim a model makes without fact-checking, because language models can hallucinate convincing nonsense. In this work we use reinforcement learning from human preferences (RLHP) to train "open-book" QA models that generate answers whilst also citing specific evidence for their claims, which aids in the appraisal of correctness. Supporting evidence is drawn from multiple documents found via a search engine, or from a single user-provided document. Our 280 billion parameter model, GopherCite, is able to produce answers with high quality supporting evidence and abstain from answering when unsure. We measure the performance of GopherCite by conducting human evaluation of answers to questions in a subset of the NaturalQuestions and ELI5 datasets. The model's response is found to be high-quality 80\% of the time on this Natural Questions subset, and 67\% of the time on the ELI5 subset. Abstaining from the third of questions for which it is most unsure improves performance to 90\% and 80\% respectively, approaching human baselines. However, analysis on the adversarial TruthfulQA dataset shows why citation is only one part of an overall strategy for safety and trustworthiness: not all claims supported by evidence are true.

Large language models (LLMs) increasingly summarize clinical evidence, where a claim's weight depends on how strongly it is supported. Yet these models convey confidence poorly, and properties they never state, such as truth, are often readable from their activations. Whether a clinical model registers evidence strength, distinct from truth, and states it when asked is untested, and any such signal could be lexical. We compiled 45,134 clinical claims from six public sources, harmonized 20,611 into a four-level evidence grade under three independent frameworks, and tested 22 local, open-weight LLMs from several developers (0.6-70 billion parameters; general, medical, and reasoning), with lexical, truth, and cross-framework controls. A linear estimator recovered the grade in every model (median AUROC 71.8), yet decodability did not rise with scale and was weakest in reasoning models. The grade the models stated fell to chance, 25-27 percentage points below the estimator. The recoverable signal was largely lexical and did not transfer across topics or frameworks, yet it was distinct from factual truth and still flagged weakly supported claims (AUROC 69.2). Clinical LLMs thus carry an ordered evidence-strength signal they do not express, so their stated grades fail to convey a claim's support even when it is recoverable from their representations and text.

Deep research requires models to retrieve, connect, and synthesize evidence from large-scale heterogeneous sources to answer complex queries and produce analytical reports. Existing benchmarks mainly evaluate final outcomes, such as answer correctness, report quality, or citation alignment, while providing limited visibility into whether evidence is correctly selected, linked, and aggregated into supported claims and conclusions. To address this gap, we introduce HiEviDR-Bench, a benchmark for evaluating Hierarchical Evidence Aggregation in Deep Research. HiEviDR-Bench covers open-domain and academic-domain settings under both text-only and multimodal conditions, and represents each instance with an explicit evidence graph that captures evidence selection, cross-source linking, and aggregation from evidence to intermediate claims and final conclusions. Based on this formulation, we develop a traceability-oriented evaluation framework with five dimensions: report quality, evidence traceability, citation accuracy, claim verification, and answer correctness, together with a progressive gating mechanism for fine-grained error localization. HiEviDR-Bench contains 2,000 human-validated questions with evidence graphs across multiple difficulty levels. Experiments on 16 representative multimodal large language models show that, although many systems achieve strong report quality, their performance drops markedly on citation accuracy, claim construction, and answer correctness. Further analysis shows that the main bottlenecks lie in evidence identification and intermediate claim construction, revealing that strong surface-level report quality does not necessarily imply grounded multi-stage reasoning on our benchmark.

This paper describes the results of SemEval 2023 task 7 -- Multi-Evidence Natural Language Inference for Clinical Trial Data (NLI4CT) -- consisting of 2 tasks, a Natural Language Inference (NLI) task, and an evidence selection task on clinical trial data. The proposed challenges require multi-hop biomedical and numerical reasoning, which are of significant importance to the development of systems capable of large-scale interpretation and retrieval of medical evidence, to provide personalized evidence-based care. Task 1, the entailment task, received 643 submissions from 40 participants, and Task 2, the evidence selection task, received 364 submissions from 23 participants. The tasks are challenging, with the majority of submitted systems failing to significantly outperform the majority class baseline on the entailment task, and we observe significantly better performance on the evidence selection task than on the entailment task. Increasing the number of model parameters leads to a direct increase in performance, far more significant than the effect of biomedical pre-training. Future works could explore the limitations of large models for generalization and numerical inference, and investigate methods to augment clinical datasets to allow for more rigorous testing and to facilitate fine-tuning. We envisage that the dataset, models, and results of this task will be useful to the biomedical NLI and evidence retrieval communities. The dataset, competition leaderboard, and website are publicly available.

Although much research has focused on AI explanations to support decisions in complex information-seeking tasks such as fact-checking, the role of evidence is surprisingly under-researched. In our study, we systematically varied explanation type, AI prediction certainty, and correctness of AI system advice for non-expert participants, who evaluated the veracity of claims and AI system predictions. Participants were provided the option of easily inspecting the underlying evidence. We found that participants consistently relied on evidence to validate AI claims across all experimental conditions. When participants were presented with natural language explanations, evidence was used less frequently although they relied on it when these explanations seemed insufficient or flawed. Qualitative data suggests that participants attempted to infer evidence source reliability, despite source identities being deliberately omitted. Our results demonstrate that evidence is a key ingredient in how people evaluate the reliability of information presented by an AI system and, in combination with natural language explanations, offers valuable support for decision-making. Further research is urgently needed to understand how evidence ought to be presented and how people engage with it in practice.

We contribute the largest publicly available dataset of naturally occurring factual claims for the purpose of automatic claim verification. It is collected from 26 fact checking websites in English, paired with textual sources and rich metadata, and labelled for veracity by human expert journalists. We present an in-depth analysis of the dataset, highlighting characteristics and challenges. Further, we present results for automatic veracity prediction, both with established baselines and with a novel method for joint ranking of evidence pages and predicting veracity that outperforms all baselines. Significant performance increases are achieved by encoding evidence, and by modelling metadata. Our best-performing model achieves a Macro F1 of 49.2%, showing that this is a challenging testbed for claim veracity prediction.

Access to the right evidence does not guarantee that large language models (LLMs) will reason with it correctly. This gap between retrieval and reasoning is especially concerning in clinical settings, where outputs must align with structured protocols. We study this gap using Written Exposure Therapy (WET) guidelines as a testbed. In evaluating model responses to curated clinician-vetted questions, we find that errors persist even when authoritative passages are provided. To address this, we propose an evaluation framework that measures accuracy, consistency, and fidelity of reasoning. Our results highlight both the potential and the risks: retrieval-augmented generation (RAG) can constrain outputs, but safe deployment requires assessing reasoning as rigorously as retrieval.

Retrieval-augmented generation (RAG) improves large language models (LMs) by incorporating non-parametric knowledge through evidence retrieved from external sources. However, it often struggles to cope with inconsistent and irrelevant information that can distract the LM from its tasks, especially when multiple evidence pieces are required. While compressing the retrieved evidence with a compression model aims to address this issue, the compressed evidence may still be unfamiliar to the target model used for downstream tasks, potentially failing to utilize the evidence effectively. We propose FaviComp (Familarity-Aware Evidence Compression), a novel training-free evidence compression technique that makes retrieved evidence more familiar to the target model, while seamlessly integrating parametric knowledge from the model. Experimental results show that FaviComp consistently outperforms most recent evidence compression baselines across multiple open-domain QA datasets, improving accuracy by up to 28.1% while achieving high compression rates. Additionally, we demonstrate the effective integration of both parametric and non-parametric knowledge during evidence compression.

Large Reasoning Models (LRMs) have achieved remarkable success, yet they often suffer from producing unnecessary and verbose reasoning chains. We identify a core aspect of this issue as "invalid thinking" -- models tend to repeatedly double-check their work after having derived the correct answer. To address this specific inefficiency, we move beyond the general principles of Efficacy and Efficiency to propose two new, fine-grained principles: Brevity, which advocates for eliminating redundancy, and Sufficiency, which ensures critical reasoning steps are preserved. Guided by these principles, we introduce LC-R1, a post-training method based on Group Relative Policy Optimization (GRPO). LC-R1 employs a novel combination of a Length Reward for overall conciseness and a Compress Reward that is specifically designed to remove the invalid portion of the thinking process. Extensive experiments on multiple reasoning benchmarks demonstrate that LC-R1 achieves a significant reduction in sequence length (~50%) with only a marginal (~2%) drop in accuracy, achieving a favorable trade-off point on the Pareto frontier that prioritizes high compression. Our analysis further validates the robustness of LC-R1 and provides valuable insights for developing more powerful yet computationally efficient LRMs. Our code is released at https://github.com/zxiangx/LC-R1.

Multimodal large language models (MLLMs) have advanced clinical tasks for common conditions, but their performance on rare diseases remains largely untested. In rare-disease scenarios, clinicians often lack prior clinical knowledge, forcing them to rely strictly on case-level evidence for clinical judgments. Existing benchmarks predominantly evaluate common-condition, single-image settings, leaving multimodal and multi-image evidence integration under rare-disease data scarcity systematically unevaluated. We introduce MMRareBench, to our knowledge the first rare-disease benchmark jointly evaluating multimodal and multi-image clinical capability across four workflow-aligned tracks: diagnosis, treatment planning, cross-image evidence alignment, and examination suggestion. The benchmark comprises 1,756 question-answer pairs with 7,958 associated medical images curated from PMC case reports, with Orphanet-anchored ontology alignment, track-specific leakage control, evidence-grounded annotations, and a two-level evaluation protocol. A systematic evaluation of 23 MLLMs reveals fragmented capability profiles and universally low treatment-planning performance, with medical-domain models trailing general-purpose MLLMs substantially on multi-image tracks despite competitive diagnostic scores. These patterns are consistent with a capacity dilution effect: medical fine-tuning can narrow the diagnostic gap but may erode the compositional multi-image capability that rare-disease evidence integration demands.

Large Language Models (LLMs) are fluent but prone to hallucinations, producing answers that appear plausible yet are unsupported by available evidence. This failure is especially problematic in high-stakes domains where decisions must be justified by verifiable information. We introduce EvidenceRL, a reinforcement learning framework that enforces evidence adherence during training. EvidenceRL scores candidate responses for grounding (entailment with retrieved evidence and context) and correctness (agreement with reference answers) and optimizes the generator using Group Relative Policy Optimization (GRPO). We evaluate across two high-stakes domains, cardiac diagnosis and legal reasoning, where EvidenceRL consistently improves evidence grounding and faithfulness without sacrificing task accuracy. On cardiac diagnosis, F1@3 increases from 37.0 to 54.5 on Llama-3.2-3B while grounding (G_{max}@3) rises from 47.6 to 78.2; hallucinations drop nearly 5times and evidence-supported diagnoses increase from 31.8\% to 61.6\%. On legal reasoning, EvidenceRL raises Faithfulness from 32.8\% to 67.6\% on Llama-3.1-8B, demonstrating consistent behavioral change across domains. Our code is open-sourced at https://github.com/Wizaaard/EvidenceRL.git.

Current medical retrieval benchmarks primarily emphasize lexical or shallow semantic similarity, overlooking the reasoning-intensive demands that are central to clinical decision-making. In practice, physicians often retrieve authoritative medical evidence to support diagnostic hypotheses. Such evidence typically aligns with an inferred diagnosis rather than the surface form of a patient's symptoms, leading to low lexical or semantic overlap between queries and relevant documents. To address this gap, we introduce R2MED, the first benchmark explicitly designed for reasoning-driven medical retrieval. It comprises 876 queries spanning three tasks: Q&A reference retrieval, clinical evidence retrieval, and clinical case retrieval. These tasks are drawn from five representative medical scenarios and twelve body systems, capturing the complexity and diversity of real-world medical information needs. We evaluate 15 widely-used retrieval systems on R2MED and find that even the best model achieves only 31.4 nDCG@10, demonstrating the benchmark's difficulty. Classical re-ranking and generation-augmented retrieval methods offer only modest improvements. Although large reasoning models improve performance via intermediate inference generation, the best results still peak at 41.4 nDCG@10. These findings underscore a substantial gap between current retrieval techniques and the reasoning demands of real clinical tasks. We release R2MED as a challenging benchmark to foster the development of next-generation medical retrieval systems with enhanced reasoning capabilities. Data and code are available at https://github.com/R2MED/R2MED

Professional-document review is a constraint-checking problem in which decisions depend on relations among text, geometry, pages, and document revisions. We present an evidence-grounded pipeline that normalizes extracted facts, executes four-state rules deterministically, retains source spans, and escalates unresolved cases. We evaluate its PDF evidence allocator on 160 reference-based tasks from 29 construction projects using a repeated four-system test and a disjoint two-system breadth extension. In the repeated test, reallocating a four-image budget from retrieved page overviews to one overview and three overlapping tiles improves project-family standardized decision accuracy by 10.6 percentage points (95% project-cluster bootstrap CI: 4.3 to 18.0; exact p = 0.031). This effect does not persist in the broader block: Region-RAG changes accuracy by -4.1 points (95% CI: -10.2 to 1.9; exact p = 0.209), while an equal-image sensitivity favors page breadth. Exact finding-set recovery remains low, false passes remain common, and repeated-run agreement is poorly calibrated. The results identify a resolution-breadth trade-off rather than a universal advantage for region-focused evidence, motivating rule-aware evidence routing and expert review.

