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Lyndsi Houskeeper's new CD is music for youth.
The LDS Church's theme for Young Men and Young Women this year, “Stand Ye in Holy Places” (see Doctrine and Covenants 87:8), was the inspiration for Lyndsi Houskeeper's newest album, “Stand in Holy Places.” Houskeeper, a singer-songwriter, uses her personal experiences to write songs that are touching and elevating. Complete with 16 tracks, this CD is targeted specifically to youths, though its messages are universal and meant to give hope to all listeners.
The title track, "What Will I Stand For," calls on the youths of The Church of Jesus Christ of Latter-day Saints to find the courage to make the right choices while they are young. The question-and-promise format of this song pulls into the lyrics a version of a familiar theme: “Choose the right.” Houskeeper has included the sheet music for “What Will I Stand For” on her personal blog at lyndsihmusic.blogspot.com.
"Shoes" brings to mind the trials everyone faces, and urges listeners to have a thankful heart despite those challenges. The song "Because I Love Him" highlights Houskeeper's strong vocals, and infuses the listener with a simple message. Her rendition of “How Great Thou Art” shows the depth of feeling she brings into each word of the song.
As a bonus, Houskeeper has included seven tracks as both voice and instrumental. The instrumental versions may be used freely to accompany youths' voices in firesides, New Beginnings, Evenings of Excellence and other activities.
Houskeeper, a motivational speaker and mother of three, has grown a loyal audience over the past 10 years. Her desire in writing and sharing music is to uplift others with her gift. Her latest album does just that, and leaves the listener with a resolve to make better choices, seek for hope, and capture light while standing in holy places.
Amy Jo Wilde is a writer living in Brigham City. She blogs at www.amyjowilde.com and her email is [email protected]. Follow her on Twitter at wildeatmosphere.


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Can your specialists achieve the mission objective at all costs? Get your Kill Team to battle and find out!
Join us for a Kill Team League running until September 20th. Bring a 100 pt Matched Play Kill Team and battle to be top dog!

industry_corpus2: Gaming


text:
adj. done by patching; "The contractor did a quick patch-up job to fix the wall."
adj. mend by putting a patch on; "patch a hole"

industry_corpus2: Others


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To determine the admission arrangements for community and voluntary controlled schools for the school year 2017/18.
This is deemed to be a Key Decision and the provisions of Standing Order No. 25 have been complied with.
(iii) that the admission numbers and criteria for admission set out at (a) and (b), together with the other information included on the Authority’s website and in its admissions booklets, shall constitute the admission arrangements for 2017/18.

industry_corpus2: Subject Education


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DENVER – Annabel Bowlen, the wife of Denver Broncos owner Pat Bowlen, announced Wednesday that she, too, has been diagnosed with Alzheimer’s disease.
The announcement comes just four years after Pat Bowlen announced his own battle with the disease .
"I recently learned that I've joined my husband Pat and the millions of others who have been diagnosed with Alzheimer's disease.
Since Pat's diagnosis, I have gained a vivid understanding of this disease’s progression and its effect on those living with it as well as their families. My family and I have been — and will remain — dedicated supporters of Alzheimer's awareness, treatment and research funding.
I decided to make my diagnosis public right away in the hope that it continues to raise awareness for those battling Alzheimer's and their loved ones. With June also being Alzheimer's & Brain Awareness Month, the timing was right for me to share this personal update with everyone.
I feel that it is important for people to know that those in my situation do not need to completely withdraw from their daily activities. Based on my own experience with Pat, there will still be many joyous and rewarding moments for me as well as my family and friends.
I intend to proceed in life with the same strength, courage and endurance that Pat has shown in his battle with this disease. Like Pat, I know there will be good days and bad days ahead. I'm grateful to have the support of my family and especially my children — Patrick, Johnny, Brittany, Annabel and Christianna.
It's my hope to remain involved in various Alzheimer's events as my health allows. And of course, I'll be cheering on our Broncos.
Most importantly, thank you to all of our incredible fans for the compassion and support you've given to me, Pat and our entire family."
Denver Broncos President and CEO Joe Ellis said the entire team stands behind the Bowlens.
The team said Bowlen’s announcement will not affect the team’s operations or Pat Bowlen’s plan for succession.
Since 2014, the Bowlens and the Broncos have raised more than $500,000 for the Alzheimer’s Association Colorado Chapter, the team said.

industry_corpus2: Health & Medicine


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Bulk Bag Depot’s Duffle Top / Flat Bottom bulk bags are offered in a variety of sizes and configurations. Specifications for our in-stock bulk bags are outlined below. For custom sizes and design requests, please contact our product specialists at (800) 645-3183.
Custom Duffle Top / Flat Bottom sizes are also available. Please contact us to request a quote.

industry_corpus2: Manufacturing


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This past weekend police in Amesbury, Massachusetts executed a search warrant at a home in a quiet residential neighborhood. At home during the raid, and charged with various drug crimes were Christopher Doty and Kristen Cataldo, both in their mid twenties. The search warrant was issued after police had obtained information regarding drug activity in the home. The information apparently came from informants and possibly a sustained surveillance or controlled drug buys. The defendants have been charged with an assortment of crimes including possession with the intent to distribute class A and class B drugs, assault and battery on a police officer, child endangerment and possession of a dangerous weapon.
According to the article in the Newburyport News the drugs were found in containers in an undisclosed area of the home. The quantity of drugs alleged exceeds what one would expect from a user, thus suggesting an intent to distribute. The major question here is who is responsible for what. Simply executing a search warrant and finding drugs doesn’t always satisfy the district attorney’s burden of proving felony drug cases. Nor does it show who, Doty or Cataldo, was responsible for what. As I have often discussed, presence alone will not get the prosecutor a conviction. Police officer observations made during surveillance activities is often flawed as well. Unless the officers participated in a controlled buy it is difficult to establish criminal activity based on simple observations.
In cases like this cops often report the following to support their suspicions: seeing what appeared to be exchanges at the door of the home, unusually high foot traffic by the house, large numbers of visitors appearing at the home for a short period of time, people leaving the property carrying an object that they didn’t have when they entered the property. All of these observations are consistent with non-criminal behavior was well. Moreover, most of this “activity” is not video recorded or photographed thereby lending more doubt to the allegations. Finally, there is always the attack on the validity of the search warrant itself that can result in the dismissal of a drug case.
The article I read about this case states that “[t]he warrant was served without incident”. It further stated that an officer sustained a minor injury when attempting to gain entry to the home. I am not sure where the assault and battery on a police officer comes from but clearly this article suggests that this crime is not real in this case.
What About the Child Endangerment Charges?
Massachusetts General Laws Chapter 265 Section 13L states that anyone engaging in wanton or reckless conduct that presents a risk of serious bodily injury to a child is guilty of a crime. This law is extremely broad. Judges are afraid to dismiss these charges in most cases. Prosecutors are likely to use this charge as leverage to either get one party to testify against the other or to force a resolution of the case. The collateral consequences of a conviction can be devastating to the accused and his or her family.
What is interesting about this case is that there are no minimum mandatory sentences associated with any of the charges. Resolving this case short of trial is foreseeable particularly if Doty and Cataldo have no criminal records or minimal criminal records. There are defenses to all cases. Our office has been defending drug cases in Essex County Massachusetts for nearly thirty years. Call us now at 617-263-6800 or send us an email. Lets get started with defending your case now.