We present a complete theoretical characterization of Latent Posterior Factors (LPF), a principled framework for aggregating multiple heterogeneous evidence items in probabilistic prediction tasks. Multi-evidence reasoning arises pervasively in high-stakes domains including healthcare diagnosis, financial risk assessment, legal case analysis, and regulatory compliance, yet existing approaches either lack formal guarantees or fail to handle multi-evidence scenarios architecturally. LPF encodes each evidence item into a Gaussian latent posterior via a variational autoencoder, converting posteriors to soft factors through Monte Carlo marginalization, and aggregating factors via exact Sum-Product Network inference (LPF-SPN) or a learned neural aggregator (LPF-Learned). We prove seven formal guarantees spanning the key desiderata for trustworthy AI: Calibration Preservation (ECE <= epsilon + C/sqrt(K_eff)); Monte Carlo Error decaying as O(1/sqrt(M)); a non-vacuous PAC-Bayes bound with train-test gap of 0.0085 at N=4200; operation within 1.12x of the information-theoretic lower bound; graceful degradation as O(epsilon*delta*sqrt(K)) under corruption, maintaining 88% performance with half of evidence adversarially replaced; O(1/sqrt(K)) calibration decay with R^2=0.849; and exact epistemic-aleatoric uncertainty decomposition with error below 0.002%. All theorems are empirically validated on controlled datasets spanning up to 4,200 training examples. Our theoretical framework establishes LPF as a foundation for trustworthy multi-evidence AI in safety-critical applications.

Chain-of-Thought (CoT) prompting helps Large Language Models (LLMs) tackle complex reasoning by eliciting explicit step-by-step rationales. However, CoT's verbosity increases latency and memory usage and may propagate early errors across long chains. We propose the Reasoning Capsule (R-Capsule), a framework that aims to combine the efficiency of latent reasoning with the transparency of explicit CoT. The core idea is to compress the high-level plan into a small set of learned latent tokens (a Reasoning Capsule) while keeping execution steps lightweight or explicit. This hybrid approach is inspired by the Information Bottleneck (IB) principle, where we encourage the capsule to be approximately minimal yet sufficient for the task. Minimality is encouraged via a low-capacity bottleneck, which helps improve efficiency. Sufficiency is encouraged via a dual objective: a primary task loss for answer accuracy and an auxiliary plan-reconstruction loss that encourages the capsule to faithfully represent the original textual plan. The reconstruction objective helps ground the latent space, thereby improving interpretability and reducing the use of uninformative shortcuts. Our framework strikes a balance between efficiency, accuracy, and interpretability, thereby reducing the visible token footprint of reasoning while maintaining or improving accuracy on complex benchmarks. Our codes are available at: https://anonymous.4open.science/r/Reasoning-Capsule-7BE0

Equipping agents with the capacity to justify made decisions using supporting evidence represents a cornerstone of accountable decision-making. Furthermore, ensuring that justifications are in line with human expectations and societal norms is vital, especially in high-stakes situations such as healthcare. In this work, we propose the use of a debate-based reward model for reinforcement learning agents, where the outcome of a zero-sum debate game quantifies the justifiability of a decision in a particular state. This reward model is then used to train a justifiable policy, whose decisions can be more easily corroborated with supporting evidence. In the debate game, two argumentative agents take turns providing supporting evidence for two competing decisions. Given the proposed evidence, a proxy of a human judge evaluates which decision is better justified. We demonstrate the potential of our approach in learning policies for prescribing and justifying treatment decisions of septic patients. We show that augmenting the reward with the feedback signal generated by the debate-based reward model yields policies highly favored by the judge when compared to the policy obtained solely from the environment rewards, while hardly sacrificing any performance. Moreover, in terms of the overall performance and justifiability of trained policies, the debate-based feedback is comparable to the feedback obtained from an ideal judge proxy that evaluates decisions using the full information encoded in the state. This suggests that the debate game outputs key information contained in states that is most relevant for evaluating decisions, which in turn substantiates the practicality of combining our approach with human-in-the-loop evaluations. Lastly, we showcase that agents trained via multi-agent debate learn to propose evidence that is resilient to refutations and closely aligns with human preferences.

Retrieval-augmented generation (RAG) is typically optimized for topical relevance, yet its success ultimately depends on whether retrieved passages are useful for a large language model (LLM) to generate correct and complete answers. We argue that such utility is often LLM-specific rather than universal, due to differences in models' knowledge, reasoning, and ability to leverage evidence. We formalize LLM-specific utility as the performance improvement of a target LLM when a passage is provided, compared to answering without evidence. To systematically study LLM-specific utility, we construct a benchmark of LLM-specific gold utilitarian passages for four LLMs (Qwen3-8B/14B/32B and Llama3.1-8B) on three QA datasets (Natural Questions, TriviaQA, and MS MARCO-FQA). Our analysis shows that utilitarian passages are model-dependent and non-transferable: each LLM performs best with its own utilitarian evidence, while evidence optimized for other LLMs is consistently suboptimal. Human-annotated evidence remains a strong general baseline but does not fully match individual LLM utility needs. We further introduce the LLM-specific utility judgment task and find that existing utility-aware selection and scoring methods largely capture model-agnostic usefulness and struggle to reliably estimate LLM-specific utility. Overall, our findings highlight the limitations of current utility-aware retrieval and motivate generator-tailored evidence selection for improving RAG.

Medical Vision-Language Models (Med-VLMs) require reliable reasoning from fine-grained visual evidence, yet existing models can produce plausible clinical answers by relying on language priors or medical templates rather than truly attending to diagnosis-critical regions. On-Policy Distillation (OPD) offers dense token-level supervision on student-generated trajectories and provides a privacy-compatible means of capability transfer without requiring the redistribution of raw patient data. However, standard OPD uniformly distills all tokens, causing sparse evidence-dependent tokens to be diluted by abundant clinical narrative tokens. Inspired by the success of OPD in the large language model community, we propose Med-OPD, to our knowledge the first unified post-training framework that integrates on-policy distillation with medical evidence-aware supervision for Med-VLMs. We introduce Medical Evidence Advantage (MEA), a teacher-grounded counterfactual signal that uses an answer-aware hint to focus teacher scoring on evidence supporting the target diagnosis, and measures each token's dependence on medical visual evidence by comparing teacher likelihoods under the original and evidence-degraded imaging modalities. Based on MEA, Med-OPD redistributes the distillation signal at both the token and trajectory levels, emphasizing diagnosis-critical tokens and evidence-reliant rollouts. Experiments on OmniMedVQA subsets show that Med-OPD consistently outperforms SFT and standard OPD across CT, MRI, Disease Diagnosis, and Lesion Grading. These results demonstrate that evidence-aware distillation can better strengthen medical VLMs' reliance on key visual evidence and improve reliable multimodal medical reasoning. The source code and data is publicly available at: https://github.com/yunhang8658/MedOPD.git

Many modern AI question-answering systems convert text into vectors and retrieve the closest matches to a user question. While effective for topical similarity, similarity scores alone do not explain why some retrieved text can serve as evidence while other equally similar text cannot. When many candidates receive similar scores, systems may select sentences that are redundant, incomplete, or address different conditions than the question requires. This paper presents a deterministic evidence selection framework for retrieval-augmented question answering. The approach introduces Meaning-Utility Estimation (MUE) and Diversity-Utility Estimation (DUE), fixed scoring and redundancy-control procedures that determine evidence admissibility prior to answer generation. Each sentence or record is evaluated independently using explicit signals for semantic relatedness, term coverage, conceptual distinctiveness, and redundancy. No training or fine-tuning is required. In the prototype, a unit is accepted only if it explicitly states the fact, rule, or condition required by the task. Units are not merged or expanded. If no unit independently satisfies the requirement, the system returns no answer. This deterministic gating produces compact, auditable evidence sets and establishes a clear boundary between relevant text and usable evidence.

LLM agents choose tools and arguments from context that mixes user requests, tool outputs, retrieved records, memory, and untrusted text. Evidence can be relevant without being authorized to determine a decision, so a correct action need not be grounded only in permitted evidence. We introduce a target-specific authorization audit that labels context factors separately for each tool and argument target. Its primary test holds the task, proposition, position, and policy fixed while changing only the proposition's source authority. We then test behavior when valid evidence is weakened and use context-subset interactions as a secondary localization diagnostic. Across 450 controlled next-action tasks and multiple open-weight LLM families, trusted and untrusted variants produce different actions in 5.4 percent of competing cases versus 1.7 percent of supporting cases. Under controlled degradation, unauthorized competition is retained in a full-correct, mixed-error, clean-correct pattern in 2.4 percent of comparisons, with a 95 percent confidence interval from 2.1 to 3.0 percent. These are controlled stress-set rates, not deployment prevalence. The models respond to textual source-authority cues, but this does not prevent untrusted evidence from influencing their actions.

Scientific research based on multimodal clinical data (including medical imaging) requires coordinating clinical, radiological, programming, and biostatistical expertise, a fragmented process that bottlenecks discovery. We present VERITAS (Verifiable Epistemic Reasoning for Image-Derived Hypothesis Testing via Agentic Systems), a clinical co-scientist: a multi-agent system that autonomously tests natural-language hypotheses and produces a fully auditable evidence trail, tracing every conclusion through executable outputs from analysis plan to segmentation masks to statistical code to final verdict. Unlike prior AI-scientist systems, which mainly operate on tabular or text data, VERITAS grounds autonomous discovery directly in medical images. It decomposes the workflow into four phases handled by role-specialized agents, and introduces an epistemic evidence label framework that mechanically classifies outcomes as Supported, Refuted, Underpowered, or Invalid by jointly evaluating significance, effect direction, and study power. This distinction is critical in medical imaging, where non-significant results often reflect insufficient sample size rather than absent effects. We construct a tiered benchmark of 64 hypotheses spanning six complexity levels across cardiac and brain glioma MRI datasets. VERITAS reaches 81.4% verdict accuracy with frontier models and 71.2% with locally-hosted open-weight models (8-30B), outperforming all single-model baselines in both classes. It also produces the highest rate of independently verifiable statistical outputs (86.6%), so even its failures remain diagnosable through artifact inspection. Structured multi-agent decomposition thus substitutes for model scale while preserving the verifiability that scientific discovery demands. We release code, hypothesis bank, and evaluation pipeline at https://github.com/LucZot/veritas.

Benchmarks increasingly guide deployment, procurement and scientific screening, yet a score supports only the response it records, not necessarily the deployment action. We introduce deployment-complete benchmarking, which tests whether benchmark evidence determines a deployment action. A benchmark is complete for a claim exactly when the action is constant on each evidence fiber; mixed fibers expose missing deployment information, and completion curves quantify the evidence required to resolve ambiguity. In controlled response spaces, benchmark-channel conformal coverage of 94.98% transferred poorly to an unmeasured deployment channel (10.07%), whereas response-rank intervals achieved 94.91% coverage; even zero benchmark error certified only 45.4% of candidates at the largest residual size. Public audits revealed incompleteness, including 97.9% mixed Tox21 fibers and zero median certifiable fraction in main Matbench and JARVIS audits. In held-out replays, certify-then-acquire reduced false decisions from 1.19% to 0.027% in Tox21 and from 20.3% to 0.128% in JARVIS, while changing model choice and identifying deployment-relevant probes. Deployment-ready benchmarks should report evidence, supported actions, ambiguity and completion cost rather than scores alone.

Across medical specialties, clinical practice is anchored in evidence-based guidelines that codify best studied diagnostic and treatment pathways. These pathways routinely fall short for the long tail of real-world care not covered by guidelines. Most medical large language models (LLMs), however, are trained to encode common, guideline-focused medical knowledge in their parameters. Current evaluations test models primarily on recalling and reasoning with this memorized content, often in multiple-choice settings. Given the fundamental importance of evidence-based reasoning in medicine, it is neither feasible nor reliable to depend on memorization in practice. To address this gap, we introduce OGCaReBench, a free-form retrieval-focused benchmark aimed at evaluating LLMs at answering clinical questions that require going beyond typical guidelines. Extracted from published medical case reports and validated by medical experts, OGCaReBench contains long-form clinical questions requiring free-text answers, providing a systematic framework for assessing open-ended medical reasoning in rare, case-based scenarios. Our experiments reveal that even the best-performing baseline (GPT-5.2) correctly answers only 56% of our benchmark with specialized models only reaching 42%. Augmenting models with retrieved medical articles improves this performance to up to 82% (using GPT-5.2) highlighting the importance of evidence-grounding for real-world medical reasoning tasks. This work thus establishes a foundation for benchmarking and advancing both general-purpose and medical LLMs to produce reliable answers in challenging clinical contexts.

Existing methods for multimodal sentiment analysis (MSA) under missing modalities usually follow a repair-first paradigm. We revisit this assumption and ask: should every missing modality be repaired? A per-sample oracle analysis shows the answer is not always: full-modality input is optimal for only a small fraction of samples, and every modality subset is preferred by some samples. These results suggest that adding or repairing modalities may not always improve prediction, and that the utility of each modality is sample-dependent. Building on this finding, we propose Sufficiency-Informed Evidential ValvE (SIEVE) that turns ``whether to repair'' into an explicit, learnable decision at the sample level. SIEVE compares a direct prediction branch with a repair branch, derives an empirical sufficiency signal from their per-sample loss gap, and routes each input through an evidential gate that jointly models sufficiency and its epistemic uncertainty. SIEVE is repair-agnostic: it operates as a plug-and-play decision on top of any explicit or implicit repair module, without modifying its internal design. Experiments on CMU-MOSI and IEMOCAP show that SIEVE consistently improves representative repair backbones across evaluated missing rates, and approaches the per-sample dual-branch achievable optimum.

Clinical evidence, derived from rigorous research and data analysis, provides healthcare professionals with reliable scientific foundations for informed decision-making. Integrating clinical evidence into real-time practice is challenging due to the enormous workload, complex professional processes, and time constraints. This highlights the need for tools that automate evidence synthesis to support more efficient and accurate decision making in clinical settings. This study introduces Quicker, an evidence-based clinical decision support system powered by large language models (LLMs), designed to automate evidence synthesis and generate clinical recommendations modeled after standard clinical guideline development processes. Quicker implements a fully automated chain that covers all phases, from questions to clinical recommendations, and further enables customized decision-making through integrated tools and interactive user interfaces. To evaluate Quicker's capabilities, we developed the Q2CRBench-3 benchmark dataset, based on clinical guideline development records for three different diseases. Experimental results highlighted Quicker's strong performance, with fine-grained question decomposition tailored to user preferences, retrieval sensitivities comparable to human experts, and literature screening performance approaching comprehensive inclusion of relevant studies. In addition, Quicker-assisted evidence assessment effectively supported human reviewers, while Quicker's recommendations were more comprehensive and logically coherent than those of clinicians. In system-level testing, collaboration between a single reviewer and Quicker reduced the time required for recommendation development to 20-40 minutes. In general, our findings affirm the potential of Quicker to help physicians make quicker and more reliable evidence-based clinical decisions.

AI research often requires decisions before future evidence exists: which bottleneck to attack, which direction to pursue, or where a project should be positioned. We introduce ForeSci, a temporally controlled benchmark for evaluating whether LLM agents can make such forward-looking research judgements from historical evidence. ForeSci contains 500 tasks across four fast-moving AI domains and four decision families. Each task is paired with a cutoff-aligned offline knowledge base; post-cutoff papers are hidden during generation and used only for validation. To avoid random future-event prediction, tasks are derived from pre-cutoff taxonomy branches and evidence signals, and answer-generation backbones are selected to precede the task cutoffs. We evaluate native LLMs, Hybrid RAG, and three research-agent adaptations across four backbones. Results show that explicit evidence organization improves traceability and factual support, but gains depend strongly on the decision family. Diagnostics reveal a recurring evidence-decision decoupling: agents may cite relevant evidence while forecasting the wrong research object. ForeSci turns forward-looking AI research judgement into a controlled benchmark for evaluating research agents as decision-making systems.

Large-taxonomy retrieval often assumes that the input already expresses the target concept. In many settings, however, the input is indirect evidence, such as a table cell whose meaning depends on its row, column, datatype, and context. We call this mismatch the retrieval readiness gap. Our analysis shows that the current index retrieves the target reliably when its semantics are explicit, while raw evidence often leaves it deep in the ranking. We propose Factorized Hypothesis Search (FHS), which maintains multiple partial interpretations over named semantic dimensions. These hypotheses support structured query rendering, multi-hypothesis retrieval, and dimension-level candidate verification. On both financial taxonomy tagging and CodiEsp clinical coding tasks, FHS achieves the best Recall@1, MRR, and final accuracy among the non-oracle methods. Replacing the factorized hypothesis path with a free-text ensemble causes the largest drop in head-ranking performance, while sequential refinement provides no additional gain over FHS's strong parallel first round.

Emerging personal AI agents are moving toward persistent, multi-source memory. This creates an evaluation problem: systems must decide how to use conflicting or incomplete evidence; they cannot just retrieve facts from one clean history. Existing benchmarks rarely show whether an error came from the evidence given to a method or from the method's conflict-resolution step. We study this as selective QA over conflicting multi-source personal memory: systems answer based on conflicting, sometimes incomplete sources, or abstain when evidence is insufficient. We develop a benchmark containing 18 question templates across 8 reasoning types, 480 personas, 4 random seeds, and 34,560 instances, with controlled source distortions and deterministic ground truth. We evaluate the performance of baselines without access to any source, access to a single source, structured fusion methods, and frontier LLMs. The best trained fusion resolver reaches 80.3% accuracy, while the strongest prompt-only LLM baseline reaches 70.0%. With abstention, the same resolver reaches 85.3% selective accuracy at 78.3% coverage and the best LLM reaches 71.0% selective accuracy at 95.4% coverage. Different models have different strengths across reasoning types. We release the data, code, cached model outputs, and data-generating process for reuse.

Despite the potential of Large Language Models (LLMs) in medicine, they may generate responses lacking supporting evidence or based on hallucinated evidence. While Retrieval Augment Generation (RAG) is popular to address this issue, few studies implemented and evaluated RAG in downstream domain-specific applications. We developed a RAG pipeline with 70,000 ophthalmology-specific documents that retrieve relevant documents to augment LLMs during inference time. In a case study on long-form consumer health questions, we systematically evaluated the responses including over 500 references of LLMs with and without RAG on 100 questions with 10 healthcare professionals. The evaluation focuses on factuality of evidence, selection and ranking of evidence, attribution of evidence, and answer accuracy and completeness. LLMs without RAG provided 252 references in total. Of which, 45.3% hallucinated, 34.1% consisted of minor errors, and 20.6% were correct. In contrast, LLMs with RAG significantly improved accuracy (54.5% being correct) and reduced error rates (18.8% with minor hallucinations and 26.7% with errors). 62.5% of the top 10 documents retrieved by RAG were selected as the top references in the LLM response, with an average ranking of 4.9. The use of RAG also improved evidence attribution (increasing from 1.85 to 2.49 on a 5-point scale, P<0.001), albeit with slight decreases in accuracy (from 3.52 to 3.23, P=0.03) and completeness (from 3.47 to 3.27, P=0.17). The results demonstrate that LLMs frequently exhibited hallucinated and erroneous evidence in the responses, raising concerns for downstream applications in the medical domain. RAG substantially reduced the proportion of such evidence but encountered challenges.

Observational studies can yield clinically actionable evidence at scale, but executing them on real-world databases is open-ended and requires coherent decisions across cohort construction, analysis, and reporting. Prior evaluations of LLM agents emphasize isolated steps or single answers, missing the integrity and internal structure of the resulting evidence bundle. To address this gap, we introduce RWE-bench, a benchmark grounded in MIMIC-IV and derived from peer-reviewed observational studies. Each task provides the corresponding study protocol as the reference standard, requiring agents to execute experiments in a real database and iteratively generate tree-structured evidence bundles. We evaluate six LLMs (three open-source, three closed-source) under three agent scaffolds using both question-level correctness and end-to-end task metrics. Across 162 tasks, task success is low: the best agent reaches 39.9%, and the best open-source model reaches 30.4%. Agent scaffolds also matter substantially, causing over 30% variation in performance metrics. Furthermore, we implement an automated cohort evaluation method to rapidly localize errors and identify agent failure modes. Overall, the results highlight persistent limitations in agents' ability to produce end-to-end evidence bundles, and efficient validation remains an important direction for future work. Code and data are available at https://github.com/somewordstoolate/RWE-bench.

Scientific research follows multi-turn, multi-step workflows that require proactively searching the literature, consulting figures and tables, and integrating evidence across papers to align experimental settings and support reproducible conclusions. This joint capability is not systematically assessed in existing benchmarks, which largely under-evaluate proactive search, multi-evidence integration and sustained evidence use over time. In this work, we introduce EpiBench, an episodic multi-turn multimodal benchmark that instantiates short research workflows. Given a research task, agents must navigate across papers over multiple turns, align evidence from figures and tables, and use the accumulated evidence in the memory to answer objective questions that require cross paper comparisons and multi-figure integration. EpiBench introduces a process-level evaluation framework for fine-grained testing and diagnosis of research agents. Our experiments show that even the leading model achieves an accuracy of only 29.23% on the hard split, indicating substantial room for improvement in multi-turn, multi-evidence research workflows, providing an evaluation platform for verifiable and reproducible research agents.

Autonomous research agents produce competitive solutions and professional-looking manuscripts, yet their outputs contain verifiability failures undetectable by surface-level evaluation: fabricated citations, unreproducible scores, and method descriptions that diverge from the implementation. We address this through three contributions. First, Chain-of-Evidence (CoE), a verifiability framework requiring every claim to be traceable to its evidence source. Second, ScientistOne, an end-to-end autonomous research system that maintains evidence chains by construction throughout literature review, solution discovery, and paper writing. Third, CoE Audit, a post-hoc audit whose four integrity checks -- score verification, specification violation, reference verification, and method-code alignment -- apply uniformly to all systems. Across 75 papers spanning five systems and five frontier research tasks, every baseline exhibits at least one systematic failure mode: hallucinated reference rates reach 21%, score verification passes in as few as 42% of papers, and method-code alignment ranges from 20% to 80%. ScientistOne achieves zero hallucinated references (0/337), perfect score verification (12/12), and the highest method-code alignment (14/15), while matching or exceeding human expert performance on all five tasks. ScientistOne further generalizes to six additional tasks spanning medical imaging, fine-grained recognition, 3D perception, and language modeling, achieving state-of-the-art on Parameter Golf and gold medals on MLE-Bench tasks where baselines fail entirely.

Providing high quality explanations for AI predictions based on machine learning is a challenging and complex task. To work well it requires, among other factors: selecting a proper level of generality/specificity of the explanation; considering assumptions about the familiarity of the explanation beneficiary with the AI task under consideration; referring to specific elements that have contributed to the decision; making use of additional knowledge (e.g. expert evidence) which might not be part of the prediction process; and providing evidence supporting negative hypothesis. Finally, the system needs to formulate the explanation in a clearly interpretable, and possibly convincing, way. Given these considerations, ANTIDOTE fosters an integrated vision of explainable AI, where low-level characteristics of the deep learning process are combined with higher level schemes proper of the human argumentation capacity. ANTIDOTE will exploit cross-disciplinary competences in deep learning and argumentation to support a broader and innovative view of explainable AI, where the need for high-quality explanations for clinical cases deliberation is critical. As a first result of the project, we publish the Antidote CasiMedicos dataset to facilitate research on explainable AI in general, and argumentation in the medical domain in particular.

BoN improves model outputs by sampling several candidates and selecting one with a proxy score, but it assumes that complete candidates can be evaluated reliably. Many vision-language tasks instead provide only partial verification: a finding, span, value, region, or relation may be checkable even when no dependable whole-response verifier exists. Moreover, the same claim may recur across candidates with opposing stances, allowing one observation to support part of the pool and contradict another. We introduce Best-of-Evidence (BoE), an inference-time selection framework that keeps the BoN candidate pool fixed, represents reusable claims with a signed candidate--factor graph, and allocates a limited budget to evidence actions that can change the final choice. BoE formalizes selection under partial verification and provides a practical score-based controller, with the zero-budget case recovering the underlying BoN decision. Theoretically, we show that residual evidence capacity limits any evidence-driven improvement and that shared factor queries can achieve an O(log K) versus Θ(K) query separation in a factor-code model. Common-ledger experiments on four medical VQA settings show that BoE can improve fixed-pool selection and rescue some BoN failures when evidence is reliable, contrastive, and decision-relevant, while also revealing the channel-quality and candidate-generation limits that prevent universal gains.

While Reinforcement Learning (RL) has advanced LLM reasoning, applying it to long-context scenarios is hindered by sparsity of outcome rewards. This limitation fails to penalize ungrounded "lucky guesses," leaving the critical process of needle-in-a-haystack evidence retrieval largely unsupervised. To address this, we propose EAPO (Evidence-Augmented Policy Optimization). We first establish the Evidence-Augmented Reasoning paradigm, validating via Tree-Structured Evidence Sampling that precise evidence extraction is the decisive bottleneck for long-context reasoning. Guided by this insight, EAPO introduces a specialized RL algorithm where a reward model computes a Group-Relative Evidence Reward, providing dense process supervision to explicitly improve evidence quality. To sustain accurate supervision throughout training, we further incorporate an Adaptive Reward-Policy Co-Evolution mechanism. This mechanism iteratively refines the reward model using outcome-consistent rollouts, sharpening its discriminative capability to ensure precise process guidance. Comprehensive evaluations across eight benchmarks demonstrate that EAPO significantly enhances long-context reasoning performance compared to SOTA baselines.