industry_corpus2: Law & Justice


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“They don’t know we live in Mara Salvatrucha territory,” she said.
El Salvador’s capital _ and indeed nearly the entire country _ is a checkerboard in which gang territories circumscribe the movement of those in the lower economic rungs of society, and especially young men. When a family lives in an area dominated by one gang, it avoids going to an area controlled by a rival gang.
“The control the gangs hold over their territories has never been so complete. It is without precedent,” said Carlos E. Ponce, a criminologist and former adviser to the National Civilian Police.
As the gangs deepen connections with regional organized-crime groups involved in drug, weapons and human trafficking, they present a direct challenge to state control over the tiny Central American nation, Ponce said.
The chaos also provides an incentive for Salvadorans to try to flee north for the safety of the United States. Experts trying to explain the huge increase in children and teens who’ve arrived in the United States say anecdotal evidence points at least in part to the hold that criminal gangs have in El Salvador, Honduras and Guatemala.
As insecurity extends across El Salvador, gang bosses reach for younger and younger kids to fill their ranks.
In Ilopango, a poor sprawling district southeast of the capital, the local government has set up programs to offer training to young people in driving and speaking English. But district authorities have found they have to duplicate some programs, one for areas controlled by the Mara Salvatrucha and another for Barrio 18 areas.
Hernandez said the two gangs had different clothing and hairstyles, even different vocabularies.
“It sounds ridiculous but there are things that Mara Salvatrucha gang members won’t say. They never say eight or 18,” he said, for fear of referring to the rival gang.
While flight to the United States might be one way people are trying to escape the violence, there’s an ironic symmetry: El Salvador’s gang problem has its genesis in the United States, from the time of the country’s civil war, which also sent tens of thousands of Salvadorans fleeing to the United States.
For young people, that war _ which wracked El Salvador from 1980 to 1992 and left at least 75,000 civilians dead _ is ancient history. But by the time peace accords were signed, the gangs were on the rise, formed by gang members who’d been deported from Los Angeles.
Salvadoran leaders have tried different tactics to rein in the gangs, beginning with a 2003 program, known as “Strong Hand” and followed by “Super Strong Hand” years later, that swept thousands of gang members into prisons.
“The ‘Strong Hand’ program only attacked the gang members who were on the street. It filled the jails. But it didn’t touch the leaders,” Ponce said.
In 2012, the government _ with the help of the Organization of American States _ brokered a truce between leaders of the two gangs that edged the nation’s homicide rate down from 12 killings a day to around five. But that truce fell apart earlier this year and homicides are back up. One recent weekend tallied 31 violent deaths.
Now the citizenry widely ridicules the truce.
“Most people say it didn’t do any good. They feel it was a nonaggression pact between leaders of the two gangs but that ordinary civilians still paid the price,” said Monica Pacheco, the coordinator of a Roman Catholic human-rights observatory based in San Salvador’s working-class Mejicanos district.
One former Mara Salvatrucha member, Marvin Gonzalez, who spent 10 years in prison for murder and has been free since 2012, said reconciliation between rival gangs was a monumental task.
Even if gang violence were to diminish, for people such as Mirna Villalta the suffering will go on.
The police and prosecutors got involved anyway, and several gang members are in prison for involvement in the murder.
Villalta has sons aged 10 and 13, and she fears that the gang will force them to join. One day, her 10-year-old disappeared from behind her food stall. He was gone for nearly half a day. Witnesses said a woman led him to a taxi. The boy stepped out of a taxi near her home late that night.
She and social workers suspect that gang members took him to frighten him into joining.
Villalta is now working with a lawyer and seeking humanitarian asylum in Sweden. It’s been granted, and all she needs is the airfare, said lawyer Karla Salas.


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Renoir cinemas started the adventure of showing art-house films in original version with subtitles in 1986. In Spain this is not at all common as films are normally dubbed in most of the cinemas and therefore we are now a reference for film lovers in Madrid and Barcelona.
We have 3 cinemas in Madrid (Renoir Plaza España, Renoir Retiro and Cines Princesa) and 1 cinema in Barcelona (Renoir Floridablanca) where we show a selection of new release films in original language that are likely to appeal to a more art house audience.
In the selection of films that we show we give a great importance to European and Spanish films.
We are especially proud of the summer program which is composed of the best films of the year at a low price. It has been 5 years now from its implementation and it is always a great success with full house in many screenings.
For Renoir’s 30th anniversary this year we organise a short story contest related to cinema and we will show some of the best films of cinema history in the next months.
Find out who is Renoir’s Ambassador here.
Posted in 28 Times Cinema 2016, Cinema Portraits and tagged @28TimesCinema, @cinesrenoir, @EuropaCinemas, @LUX Cinema Prize, @Spain, @VeniceDays. Bookmark the permalink.