As language models shift from single-shot answer generation toward multi-step reasoning that retrieves and consumes evidence mid-inference, evaluating the role of individual retrieved items becomes more important. Existing RAG evaluation typically targets final-answer quality, citation faithfulness, or answer-level attribution, but none of these directly targets the intervention-based, per-evidence-item utility view we study here. We introduce CUE-R, a lightweight intervention-based framework for measuring per-evidence-item operational utility in single-shot RAG using shallow observable retrieval-use traces. CUE-R perturbs individual evidence items via REMOVE, REPLACE, and DUPLICATE operators, then measures changes along three utility axes (correctness, proxy-based grounding faithfulness, and confidence error) plus a trace-divergence signal. We also outline an operational evidence-role taxonomy for interpreting intervention outcomes. Experiments on HotpotQA and 2WikiMultihopQA with Qwen-3 8B and GPT-5.2 reveal a consistent pattern: REMOVE and REPLACE substantially harm correctness and grounding while producing large trace shifts, whereas DUPLICATE is often answer-redundant yet not fully behaviorally neutral. A zero-retrieval control confirms that these effects arise from degradation of meaningful retrieval. A two-support ablation further shows that multi-hop evidence items can interact non-additively: removing both supports harms performance far more than either single removal. Our results suggest that answer-only evaluation misses important evidence effects and that intervention-based utility analysis is a practical complement for RAG evaluation.

While Large Language Models (LLMs) have demonstrated proficiency in Deep Research or Wide Search, their capacity to solve highly complex questions-those requiring long-horizon planning, massive evidence gathering, and synthesis across heterogeneous sources-remains largely unexplored. We introduce Super Research, a task for complex autonomous research tasks that integrates (i) structured decomposition into a research plan, (ii) super wide retrieval for diverse perspectives, and (iii) super deep investigation to resolve uncertainties through iterative queries. To evaluate this capability, we curated a benchmark of 300 expert-written questions across diverse domains, each requiring up to 100+ retrieval steps and 1,000+ web pages to reconcile conflicting evidence. Super Research produces verifiable reports with fine-grained citations and intermediate artifacts (e.g., outlines and tables) to ensure traceable reasoning. Furthermore, we present a graph-anchored auditing protocol that evaluates Super Research along five dimensions: Coverage, Logical Consistency, Report Utility, Objectivity and Citation Health. While super-complex questions may be infrequent in standard applications, Super Research serves as a critical ceiling evaluation and stress test for LLM capabilities. A model's proficiency within Super Research acts as a powerful proxy for its general research competence; success here suggests the robustness necessary to navigate nearly any subordinate research task. Leaderboard is available at: https://cnsdqd-dyb.github.io/Super-Research-Benchmark/

While Retrieval-Augmented Generation (RAG) mitigates hallucination and knowledge staleness in Large Language Models (LLMs), existing frameworks often falter on complex, multi-hop queries that require synthesizing information from disparate sources. Current advanced RAG methods, employing iterative or adaptive strategies, lack a robust mechanism to systematically identify and fill evidence gaps, often propagating noise or failing to gather a comprehensive context. We introduce FAIR-RAG, a novel agentic framework that transforms the standard RAG pipeline into a dynamic, evidence-driven reasoning process. At its core is an Iterative Refinement Cycle governed by a module we term Structured Evidence Assessment (SEA). The SEA acts as an analytical gating mechanism: it deconstructs the initial query into a checklist of required findings and audits the aggregated evidence to identify confirmed facts and, critically, explicit informational gaps. These gaps provide a precise signal to an Adaptive Query Refinement agent, which generates new, targeted sub-queries to retrieve missing information. This cycle repeats until the evidence is verified as sufficient, ensuring a comprehensive context for a final, strictly faithful generation. We conducted experiments on challenging multi-hop QA benchmarks, including HotpotQA, 2WikiMultiHopQA, and MusiQue. In a unified experimental setup, FAIR-RAG significantly outperforms strong baselines. On HotpotQA, it achieves an F1-score of 0.453 -- an absolute improvement of 8.3 points over the strongest iterative baseline -- establishing a new state-of-the-art for this class of methods on these benchmarks. Our work demonstrates that a structured, evidence-driven refinement process with explicit gap analysis is crucial for unlocking reliable and accurate reasoning in advanced RAG systems for complex, knowledge-intensive tasks.

Recent advances in large language models have enabled deep research systems that generate expert-level reports through multi-step reasoning and evidence-based synthesis. However, evaluating such reports remains challenging: report quality is multifaceted, making it difficult to determine what to assess and by what criteria; LLM-based judges may miss errors that require domain expertise to identify; and because deep research relies on retrieved evidence, report-wide claim verification is also necessary. To address these issues, we propose DEER, a benchmark for evaluating expert-level deep research reports. DEER systematizes evaluation criteria with an expert-developed taxonomy (7 dimensions, 25 subdimensions) operationalized as 101 fine-grained rubric items. We also provide task-specific Expert Evaluation Guidance to support LLM-based judging. Alongside rubric-based assessment, we propose a claim verification architecture that verifies both cited and uncited claims and quantifies evidence quality. Experiments show that while current deep research systems can produce structurally plausible reports that cite external evidence, there is room for improvement in fulfilling expert-level user requests and achieving logical completeness. Beyond simple performance comparisons, DEER makes system strengths and limitations interpretable and provides diagnostic signals for improvement.

Retrieval-Augmented Generation (RAG) is the prevailing paradigm for grounding Large Language Models (LLMs), yet the mechanisms governing how models integrate groups of conflicting retrieved evidence remain opaque. Does an LLM answer a certain way because the evidence is factually strong, because of a prior belief, or merely because it is repeated frequently? To answer this, we introduce GroupQA, a curated dataset of 1,635 controversial questions paired with 15,058 diversely-sourced evidence documents, annotated for stance and qualitative strength. Through controlled experiments, we characterize group-level evidence aggregation dynamics: Paraphrasing an argument can be more persuasive than providing distinct independent support; Models favor evidence presented first rather than last, and Larger models are increasingly resistant to adapt to presented evidence. Additionally, we find that LLM explanations to group-based answers are unfaithful. Together, we show that LLMs behave consistently as vulnerable heuristic followers, with direct implications for improving RAG system design.

Large language models (LLMs) and agentic systems have shown promise for clinical decision support, but existing works largely assume that evidence has already been curated and handed to the model. Real-world clinical workflows instead require agents to actively seek, iteratively plan, and synthesize multimodal evidence from heterogeneous sources. In this paper, we introduce ClinSeekAgent, an automated agentic framework for dynamic multimodal evidence seeking that shifts the paradigm from passive evidence consumption to active evidence acquisition. Given only a clinical query and access to raw data sources, ClinSeekAgent gathers evidence by querying medical knowledge bases, navigating raw EHRs, and invoking medical imaging tools; refines its hypotheses as new information emerges; and integrates the collected evidence into grounded clinical decisions. ClinSeekAgent serves both as an inference-time agent for frontier LLMs and as a training-time pipeline for distilling high-quality agent trajectories into compact open-source models. To validate its inference-time effectiveness, we construct ClinSeek-Bench, which pairs Curated Input reasoning from fixed pre-selected evidence with Automated Evidence-Seeking over raw clinical data. On text-only EHR tasks, ClinSeekAgent improves Claude Opus 4.6 from 60.0 to 63.2 overall F1 and MiniMax M2.5 from 43.1 to 47.3, with positive risk-prediction gains in 7 out of 9 evaluated host models. On multimodal tasks, ClinSeekAgent improves Claude Opus 4.6 from 47.5 to 62.6 (+15.1); all evaluated models improve across the three CXR-related task groups. We further validate ClinSeekAgent as a training pipeline by distilling agentic evidence-seeking trajectories into ClinSeek-35B-A3B, which achieves 34.0 average F1 on existing AgentEHR-Bench, improving over its Qwen3.5-35B-A3B baseline by +11.9 points and approaching Claude Opus 4.6.

Radiology report evaluation is essential for advancing automated report generation. Natural language generation metrics have limited clinical relevance. Clinical efficacy (CE) metrics evaluate important medical findings, but focus mainly on presence and cover only a limited set of entities. Due to heavy reliance on manual annotations, it is difficult for CE metrics to extend clinical entities or attributes. In clinical practice, radiology reports serve as a medium for information transfer. Clinicians use them to perform downstream diagnostic tasks without directly inspecting images. Based on this insight, we propose ReportQA, a clinical-related and flexible radiology report evaluation framework, supporting detailed quantitative analysis of radiology report generation systems. We first collect datasets covering multiple imaging modalities and anatomical regions. We then construct knowledge trees of clinical entities and attributes with radiologist guidance, and use large language models (LLMs) to extract structured information from raw reports. Next, we generate QA pairs from predefined templates and apply quality control through self-filtering and report-based filtering. During evaluation, the report is treated as context, and an LLM acts as a judge model to answer the QA pairs. Based on the resulting QA accuracy, we introduce QAScore metric. Compared with existing metrics, QAScore shows better alignment with radiologist judgments. Experiments on multiple state-of-the-art vision-language models reveal that current report-based inference paradigms struggle to learn fine-grained clinical representations and exhibit strong negative prior biases. In contrast, question-driven inference provides a more effective alternative. For reproducibility and extensibility, we release the knowledge trees, structured reports, and QA pairs, along with the pipeline code for QA construction and evaluation.

Large language models (LLMs) frequently generate non-factual content, known as hallucinations. Existing retrieval-augmented-based hallucination detection approaches typically address this by framing it as a classification task, evaluating hallucinations based on their consistency with retrieved evidence. However, this approach usually lacks detailed explanations for these evaluations and does not assess the reliability of these explanations. Furthermore, deficiencies in retrieval systems can lead to irrelevant or partially relevant evidence retrieval, impairing the detection process. Moreover, while real-world hallucination detection requires analyzing multiple pieces of evidence, current systems usually treat all evidence uniformly without considering its relevance to the content. To address these challenges, we introduce Halu-J, a critique-based hallucination judge with 7 billion parameters. Halu-J enhances hallucination detection by selecting pertinent evidence and providing detailed critiques. Our experiments indicate that Halu-J outperforms GPT-4o in multiple-evidence hallucination detection and matches its capability in critique generation and evidence selection. We also introduce ME-FEVER, a new dataset designed for multiple-evidence hallucination detection. Our code and dataset can be found in https://github.com/GAIR-NLP/factool .

We study the problem of detecting the correlation between two Gaussian databases XinR^{ntimes d} and Y^{ntimes d}, each composed of n users with d features. This problem is relevant in the analysis of social media, computational biology, etc. We formulate this as a hypothesis testing problem: under the null hypothesis, these two databases are statistically independent. Under the alternative, however, there exists an unknown permutation sigma over the set of n users (or, row permutation), such that X is rho-correlated with Y^sigma, a permuted version of Y. We determine sharp thresholds at which optimal testing exhibits a phase transition, depending on the asymptotic regime of n and d. Specifically, we prove that if rho^2dto0, as dtoinfty, then weak detection (performing slightly better than random guessing) is statistically impossible, irrespectively of the value of n. This compliments the performance of a simple test that thresholds the sum all entries of X^TY. Furthermore, when d is fixed, we prove that strong detection (vanishing error probability) is impossible for any rho<rho^star, where rho^star is an explicit function of d, while weak detection is again impossible as long as rho^2dto0. These results close significant gaps in current recent related studies.

RAG (Retrieval-Augmented Generation) systems and web agents are increasingly evaluated on multi-hop deep search tasks, yet current practice suffers from two major limitations. First, most benchmarks leak the reasoning path in the question text, allowing models to follow surface cues rather than discover reasoning chains autonomously. Second, evaluation is typically reduced to a single pass rate, which collapses diverse behaviours into one score and obscures whether failures stem from inadequate search, poor knowledge use, or inappropriate refusal. To address these issues, we present WebDetective, a benchmark of hint-free multi-hop questions paired with a controlled Wikipedia sandbox that ensures full traceability of model actions, and a holistic evaluation framework that separates search sufficiency, knowledge utilisation, and refusal behaviour. Our evaluation of 25 state-of-the-art models reveals systematic weaknesses across all architectures: models struggle with knowledge utilisation despite having sufficient evidence and demonstrate near-absent appropriate refusal when evidence is lacking. These patterns expose a fundamental gap: today's systems excel at executing given reasoning paths but fail when required to discover them. We develop an agentic workflow, EvidenceLoop, that explicitly targets the challenges our benchmark identifies, incorporating verification loops and systematic evidence tracking that improve both search and synthesis capabilities. This baseline demonstrates that WebDetective's diagnostic framework can guide concrete architectural improvements, establishing our benchmark as a critical tool for developing genuinely autonomous reasoning systems rather than pattern-following agents.

In 2023, a New York judge sanctioned two attorneys in Mata v. Avianca for filing a brief with hallucinated citations generated by ChatGPT. Such failures are largely caught by database lookups; the harder problem is detecting citations that point to real cases but do not support the propositions for which they are offered -- a failure mode that existing evaluations of LLMs for legal use cases largely overlook. In this paper, we study proposition-level citation support verification through controlled perturbations of real legal citations obtained from two legal corpora, either replacing the cited case or changing only the pinpoint page within the same case. We evaluate fourteen model configurations on the resulting examples. Models catch 93-100% of wrong-case corruptions. They catch only 37-61% of wrong-pinpoint corruptions on court opinions and 52-83% on legal briefs. When models fail to catch wrong-pinpoint corruptions, they accept the citation based on topical overlap rather than page-level support. Scale and extended reasoning narrow the gap but do not close it: GPT-5.4 with high reasoning effort still misses 40% of pinpoint mismatches on court opinions and 18% on briefs. Prompting the model to verify support at the cited page improves recall, but it also raises the false positive rate. Recognizing the right legal topic and verifying support for the cited proposition are distinct capabilities, and current models conflate them.

Evaluating the truthfulness of online content is critical for combating misinformation. This study examines the efficiency and effectiveness of crowdsourced truthfulness assessments through a comparative analysis of two approaches: one involving full-length webpages as evidence for each claim, and another using summaries for each evidence document generated with a large language model. Using an A/B testing setting, we engage a diverse pool of participants tasked with evaluating the truthfulness of statements under these conditions. Our analysis explores both the quality of assessments and the behavioral patterns of participants. The results reveal that relying on summarized evidence offers comparable accuracy and error metrics to the Standard modality while significantly improving efficiency. Workers in the Summary setting complete a significantly higher number of assessments, reducing task duration and costs. Additionally, the Summary modality maximizes internal agreement and maintains consistent reliance on and perceived usefulness of evidence, demonstrating its potential to streamline large-scale truthfulness evaluations.

Deep research agents are increasingly evaluated on their ability to search for evidence, reason over retrieved sources, and produce grounded answers. Existing browsing benchmarks, however, largely assume that the user's query and the supporting evidence are written in the same language, leaving open whether agentic search systems can operate when relevant evidence appears in another language. We introduce XBCP (Cross-lingual BrowseComp-Plus), a controlled benchmark that preserves the English question-and-answer space of BrowseComp-Plus but varies the languages of the supporting documents. XBCP instantiates two complementary settings: in the cross-lingual setting, each query is paired with evidence in a single assigned language. In the multilingual setting, the full evidence corpus is distributed equally and randomly across 12 languages spanning high-resource and low-resource regimes. We evaluate four deep research agents using sparse and dense multilingual retrievers, measuring answer accuracy, evidence recall, search behavior, calibration, citation fidelity, and oracle retrieval. Results reveal substantial degradation when evidence is translated. Even strong, dense retrievers lose evidence recall, and agents become less calibrated and cite evidence less reliably. Notably, accuracy remains lower even when all gold evidence is supplied directly. These findings suggest that cross-lingual deep research exposes both retrieval failures and an independent, agent-side difficulty in integrating language-mismatched evidence.

Users increasingly rely on Large Language Models (LLMs) for Deep Research, using them to synthesize diverse sources into structured reports that support understanding and action. In this context, the practical reliability of such reports hinges on logical quality: whether the report's claims and arguments are explicitly supported and can be trusted as a basis for downstream use, rather than merely appearing fluent or informative. However, current evaluation frameworks largely overlook this requirement. To bridge this gap, we introduce ReportLogic, a benchmark that quantifies report-level logical quality through a reader-centric lens of auditability. Specifically, ReportLogic adopts a hierarchical taxonomy that evaluates whether readers can (1) trace an on-topic report structure with a unified analytical arc (Macro-Logic), (2) understand the progression with necessary context (Expositional-Logic), and (3) verify conclusions via explicit claim--support (Structural-Logic). Based on this taxonomy, we construct a human-annotated rubric-guided dataset and train an open-source LogicJudge for scalable evaluation. We further evaluate judge robustness via adversarial attacks, showing that off-the-shelf LLM judges are frequently influenced by superficial cues (e.g., verbosity), and reasoning modes can mask broken support relations. Overall, our results provide actionable guidance for building more robust logic evaluators and improving the logical reliability of LLM-generated reports.

We explore whether Large Language Models (LLMs) are capable of logical reasoning with distorted facts, which we call Deduction under Perturbed Evidence (DUPE). DUPE presents a unique challenge to LLMs since they typically rely on their parameters, which encode mostly accurate information, to reason and make inferences. However, in DUPE, LLMs must reason over manipulated or falsified evidence present in their prompts, which can result in false conclusions that are valid only under the manipulated evidence. Our goal with DUPE is to determine whether LLMs can arrive at these false conclusions and identify whether the dominant factor influencing the deduction process is the encoded data in the parameters or the manipulated evidence in the prompts. To evaluate the DUPE capabilities of LLMs, we create a DUPEd version of the StrategyQA dataset, where facts are manipulated to reverse the answer to the question. Our findings show that even the most advanced GPT models struggle to reason on manipulated facts - showcasing poor DUPE skills - with accuracy dropping by 45% compared to the original dataset. We also investigate prompt settings inspired from student simulation models, which mitigate the accuracy drop to some extent. Our findings have practical implications for understanding the performance of LLMs in real-world applications such as student simulation models that involve reasoning over inaccurate information.

Multimodal Large Language Models (MLLMs) have significantly advanced document understanding, yet current Doc-VQA evaluations score only the final answer and leave the supporting evidence unchecked. This answer-only approach masks a critical failure mode: a model can land on the correct answer while grounding it in the wrong passage -- a critical risk in high-stakes domains like law, finance, and medicine, where every conclusion must be traceable to a specific source region. To address this, we introduce CiteVQA, a benchmark that requires models to return element-level bounding-box citations alongside each answer, evaluating both jointly. CiteVQA comprises 1,897 questions across 711 PDFs spanning seven domains and two languages, averaging 40.6 pages per document. To ensure fidelity and scalability, the ground-truth citations are generated by an automated pipeline-which identifies crucial evidence via masking ablation-and are subsequently validated through expert review. At the core of our evaluation is Strict Attributed Accuracy (SAA), which credits a prediction only when the answer and the cited region are both correct. Auditing 20 MLLMs reveals a pervasive Attribution Hallucination: models frequently produce the right answer while citing the wrong region. The strongest system (Gemini-3.1-Pro-Preview) achieves an SAA of only 76.0, and the strongest open-source MLLM reaches just 22.5. Ultimately, towards trustworthy document intelligence, CiteVQA exposes a reliability gap that answer-only evaluations overlook, providing the instrumentation needed to close it. Our repository is available at https://github.com/opendatalab/CiteVQA.

Large language models (LLMs) are increasingly being used for complex research tasks such as literature review, idea generation, and scientific paper analysis, yet their ability to truly understand and process the intricate relationships within complex research papers, such as the logical links between claims and supporting evidence remains largely unexplored. In this study, we present CLAIM-BENCH, a comprehensive benchmark for evaluating LLMs' capabilities in scientific claim-evidence extraction and validation, a task that reflects deeper comprehension of scientific argumentation. We systematically compare three approaches which are inspired by divide and conquer approaches, across six diverse LLMs, highlighting model-specific strengths and weaknesses in scientific comprehension. Through evaluation involving over 300 claim-evidence pairs across multiple research domains, we reveal significant limitations in LLMs' ability to process complex scientific content. Our results demonstrate that closed-source models like GPT-4 and Claude consistently outperform open-source counterparts in precision and recall across claim-evidence identification tasks. Furthermore, strategically designed three-pass and one-by-one prompting approaches significantly improve LLMs' abilities to accurately link dispersed evidence with claims, although this comes at increased computational cost. CLAIM-BENCH sets a new standard for evaluating scientific comprehension in LLMs, offering both a diagnostic tool and a path forward for building systems capable of deeper, more reliable reasoning across full-length papers.

Meta-analysis is a demanding form of evidence synthesis that combines literature retrieval, PI/ECO-guided study selection, and statistical aggregation. Its structured, verifiable workflow makes it an ideal substrate for evaluating systematic scientific reasoning, yet existing benchmarks lack ground truth across the full retrieval-screening-synthesis pipeline. We introduce MetaSyn, a dataset of 442 expert-curated meta-analyses from Nature Portfolio journals. Each entry pairs a research question with PI/ECO criteria, a retrieval corpus of 140k PubMed articles, verified positive studies, hard negatives that are topically similar but PI/ECO-ineligible, and complete search strategies and date bounds. Benchmarking twelve pipeline configurations (nine RAG variants and a protocol-driven agent) reveals a critical screening bottleneck: despite a retrieval ceiling of 90.9% recall at K=200, no system recovers more than 52.7% of ground-truth included literature. Current LLMs fail to reliably separate eligible studies from PI/ECO-failing distractors in pools of comparable topical relevance. Stage-attributed metrics capture where systems succeed and fail; a single end-to-end score does not.

We introduce a boosting algorithm to pre-process data for fairness. Starting from an initial fair but inaccurate distribution, our approach shifts towards better data fitting while still ensuring a minimal fairness guarantee. To do so, it learns the sufficient statistics of an exponential family with boosting-compliant convergence. Importantly, we are able to theoretically prove that the learned distribution will have a representation rate and statistical rate data fairness guarantee. Unlike recent optimization based pre-processing methods, our approach can be easily adapted for continuous domain features. Furthermore, when the weak learners are specified to be decision trees, the sufficient statistics of the learned distribution can be examined to provide clues on sources of (un)fairness. Empirical results are present to display the quality of result on real-world data.

Randomized controlled trials (RCTs) are the benchmark for causal inference, yet field implementation can deviate. We here present a remote audit - a design-based, preregistrable diagnostic that uses only pre-treatment satellite imagery to test whether assignment is independent of local conditions. The conditional randomization test of the remote audit evaluates whether treatment assignment is more predictable from pre-treatment satellite features than expected under the experiment's registered mechanism, providing a finite-sample valid, design-based diagnostic that requires no parametric assumptions. The procedure is finite-sample valid, honors blocks and clusters, and controls multiplicity across image models and resolutions via a max-statistic. We illustrate with two RCTs: Uganda's Youth Opportunities Program, where the audit corroborates randomization and flags selection and missing-data risks; and a school-based trial in Bangladesh, where assignment is highly predictable from pre-treatment features relative to the stated design, consistent with independent concerns about irregularities. Remote audits complement balance tests, lower early-stage costs, and enable rapid design checks when baseline surveys are expensive or infeasible.

Retrieval-Augmented Generation (RAG) grounds Large Language Models (LLMs) in external knowledge but often suffers from flat context representations and stateless retrieval, leading to unstable performance. We propose Stateful Evidence-Driven RAG with Iterative Reasoning, a framework that models question answering as a progressive evidence accumulation process. Retrieved documents are converted into structured reasoning units with explicit relevance and confidence signals and maintained in a persistent evidence pool capturing both supportive and non-supportive information. The framework performs evidence-driven deficiency analysis to identify gaps and conflicts and iteratively refines queries to guide subsequent retrieval. This iterative reasoning process enables stable evidence aggregation and improves robustness to noisy retrieval. Experiments on multiple question answering benchmarks demonstrate consistent improvements over standard RAG and multi-step baselines, while effectively accumulating high-quality evidence and maintaining stable performance under substantial retrieval noise.

Recent advances in probabilistic modelling have led to a large number of simulation-based inference algorithms which do not require numerical evaluation of likelihoods. However, a public benchmark with appropriate performance metrics for such 'likelihood-free' algorithms has been lacking. This has made it difficult to compare algorithms and identify their strengths and weaknesses. We set out to fill this gap: We provide a benchmark with inference tasks and suitable performance metrics, with an initial selection of algorithms including recent approaches employing neural networks and classical Approximate Bayesian Computation methods. We found that the choice of performance metric is critical, that even state-of-the-art algorithms have substantial room for improvement, and that sequential estimation improves sample efficiency. Neural network-based approaches generally exhibit better performance, but there is no uniformly best algorithm. We provide practical advice and highlight the potential of the benchmark to diagnose problems and improve algorithms. The results can be explored interactively on a companion website. All code is open source, making it possible to contribute further benchmark tasks and inference algorithms.

Clinical protocol-execution tasks -- checking a lab value, applying a threshold, placing a correctly structured FHIR order -- are natural candidates for RL from world feedback: once clinical SMEs encode decision logic into a verifier, that verifier grades unlimited rollouts without per-episode annotation. But applying RL requires a sound feedback channel and sufficient base capability. We audit MedAgentBench v1/v2, find a 41.7\% silent-finish ceiling that makes inaction the RL dominant strategy, and construct MedAgentBench-v3 (MAB-v3) (508 tasks, 8.9\% ceiling). Training Qwen3-8B exposes two structural barriers: a capability ceiling (10/20 task types have 0\% base performance, zero gradient) and a format-knowledge barrier (3/20 types require exact clinical codes undiscoverable by exploration). Pure RL reaches 18.2\% pass@1 vs.\ 34.1\% for rule-based SFT; the 15.9~pp gap is attributable entirely to these barriers. A decision/format-knowledge/lookup taxonomy predicts RL learnability and prescribes the fix: SFT to inject codes, RL to learn conditionals.