industry_corpus2: Film & Entertainment


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1. Sawatzky, B., DiGiovine, C., Berner, T., et al: ‘The need for updated clinical practice guidelines for preservation of upper extremities in manual wheelchair users, a position paper’, Am. J. Phys. Med. Rehabil., 2015, 94, (4), pp. 313–324 (doi: 10.1097/PHM.0000000000000203).
2. Cowan, R.E., Boninger, M.L., Sawatzky, B.J., et al: ‘Preliminary outcomes of the SmartWheel Users’ Group database: a proposed framework for clinicians to objectively evaluate manual wheelchair propulsion’, Arch. Phys. Med. Rehabil., 2008, 89, (2), pp. 260–268 (doi: 10.1016/j.apmr.2007.08.141).
3. DeGroot, K.K., Hollingsworth, H.H., Morgan, K.A., et al: ‘The influence of verbal training and visual feedback on manual wheelchair propulsion’, Disabil. Rehabil. Assist. Technol., 2009, 4, (2), pp. 86–94 (doi: 10.1080/17483100802613685).
4. Rice, I.M., Pohlig, R.T., Gallagher, J.D., et al: ‘Handrim wheelchair propulsion training effect on overground propulsion using biomechanical real-time visual feedback’, Arch. Phys. Med. Rehabil., 2013, 94, (2), pp. 256–263 (doi: 10.1016/j.apmr.2012.09.014).
5. Richter, W.M., Kwarciak, A.M., Guo, L., et al: ‘Effects of single-variable biofeedback on wheelchair Handrim biomechanics’, Arch. Phys. Med. Rehabil., 2011, 92, (4), pp. 572–577 (doi: 10.1016/j.apmr.2010.11.001).
6. de Groot, S., Veeger, H.E.J., Hollander, A.P., et al: ‘Consequence of feedback-based learning of an effective hand rim wheelchair force production on mechanical efficiency’, Clin. Biomech., 2002, 17, (3), pp. 219–226 (doi: 10.1016/S0268-0033(02)00005-0).
7. Kotajarvi, B.R., Basford, J.R., An, K.N., et al: ‘The effect of visual biofeedback on the propulsion effectiveness of experienced wheelchair users’, Arch. Phys. Med. Rehabil., 2006, 87, (4), pp. 510–515 (doi: 10.1016/j.apmr.2005.12.033).
8. Sigrist, R., Rauter, G., Riener, R., et al: ‘Augmented visual, auditory, haptic, and multimodal feedback in motor learning: A review’, Psychon. Bull. Rev., 2013, 20, (1), pp. 21–53 (doi: 10.3758/s13423-012-0333-8).
9. Meardon, S.A., Derrick, T.R.: ‘Effect of step width manipulation on tibial stress during running’, J. Biomech., 2014, 47, (11), pp. 2738–2744 (doi: 10.1016/j.jbiomech.2014.04.047).
10. Helmer, R.J.N., Farrow, D., Ball, K., et al: ‘A pilot evaluation of an electronic textile for lower limb monitoring and interactive biofeedback’. Fifth Asia-Pacific Congress on Sports Technology, Melborne, Australia, August 2011, vol. 13, pp. 513–518.
11. Mason, B., van der Woude, L., Lenton, J.P., et al: ‘The effect of wheel size on mobility performance in wheelchair athletes’, IEE J. Sports Med., 2012, 33, (10), pp. 807–812.
12. Holloway, C.S., Symonds, A., Suzuki, T., et al: ‘Linking wheelchair kinetics to glenohumeral joint demand during everyday accessibility activities’. Conf. Proc. IEEE Engineering in Medicine and Biology Society, Milan, Italy, August 2015, pp. 2478–2481.
14. Boninger, M.L., Dicianno, B.E., Cooper, R.A., et al: ‘Shoulder magnetic resonance imaging abnormalities, wheelchair propulsion, and gender’, Arch. Phys. Med. Rehabil., 2003, 84, (11), pp. 1615–1620 (doi: 10.1053/S0003-9993(03)00282-X).
15. Rankin, J.W., Kwarciak, A.M., Richter, W.M., et al: ‘The influence of wheelchair propulsion technique on upper extremity muscle demand: a simulation study’, Clin. Biomech., 2012, 27, (9), pp. 879–886 (doi: 10.1016/j.clinbiomech.2012.07.002).
16. Boninger, M.L., Waters, R.L., Chase, T., et al: ‘Preservation of upper limb function following spinal cord injury: a clinical practice guideline for health-care professionals’, J. Spinal Cord Med., 2005, 28, (5), pp. 433–470.
17. Veeger, H.E.J., Rozendaal, L.A., van der Helm, F.C.T.: ‘Load on the shoulder in low intensity wheelchair propulsion’, Clin. Biomech., 2002, 17, (3), pp. 211–218 (doi: 10.1016/S0268-0033(02)00008-6).
18. Westerhoff, P., Graichen, F., Bender, A., et al: ‘In vivo measurement of shoulder joint loads during activities of daily living’, J. Biomech., 2009, 42, (12), pp. 1840–1849 (doi: 10.1016/j.jbiomech.2009.05.035).
19. Hoxie, R.E., Rubenstein, L.Z.: ‘Are older pedestrians allowed enough time to cross intersections safely’, J. Am. Geriatr. Soc., 1994, 42, (3), pp. 241–244 (doi: 10.1111/j.1532-5415.1994.tb01745.x).
20. Hwang, S., Kim, S., Son, J., et al: ‘Upper limb joint motion of two different user groups during manual wheelchair propulsion’, J. Korean Phys. Soc., 2013, 62, (4), pp. 648–656 (doi: 10.3938/jkps.62.648).
21. Newsam, C.J., Mulroy, S.J., Gronley, J.K., et al: ‘Temporal-spatial characteristics of wheelchair propulsion – effects of level of spinal cord injury, terrain, and propulsion rate’, Am. J. Phys. Med. Rehabil., 1996, 75, (4), pp. 292–299 (doi: 10.1097/00002060-199607000-00010).
22. Sonenblum, S.E., Sprigle, S., Lopez, R.A.: ‘Manual wheelchair use: bouts of mobility in everyday life’, Rehabil. Res. Pract., 2012, 2012, p. 753165.
23. Hurd, W.J., Morrow, M.M.B., Kaufman, K.R., et al: ‘Wheelchair propulsion demands during outdoor community ambulation’, J. Electromyogr. Kinesiol., 2009, 19, (5), pp. 942–947 (doi: 10.1016/j.jelekin.2008.05.001).
24. Wheeler, J.W., Shull, P.B., Besier, T.F.: ‘Real-time knee adduction moment feedback for gait retraining through visual and tactile displays’, J. Biomech. Eng.-T ASME, 2011, 133, (4), p. 041007 (doi: 10.1115/1.4003621).