Standard Retrieval-Augmented Generation (RAG) systems predominantly rely on semantic relevance as a proxy for utility. However, this assumption collapses in realistic decision-making scenarios where user queries are laden with cognitive biases, such as false premises or confirmation bias. In such cases, maximizing relevance paradoxically promotes the retrieval of sycophantic evidence that reinforces hallucinations, a critical failure we term the ``Relevance-Robustness Gap''. To bridge this gap, we propose CoRM-RAG (Counterfactual Risk Minimization for RAG), a framework that aligns retrieval with decision safety rather than mere similarity. Grounded in causal intervention, we introduce a Cognitive Perturbation Protocol to simulate user biases during training, which is then distilled into a lightweight Evidence Critic. This scoring module learns to identify documents that possess sufficient evidential strength to steer the model toward correctness despite adversarial query perturbations. Extensive experiments on decision-making benchmarks demonstrate that CoRM-RAG significantly outperforms strong dense retrievers and LLM-based rerankers in adversarial settings, while enabling effective risk-aware abstention through reliable robustness scoring. Our code is available at https://github.com/PeiYangLiu/CoRM-RAG.git.

The rapid propagation of misinformation poses substantial risks to public interest. To combat misinformation, large language models (LLMs) are adapted to automatically verify claim credibility. Nevertheless, existing methods heavily rely on the embedded knowledge within LLMs and / or black-box APIs for evidence collection, leading to subpar performance with smaller LLMs or upon unreliable context. In this paper, we propose retrieval augmented fact verification through the synthesis of contrasting arguments (RAFTS). Upon input claims, RAFTS starts with evidence retrieval, where we design a retrieval pipeline to collect and re-rank relevant documents from verifiable sources. Then, RAFTS forms contrastive arguments (i.e., supporting or refuting) conditioned on the retrieved evidence. In addition, RAFTS leverages an embedding model to identify informative demonstrations, followed by in-context prompting to generate the prediction and explanation. Our method effectively retrieves relevant documents as evidence and evaluates arguments from varying perspectives, incorporating nuanced information for fine-grained decision-making. Combined with informative in-context examples as prior, RAFTS achieves significant improvements to supervised and LLM baselines without complex prompts. We demonstrate the effectiveness of our method through extensive experiments, where RAFTS can outperform GPT-based methods with a significantly smaller 7B LLM.

Recent progress in multimodal large language models (MLLMs) has demonstrated promising performance on medical benchmarks and in preliminary trials as clinical assistants. Yet, our pilot audit of diagnostic cases uncovers a critical failure mode: instability in early evidence interpretation precedes hallucination, creating branching reasoning trajectories that cascade into globally inconsistent conclusions. This highlights the need for clinical reasoning agents that constrain stochasticity and hallucination while producing auditable decision flows. We introduce MedMMV, a controllable multimodal multi-agent framework for reliable and verifiable clinical reasoning. MedMMV stabilizes reasoning through diversified short rollouts, grounds intermediate steps in a structured evidence graph under the supervision of a Hallucination Detector, and aggregates candidate paths with a Combined Uncertainty scorer. On six medical benchmarks, MedMMV improves accuracy by up to 12.7% and, more critically, demonstrates superior reliability. Blind physician evaluations confirm that MedMMV substantially increases reasoning truthfulness without sacrificing informational content. By controlling instability through a verifiable, multi-agent process, our framework provides a robust path toward deploying trustworthy AI systems in high-stakes domains like clinical decision support.

Finding relevant literature underpins the practice of evidence-based medicine. From 2014 to 2016, TREC conducted a clinical decision support track, wherein participants were tasked with finding articles relevant to clinical questions posed by physicians. In total, 87 teams have participated over the past three years, generating 395 runs. During this period, each team has trialled a variety of methods. While there was significant overlap in the methods employed by different teams, the results were varied. Due to the diversity of the platforms used, the results arising from the different techniques are not directly comparable, reducing the ability to build on previous work. By using a stable platform, we have been able to compare different document and query processing techniques, allowing us to experiment with different search parameters. We have used our system to reproduce leading teams runs, and compare the results obtained. By benchmarking our indexing and search techniques, we can statistically test a variety of hypotheses, paving the way for further research.

Evaluating whether multimodal large language models truly understand long-form scientific papers remains challenging: answer-only metrics and synthetic "Needle-In-A-Haystack" tests often reward answer matching without requiring a causal, evidence-linked reasoning trace in the document. We propose the "Fish-in-the-Ocean" (FITO) paradigm, which requires models to construct explicit cross-modal evidence chains within native scientific documents. To operationalize FITO, we build SIN-Data, a scientific interleaved corpus that preserves the native interleaving of text and figures. On top of it, we construct SIN-Bench with four progressive tasks covering evidence discovery (SIN-Find), hypothesis verification (SIN-Verify), grounded QA (SIN-QA), and evidence-anchored synthesis (SIN-Summary). We further introduce "No Evidence, No Score", scoring predictions when grounded to verifiable anchors and diagnosing evidence quality via matching, relevance, and logic. Experiments on eight MLLMs show that grounding is the primary bottleneck: Gemini-3-pro achieves the best average overall score (0.573), while GPT-5 attains the highest SIN-QA answer accuracy (0.767) but underperforms on evidence-aligned overall scores, exposing a gap between correctness and traceable support.

Retrieval-augmented generation (RAG) under a fixed reader-context budget forces a selection problem: of the evidence retrieved, only a fraction can be shown to the reader. We argue that document recall -- the standard retrieval metric -- is the wrong quantity to optimize in this regime, and we make two contributions. First, as a general contribution, we introduce answer-in-context, a diagnostic that measures whether a gold answer survives as a contiguous span in the packed reader context (not the retrieved set). It predicts answer F1 better than recall (r=0.39-0.55 vs. about 0.31), separates answer quality roughly five-fold (0.60 vs. 0.12 on HotpotQA), and carries information beyond retrieval: it adds Delta R squared=0.17 over recall and shows a 4.6x EM gap even among questions where all gold was retrieved. We also confirm it interventionally: on 2WikiMultiHopQA a packing change that raises coverage but not answer-in-context yields no accuracy gain. Second, as a conditional contribution, we cast reader-context construction as budgeted monotone submodular maximization and build a packer that jointly optimizes relevance, query coverage, representativeness, and diversity. On HotpotQA with a 160-token budget and a 3B reader it beats a strong focused heuristic, MMR, and naive packing -- by up to +5.1 F1 at equal-or-lower token cost, across three seeds. Crucially, we map the scope of this win honestly: it requires the conjunction of (i) multi-hop complementary structure, (ii) retrieval that surfaces the evidence, (iii) a binding but not extreme budget, and (iv) a reader weak enough that evidence density, not reading capacity, is the bottleneck. A quantization-controlled reader-scale ladder (3B to 7B to 14B) shows the edge over the heuristic is absorbed by 7B and significantly reverses by 14B, while the diagnostic explains every boundary with a single variable.

Recent Large Reasoning Models (LRMs), such as DeepSeek-R1 and OpenAI o1, have demonstrated strong performance gains by scaling up the length of Chain-of-Thought (CoT) reasoning during inference. However, a growing concern lies in their tendency to produce excessively long reasoning traces, which are often filled with redundant content (e.g., repeated definitions), over-analysis of simple problems, and superficial exploration of multiple reasoning paths for harder tasks. This inefficiency introduces significant challenges for training, inference, and real-world deployment (e.g., in agent-based systems), where token economy is critical. In this survey, we provide a comprehensive overview of recent efforts aimed at improving reasoning efficiency in LRMs, with a particular focus on the unique challenges that arise in this new paradigm. We identify common patterns of inefficiency, examine methods proposed across the LRM lifecycle, i.e., from pretraining to inference, and discuss promising future directions for research. To support ongoing development, we also maintain a real-time GitHub repository tracking recent progress in the field. We hope this survey serves as a foundation for further exploration and inspires innovation in this rapidly evolving area.

Reinforcement learning enables Agentic RAG systems to learn multi-turn search from verifiable outcome rewards, but all- zero rollout groups provide no comparative signal and may hide useful search behavior. We present EviBack, an evidence- constrained Teacher backoff that supplies auxiliary super- vision to such groups while preserving verifiable Actor re- wards. It separates evidence assessment from answer refine- ment, preventing reference answers from overriding evidence- insufficiency judgments. A fully automated, end-to-end GPT- 5.5-assisted APE pipeline starts from a manually authored single-prompt dual-task Teacher, automatically partitions and labels rollout data, and performs ablation, task decomposition, evaluation, and selection to produce a gated two-stage Teacher. Compared with the manual design, the resulting Teacher im- proves downstream F1 and valid-answer rate while reduc- ing search, duplicate queries, and forced termination. Across seven open-domain QA benchmarks and three Qwen3 scales, EviBack improves F1 over Search-R1 and raises both single- and multi-hop macro F1. We guarantee that the code will be made publicly available at a later stage.

The task of mixture proportion estimation (MPE) is to estimate the weight of a component distribution in a mixture, given observations from both the component and mixture. Previous work on MPE adopts the irreducibility assumption, which ensures identifiablity of the mixture proportion. In this paper, we propose a more general sufficient condition that accommodates several settings of interest where irreducibility does not hold. We further present a resampling-based meta-algorithm that takes any existing MPE algorithm designed to work under irreducibility and adapts it to work under our more general condition. Our approach empirically exhibits improved estimation performance relative to baseline methods and to a recently proposed regrouping-based algorithm.

Majority voting over multiple LLM attempts improves mathematical reasoning, but correlated errors limit the effective sample size. A natural fix is to assign different reasoning strategies to different voters. The approach, Diverse Prompt Mixer, is tested on the AIMO 3 competition: 3 models, 23+ experiments, 50 IMO-level problems, one H100 80 GB, 5-hour limit. Every prompt-level intervention fails. High-temperature sampling already decorrelates errors; weaker strategies reduce accuracy more than they reduce correlation. Across an 8-point capability gap at equal N=8 and every optimization tested, model capability dominates. The gap between the best majority-vote score (42/50) and pass@20 (~45.5) is selection loss, not prompt loss. A verifier-based selector could close it. Prompt engineering cannot.

Background: Agent skills are increasingly deployed as modular, reusable capability units in AI agent systems. Medical research agent skills require safeguards beyond general-purpose evaluation, including scientific integrity, methodological validity, reproducibility, and boundary safety. This study developed and preliminarily evaluated a domain-specific audit framework for medical research agent skills, with a focus on reliability against expert review. Methods: We developed MedSkillAudit (skill-auditor@1.0), a layered framework assessing skill release readiness before deployment. We evaluated 75 skills across five medical research categories (15 per category). Two experts independently assigned a quality score (0-100), an ordinal release disposition (Production Ready / Limited Release / Beta Only / Reject), and a high-risk failure flag. System-expert agreement was quantified using ICC(2,1) and linearly weighted Cohen's kappa, benchmarked against the human inter-rater baseline. Results: The mean consensus quality score was 72.4 (SD = 13.0); 57.3% of skills fell below the Limited Release threshold. MedSkillAudit achieved ICC(2,1) = 0.449 (95% CI: 0.250-0.610), exceeding the human inter-rater ICC of 0.300. System-consensus score divergence (SD = 9.5) was smaller than inter-expert divergence (SD = 12.4), with no directional bias (Wilcoxon p = 0.613). Protocol Design showed the strongest category-level agreement (ICC = 0.551); Academic Writing showed a negative ICC (-0.567), reflecting a structural rubric-expert mismatch. Conclusions: Domain-specific pre-deployment audit may provide a practical foundation for governing medical research agent skills, complementing general-purpose quality checks with structured audit workflows tailored to scientific use cases.

Explanations for AI models in high-stakes domains like medicine often lack verifiability, which can hinder trust. To address this, we propose an interactive agent that produces explanations through an auditable sequence of actions. The agent learns a policy to strategically seek external visual evidence to support its diagnostic reasoning. This policy is optimized using reinforcement learning, resulting in a model that is both efficient and generalizable. Our experiments show that this action-based reasoning process significantly improves calibrated accuracy, reducing the Brier score by 18\% compared to a non-interactive baseline. To validate the faithfulness of the agent's explanations, we introduce a causal intervention method. By masking the visual evidence the agent chooses to use, we observe a measurable degradation in its performance (DeltaBrier=+0.029), confirming that the evidence is integral to its decision-making process. Our work provides a practical framework for building AI systems with verifiable and faithful reasoning capabilities.

Deep Research agents extend LLM-based assistants into long-horizon workflows involving planning, retrieval, evidence synthesis, and report generation, yet their reliability in open information environments remains underexplored. A key concern is whether apparently credible but factually misleading knowledge encountered in such environments can propagate through these workflows and be adopted as false conclusions in final reports. To study this failure mode, we introduce MisKnow-Agent, a framework for constructing and validating misleading knowledge for Deep Research tasks. MisKnow-Agent generates misleading instances with controllable authority levels and styles, yielding 5,933 quality-controlled instances built on DeepResearch Benchmark tasks. Extensive experiments across open-source and closed-source Deep Research agents show that even limited exposure to misleading knowledge can induce false-conclusion adoption in final reports, revealing a broad reliability vulnerability in current Deep Research agents. Although search-enabled verifier models consistently identify the retained instances as misleading during focused corpus validation, the same instances can still be adopted during long-horizon research, revealing a disconnect between focused verification and workflow-level evidence use. Finally, we evaluate pre- and post-research defenses, both individually and in combination, finding that all three configurations mitigate but do not fully prevent false-conclusion adoption. Our findings suggest that reliable Deep Research requires evidence verification and correction capabilities at both the model and framework levels, beyond improvements in planning, retrieval, evidence integration, or report-generation abilities.

Misinformation and disinformation demand fact checking that goes beyond simple evidence-based reasoning. Existing benchmarks fall short: they are largely single modality (text-only), span short time horizons, use shallow evidence, cover domains unevenly, and often omit full articles -- obscuring models' real-world capability. We present MMM-Fact, a large-scale benchmark of 125,449 fact-checked statements (1995--2025) across multiple domains, each paired with the full fact-check article and multimodal evidence (text, images, videos, tables) from four fact-checking sites and one news outlet. To reflect verification effort, each statement is tagged with a retrieval-difficulty tier -- Basic (1--5 sources), Intermediate (6--10), and Advanced (>10) -- supporting fairness-aware evaluation for multi-step, cross-modal reasoning. The dataset adopts a three-class veracity scheme (true/false/not enough information) and enables tasks in veracity prediction, explainable fact-checking, complex evidence aggregation, and longitudinal analysis. Baselines with mainstream LLMs show MMM-Fact is markedly harder than prior resources, with performance degrading as evidence complexity rises. MMM-Fact offers a realistic, scalable benchmark for transparent, reliable, multimodal fact-checking.

We consider the problem of performing Bayesian inference in probabilistic models where observations are accompanied by uncertainty, referred to as "uncertain evidence." We explore how to interpret uncertain evidence, and by extension the importance of proper interpretation as it pertains to inference about latent variables. We consider a recently-proposed method "distributional evidence" as well as revisit two older methods: Jeffrey's rule and virtual evidence. We devise guidelines on how to account for uncertain evidence and we provide new insights, particularly regarding consistency. To showcase the impact of different interpretations of the same uncertain evidence, we carry out experiments in which one interpretation is defined as "correct." We then compare inference results from each different interpretation illustrating the importance of careful consideration of uncertain evidence.

Multimodal Large Language Models (MLLMs) are prone to hallucination as their generation preferences are insufficiently calibrated to visual evidence, causing them to fall back on linguistic priors, rather than faithful grounding. In this work, we start from an empirical observation: when query-relevant visual evidence is explicitly strengthened using the model's own attention, generation becomes more accurate, suggesting that many failures do not arise solely from missing perception, but from an insufficient tendency to trust the evidence the model has already attended to. Motivated by this finding, we propose Oriented Pickup Preference Optimization (OPPO), an evidence-aware alignment objective that learns preferences over the strength of visual evidence, rather than only response quality. Concretely, OPPO contrasts the same faithful response under stronger, anchored, weaker-evidence views, turning naive visual preference into ordered visual-evidence alignment. We further combine this objective with fine-grained span-level and token-level regularization to stabilize the training. Besides, we provide a theoretical analysis showing that ordered evidence margins induce a positive lower bound on local visual sensitivity. Extensive evaluations across hallucination and general-purpose benchmarks demonstrate that OPPO consistently outperforms baseline methods.

With the widespread adoption of large language models (LLMs), hallucinations, which are non-factual fabrications in model outputs, have become serious concerns. Reasoning capabilities have received attention as a self-verification process to improve output reliability. However, the effect of reasoning within a closed system where LLMs cannot rely on external tools or knowledge has yet to be clarified. We therefore conduct experiments under strict constraints (recommending peer-reviewed journal articles in computer science) to examine the effect of reasoning across multiple models (GPT-5.2 and Gemini 3 Flash). Our results reveal a problematic trade-off between constraint compliance and factual accuracy. Non-reasoning models exhibit high constraint violation rates (66-75%) but maintain factual accuracy, while reasoning models reduce violations (13-26%) but systematically distort known facts to satisfy constraints and increase complete fabrication. This trade-off pattern is consistent across both models despite different architectures, indicating a fundamental limitation of reasoning. Furthermore, reasoning does not uniformly improve output authenticity: effects diverge by model, reflecting different allocations of the compliance-truthfulness trade-off. These findings challenge the assumption that reasoning universally improves reliability: reasoning models trade honest constraint violations for detection-resistant distortions.

Augmenting LLMs with context leads to improved performance across many applications. Despite much research on Retrieval Augmented Generation (RAG) systems, an open question is whether errors arise because LLMs fail to utilize the context from retrieval or the context itself is insufficient to answer the query. To shed light on this, we develop a new notion of sufficient context, along with a way to classify instances that have enough information to answer the query. We then use sufficient context to analyze several models and datasets. By stratifying errors based on context sufficiency, we find that proprietary LLMs (Gemini, GPT, Claude) excel at answering queries when the context is sufficient, but often output incorrect answers instead of abstaining when the context is not. On the other hand, open-source LLMs (Llama, Mistral, Gemma) hallucinate or abstain often, even with sufficient context. We further categorize cases when the context is useful, and improves accuracy, even though it does not fully answer the query and the model errs without the context. Building on our findings, we explore ways to reduce hallucinations in RAG systems, including a new selective generation method that leverages sufficient context information for guided abstention. Our method improves the fraction of correct answers among times where the model responds by 2-10% for Gemini, GPT, and Gemma.

Generalist foundation models such as GPT-4 have displayed surprising capabilities in a wide variety of domains and tasks. Yet, there is a prevalent assumption that they cannot match specialist capabilities of fine-tuned models. For example, most explorations to date on medical competency benchmarks have leveraged domain-specific training, as exemplified by efforts on BioGPT and Med-PaLM. We build on a prior study of GPT-4's capabilities on medical challenge benchmarks in the absence of special training. Rather than using simple prompting to highlight the model's out-of-the-box capabilities, we perform a systematic exploration of prompt engineering. We find that prompting innovation can unlock deeper specialist capabilities and show that GPT-4 easily tops prior leading results for medical benchmarks. The prompting methods we explore are general purpose, and make no specific use of domain expertise, removing the need for expert-curated content. Our experimental design carefully controls for overfitting during the prompt engineering process. We introduce Medprompt, based on a composition of several prompting strategies. With Medprompt, GPT-4 achieves state-of-the-art results on all nine of the benchmark datasets in the MultiMedQA suite. The method outperforms leading specialist models such as Med-PaLM 2 by a significant margin with an order of magnitude fewer calls to the model. Steering GPT-4 with Medprompt achieves a 27% reduction in error rate on the MedQA dataset over the best methods to date achieved with specialist models and surpasses a score of 90% for the first time. Beyond medical problems, we show the power of Medprompt to generalize to other domains and provide evidence for the broad applicability of the approach via studies of the strategy on exams in electrical engineering, machine learning, philosophy, accounting, law, nursing, and clinical psychology.

This study investigates GPT-4's assessment of its performance in healthcare applications. A simple prompting technique was used to prompt the LLM with questions taken from the United States Medical Licensing Examination (USMLE) questionnaire and it was tasked to evaluate its confidence score before posing the question and after asking the question. The questionnaire was categorized into two groups-questions with feedback (WF) and questions with no feedback(NF) post-question. The model was asked to provide absolute and relative confidence scores before and after each question. The experimental findings were analyzed using statistical tools to study the variability of confidence in WF and NF groups. Additionally, a sequential analysis was conducted to observe the performance variation for the WF and NF groups. Results indicate that feedback influences relative confidence but doesn't consistently increase or decrease it. Understanding the performance of LLM is paramount in exploring its utility in sensitive areas like healthcare. This study contributes to the ongoing discourse on the reliability of AI, particularly of LLMs like GPT-4, within healthcare, offering insights into how feedback mechanisms might be optimized to enhance AI-assisted medical education and decision support.

The proliferation of online misinformation has posed significant threats to public interest. While numerous online users actively participate in the combat against misinformation, many of such responses can be characterized by the lack of politeness and supporting facts. As a solution, text generation approaches are proposed to automatically produce counter-misinformation responses. Nevertheless, existing methods are often trained end-to-end without leveraging external knowledge, resulting in subpar text quality and excessively repetitive responses. In this paper, we propose retrieval augmented response generation for online misinformation (RARG), which collects supporting evidence from scientific sources and generates counter-misinformation responses based on the evidences. In particular, our RARG consists of two stages: (1) evidence collection, where we design a retrieval pipeline to retrieve and rerank evidence documents using a database comprising over 1M academic articles; (2) response generation, in which we align large language models (LLMs) to generate evidence-based responses via reinforcement learning from human feedback (RLHF). We propose a reward function to maximize the utilization of the retrieved evidence while maintaining the quality of the generated text, which yields polite and factual responses that clearly refutes misinformation. To demonstrate the effectiveness of our method, we study the case of COVID-19 and perform extensive experiments with both in- and cross-domain datasets, where RARG consistently outperforms baselines by generating high-quality counter-misinformation responses.

The Evidence Lower Bound (ELBO) is a quantity that plays a key role in variational inference. It can also be used as a criterion in model selection. However, though extremely popular in practice in the variational Bayes community, there has never been a general theoretic justification for selecting based on the ELBO. In this paper, we show that the ELBO maximization strategy has strong theoretical guarantees, and is robust to model misspecification while most works rely on the assumption that one model is correctly specified. We illustrate our theoretical results by an application to the selection of the number of principal components in probabilistic PCA.

Recent research has generated hope that inference scaling could allow weaker language models to match or exceed the accuracy of stronger models, such as by repeatedly sampling solutions to a coding problem until it passes unit tests. The central thesis of this paper is that there is no free lunch for inference scaling: indefinite accuracy improvement through resampling can only be realized if the "verifier" (in this case, a set of unit tests) is perfect. When the verifier is imperfect, as it almost always is in domains such as reasoning or coding (for example, unit tests have imperfect coverage), there is a nonzero probability of false positives: incorrect solutions that pass the verifier. Resampling cannot decrease this probability, so it imposes an upper bound to the accuracy of resampling-based inference scaling even with an infinite compute budget. We find that there is a very strong correlation between the model's single-sample accuracy (i.e. accuracy without unit tests) and its false positive rate on coding benchmarks HumanEval and MBPP, whose unit tests have limited coverage. Therefore, no amount of inference scaling of weaker models can enable them to match the single-sample accuracy of a sufficiently strong model (Fig. 1a). When we consider that false positives have a negative utility compared to abstaining from producing a solution, it bends the inference scaling curve further downward. Empirically, we find that the optimal number of samples can be less than 10 under realistic assumptions (Fig. 1b). Finally, we show that beyond accuracy, false positives may have other undesirable qualities, such as poor adherence to coding style conventions.

International Classification of Diseases (ICD) coding assigns diagnosis codes to clinical documents and is essential for healthcare billing and clinical analysis. Reliable coding requires that each predicted code be supported by explicit textual evidence. However, existing public datasets provide only code labels, without evidence annotations, limiting models' ability to learn evidence-grounded predictions. In this work, we argue that dense, document-level evidence annotation is not always necessary for learning evidence-based coding. Instead, models can learn code-specific evidence patterns from local spans and use these patterns to support document-level evidence-based coding. Based on this insight, we propose Span-Centric Learning (SCL), a training framework that strengthens LLMs' coding ability at the span level and transfers this capability to full clinical documents. Specifically, we use a small set of annotated documents to supervise evidence recognition, aggregation, and code assignment, while leveraging a large collection of lightweight evidence spans to reinforce span-level reasoning. Due to their compactness, span annotations are scalable and can be further augmented through synthesis. Under the same Llama3.1-8B backbone, our approach achieves an 8.2-point improvement in macro-F1 at only 20% of the training cost of standard SFT, and provides explicit supporting evidence for each predicted code, enabling human auditing and revision.

Building upon our previous investigations of O1 replication (Part 1: Journey Learning [Qin et al., 2024] and Part 2: Distillation [Huang et al., 2024]), this work explores the potential of inference-time scaling in large language models (LLMs) for medical reasoning tasks, ranging from diagnostic decision-making to treatment planning. Through extensive experiments on medical benchmarks of varying complexity (MedQA, Medbullets, and JAMA Clinical Challenges), our investigation reveals several key insights: (1) Increasing inference time does lead to improved performance. With a modest training set of 500 samples, our model yields substantial performance improvements of 6%-11%. (2) Task complexity directly correlates with the required length of reasoning chains, confirming the necessity of extended thought processes for challenging problems. (3) The differential diagnoses generated by our model adhere to the principles of the hypothetico-deductive method, producing a list of potential conditions that may explain a patient's symptoms and systematically narrowing these possibilities by evaluating the evidence. These findings demonstrate the promising synergy between inference-time scaling and journey learning in advancing LLMs' real-world clinical reasoning capabilities.

Large language models achieve strong scores on medical benchmarks, yet these benchmarks evaluate each question in isolation, providing no measure of whether a system can distinguish clinically similar presentations requiring different interventions. We introduce MamaBench, the first counterfactual benchmark for maternal and paediatric AI: 434 expert-authored clinical narratives in 217 pairs across 371 pathologies, evaluated via the Bias Trap Rate (BTR), the conditional probability that a model fails the counterfactual given success on the base case. We propose Evidence-Anchored RAG (EA-RAG), a three-stage retrieval method that replaces aggregate similarity with an evidence coverage objective through clinical parameter extraction, coverage auditing, and contrastive sub-queries. Across eight configurations of four frontier LLMs, base accuracy overstates robust accuracy by 16-28 percentage points in every model. EA-RAG achieves 20.3% BTR and 65.0% robust accuracy on Claude Sonnet 4.6, a 5.5 percentage point BTR reduction without degrading base accuracy. The residual 20% BTR confirms that counterfactual robustness in clinical AI remains an open challenge. Keywords: counterfactual evaluation, clinical AI, maternal healthcare, retrieval-augmented generation, diagnostic robustness

Evaluating Retrieval-Augmented Generation (RAG) in large language models (LLMs) is challenging because benchmarks can quickly become stale. Questions initially requiring retrieval may become answerable from pretraining knowledge as newer models incorporate more recent information during pretraining, making it difficult to distinguish evidence-based reasoning from recall. We introduce NeoQA (News Events for Out-of-training Question Answering), a benchmark designed to address this issue. To construct NeoQA, we generated timelines and knowledge bases of fictional news events and entities along with news articles and Q\&A pairs to prevent LLMs from leveraging pretraining knowledge, ensuring that no prior evidence exists in their training data. We propose our dataset as a new platform for evaluating evidence-based question answering, as it requires LLMs to generate responses exclusively from retrieved evidence and only when sufficient evidence is available. NeoQA enables controlled evaluation across various evidence scenarios, including cases with missing or misleading details. Our findings indicate that LLMs struggle to distinguish subtle mismatches between questions and evidence, and suffer from short-cut reasoning when key information required to answer a question is missing from the evidence, underscoring key limitations in evidence-based reasoning.

Assessing whether an article supports an assertion is essential for hallucination detection and claim verification. While large language models (LLMs) have the potential to automate this task, achieving strong performance requires frontier models such as GPT-5 that are prohibitively expensive to deploy at scale. To efficiently perform biomedical evidence attribution, we present Med-V1, a family of small language models with only three billion parameters. Trained on high-quality synthetic data newly developed in this study, Med-V1 substantially outperforms (+27.0% to +71.3%) its base models on five biomedical benchmarks unified into a verification format. Despite its smaller size, Med-V1 performs comparably to frontier LLMs such as GPT-5, along with high-quality explanations for its predictions. We use Med-V1 to conduct a first-of-its-kind use case study that quantifies hallucinations in LLM-generated answers under different citation instructions. Results show that the format instruction strongly affects citation validity and hallucination, with GPT-5 generating more claims but exhibiting hallucination rates similar to GPT-4o. Additionally, we present a second use case showing that Med-V1 can automatically identify high-stakes evidence misattributions in clinical practice guidelines, revealing potentially negative public health impacts that are otherwise challenging to identify at scale. Overall, Med-V1 provides an efficient and accurate lightweight alternative to frontier LLMs for practical and real-world applications in biomedical evidence attribution and verification tasks. Med-V1 is available at https://github.com/ncbi-nlp/Med-V1.

Autonomous research systems increasingly make the scientific workflow executable: agents can propose ideas, run code, inspect results, and draft papers. But executable workflows do not by themselves produce research judgment. We analyze where current systems lose trial experience: weak evidence becomes prose, pilot signals become broad claims, memory remains textual, and recurring process failures do not change later behavior. We introduce Sibyl-AutoResearch, a self-evolving AutoResearch framework built around Scientific Trial-and-Error Harnesses. A harness lets agents run bounded trials, preserve positive and negative outcomes, and route lessons into later planning, validation, claim scope, scheduling, critique, writing, and harness repair. We formalize this through two auditable conversion units: trial-to-behavior conversion, which links trial signals to later research actions, and trial-to-harness-behavior conversion, which links recurring process failures to system updates. We implement the framework in SIBYL, a file-backed autonomous research system that exposes the state, roles, memory, gates, and artifact traces needed to inspect these conversion paths. A retrospective audit identifies eight high-confidence conversion events, with a median latency of one iteration and a maximum latency of three iterations. A recovered-failure registry further shows how five naturally occurring failure classes, including duplicate results, stale numbers, and unsupported statistics, were blocked, downgraded, or routed into later repair. These traces do not establish a comparative performance claim; they show that the proposed conversion units are recoverable from realistic autonomous-research workspaces. The SIBYL framework and system are available at https://github.com/Sibyl-Research-Team/AutoResearch-SibylSystem.

Vision-language models (VLMs) often underperform on evidence intensive tasks because decisive visual evidence are small, localized, and easy to overlook, leading to failures in evidence readout even when high-level reasoning is intact. Prior inference-time visual interventions can improve grounding without retraining, but they are largely open-loop and lack a mechanism to verify whether highlighted evidence is actually used. We study answer-span prediction entropy as a model-internal feedback signal and show that naive entropy minimization is ambiguous, since low entropy may arise from evidence-grounded confidence or shortcut collapse. To resolve this ambiguity, we introduce low-entropy anchors and an entropy-shaping objective that reduces answer uncertainty while preserving baseline high-confidence tokens. We instantiate this principle in SPOT-E, a plug-and-play test-time method that produces question-conditioned spotlights, optimized per instance via light-weight tuning based on Group Relative Policy Optimization (GRPO). Across all benchmarks and different VLM families, SPOT-E yields consistent gains and improved robustness under visual corruptions. Code is publicly available at: https://github.com/YinBo0927/SPOT-E

Treatment reasoning underpins every therapeutic decision, integrating disease context, comorbidities, medications, contraindications, and evolving biomedical knowledge to select an appropriate therapy. It is inherently iterative: candidates are weighed against many constraints, revised as evidence emerges, and grounded in verifiable sources. Here we introduce ATHENA-R1, an AI agent for treatment reasoning across all FDA approved drugs since 1939, trained by reinforcement learning over a universe of 212 biomedical tools. At each step it identifies missing information, selects and runs relevant tools, and incorporates the evidence. To train it without human-annotated traces, we build a two-level self-learning framework: multi-agent systems construct the tools, tasks, and reasoning trajectories for supervised fine-tuning, then reinforcement learning with scientific feedback rewards reasoning quality (evidence gathering, grounded tool use, logical non-redundancy). Across five benchmarks of 3,168 drug reasoning tasks and 456 patient treatment cases, ATHENA-R1 outperforms language models and tool-use systems, reaching 94.7% accuracy on open-ended drug reasoning and 82.9% on treatment reasoning, 17.8 and 10.7 points above GPT-5. In blinded evaluations by experts from 28 rare disease organizations, it is preferred over reference models on all criteria, and physicians rated it favorably on complex hospitalized cardiovascular and infectious-disease cases. Adverse-event hypotheses it generated, tested in electronic health records from 5.4 million patients, reached adjusted odds ratios of 1.48-1.84, with no elevation among negative controls. Because it requires knowing what evidence to seek before concluding, treatment reasoning has long been hard for AI; we show it can be reframed as a learnable process of iterative evidence gathering that reinforcement learning can train AI to perform.

Large language models (LLMs) exhibit remarkable generative capabilities but often suffer from hallucinations. Retrieval-augmented generation (RAG) offers an effective solution by incorporating external knowledge, but existing methods still face several limitations: additional deployment costs of separate retrievers, redundant input tokens from retrieved text chunks, and the lack of joint optimization of retrieval and generation. To address these issues, we propose RetroLLM, a unified framework that integrates retrieval and generation into a single, cohesive process, enabling LLMs to directly generate fine-grained evidence from the corpus with constrained decoding. Moreover, to mitigate false pruning in the process of constrained evidence generation, we introduce (1) hierarchical FM-Index constraints, which generate corpus-constrained clues to identify a subset of relevant documents before evidence generation, reducing irrelevant decoding space; and (2) a forward-looking constrained decoding strategy, which considers the relevance of future sequences to improve evidence accuracy. Extensive experiments on five open-domain QA datasets demonstrate RetroLLM's superior performance across both in-domain and out-of-domain tasks. The code is available at https://github.com/sunnynexus/RetroLLM.

Standard evaluation protocols reveal a counterintuitive phenomenon: on 7.7% of benchmark problems spanning five datasets, larger language models underperform smaller ones by 28.4 percentage points despite 10-100x more parameters. Through systematic evaluation of 31 models (0.5B-405B parameters) across 1,485 problems, we identify the mechanism as spontaneous scale-dependent verbosity that introduces errors through overelaboration. Causal intervention experiments demonstrate this reflects correctable prompt design rather than fundamental capability limitations. Constraining large models to produce brief responses improves accuracy by 26 percentage points and reduces performance gaps by up to two-thirds. Most critically, brevity constraints completely reverse performance hierarchies on mathematical reasoning and scientific knowledge benchmarks, with large models achieving 7.7-15.9 percentage point advantages over small models -- direct inversions of the original gaps. These reversals prove large models possess superior latent capabilities that universal prompting masks. We validate findings through three independent contamination tests and demonstrate inverse scaling operates continuously across the full parameter spectrum, with dataset-specific optimal scales ranging from 0.5B to 3.0B parameters. Our results establish that maximizing large model performance requires scale-aware prompt engineering rather than universal evaluation protocols, with immediate implications for deployment: prompt adaptation simultaneously improves accuracy and reduces computational costs.

A promising approach for improving reasoning in large language models is to use process reward models (PRMs). PRMs provide feedback at each step of a multi-step reasoning trace, potentially improving credit assignment over outcome reward models (ORMs) that only provide feedback at the final step. However, collecting dense, per-step human labels is not scalable, and training PRMs from automatically-labeled data has thus far led to limited gains. To improve a base policy by running search against a PRM or using it as dense rewards for reinforcement learning (RL), we ask: "How should we design process rewards?". Our key insight is that, to be effective, the process reward for a step should measure progress: a change in the likelihood of producing a correct response in the future, before and after taking the step, corresponding to the notion of step-level advantages in RL. Crucially, this progress should be measured under a prover policy distinct from the base policy. We theoretically characterize the set of good provers and our results show that optimizing process rewards from such provers improves exploration during test-time search and online RL. In fact, our characterization shows that weak prover policies can substantially improve a stronger base policy, which we also observe empirically. We validate our claims by training process advantage verifiers (PAVs) to predict progress under such provers, and show that compared to ORMs, test-time search against PAVs is >8% more accurate, and 1.5-5times more compute-efficient. Online RL with dense rewards from PAVs enables one of the first results with 5-6times gain in sample efficiency, and >6% gain in accuracy, over ORMs.

Synthesizing clinical evidence largely relies on systematic reviews of clinical trials and retrospective analyses from medical literature. However, the rapid expansion of publications presents challenges in efficiently identifying, summarizing, and updating clinical evidence. Here, we introduce TrialMind, a generative artificial intelligence (AI) pipeline for facilitating human-AI collaboration in three crucial tasks for evidence synthesis: study search, screening, and data extraction. To assess its performance, we chose published systematic reviews to build the benchmark dataset, named TrialReviewBench, which contains 100 systematic reviews and the associated 2,220 clinical studies. Our results show that TrialMind excels across all three tasks. In study search, it generates diverse and comprehensive search queries to achieve high recall rates (Ours 0.711-0.834 v.s. Human baseline 0.138-0.232). For study screening, TrialMind surpasses traditional embedding-based methods by 30% to 160%. In data extraction, it outperforms a GPT-4 baseline by 29.6% to 61.5%. We further conducted user studies to confirm its practical utility. Compared to manual efforts, human-AI collaboration using TrialMind yielded a 71.4% recall lift and 44.2% time savings in study screening and a 23.5% accuracy lift and 63.4% time savings in data extraction. Additionally, when comparing synthesized clinical evidence presented in forest plots, medical experts favored TrialMind's outputs over GPT-4's outputs in 62.5% to 100% of cases. These findings show the promise of LLM-based approaches like TrialMind to accelerate clinical evidence synthesis via streamlining study search, screening, and data extraction from medical literature, with exceptional performance improvement when working with human experts.

The increasing adoption of large language models (LLMs) has been accompanied by growing concerns regarding their reliability and trustworthiness. As a result, a growing body of research focuses on evidence-based text generation with LLMs, aiming to link model outputs to supporting evidence to ensure traceability and verifiability. However, the field is fragmented due to inconsistent terminology, isolated evaluation practices, and a lack of unified benchmarks. To bridge this gap, we systematically analyze 134 papers, introduce a unified taxonomy of evidence-based text generation with LLMs, and investigate 300 evaluation metrics across seven key dimensions. Thereby, we focus on approaches that use citations, attribution, or quotations for evidence-based text generation. Building on this, we examine the distinctive characteristics and representative methods in the field. Finally, we highlight open challenges and outline promising directions for future work.