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Turn your phone into light saber ! Touch the screen or shake your phone to play. You can change the colors. The background is transparent to be more realistic. The lights sparkles like a star for each contact.
3.Open Android Emulator for PC Windows import the Light Saber APK file from your PC Into Android Emulator to install it.
4.Install Light Saber APK APPS for PC Windows.Now you can play Light Saber APK on PC.

industry_corpus2: Computing & Telecommunications


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Maybe you've been there for a conference. Or maybe you've been there for one of its many live musical events.
But the next time you visit The Old Stone in downtown Bend, chances are it will be under new ownership. Owner Mardy Hickerson announced today that The Old Stone is up for sale, and no events will scheduled after Oct. 31 (that's yesterday, in case you were confused).
Hickerson said in a statement Nov. 1: "It has been a true pleasure, to have collaborated with so many artists, families and community groups that created beautiful, impactful and fun events. The Old Stone has a bright future in a growing town full of potential."
The property, built in 1913 as a church, and later used as a creative space and performing arts center, is available through Fratzke Commercial.

industry_corpus2: Real Estate & Construction


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Home Sublease versus Co-Working Spaces. Which is the right one for you?
Hardly a day goes by without me seeing yet another article in the real estate news concerning co-working or managed office spaces. Each time I come across an article touting the benefits, I wonder why more tenants don’t take advantage or at least explore some other good alternatives that costs a fraction of the price and offer the same or more benefits, namely subleases that can either be shared with another company or private.
Just like co-working spaces or executive office centers, a shared sublease can offer all or most of the same benefits: flexible lease term, low security deposit requirement, furnished and wired space, the ability to expand or contract, shared meeting spaces, and a stocked pantry. The difference is that with a shared sublease you get full identity with your companies name on the door along with knowing the people you will be sharing the space with. With Co-Working or executive center space you get virtually no identity and you don’t know from one day to the next, who will be your neighbor. In addition to identity and having roommates you know, there are other advantages, including getting a bigger and better space, no additional charges for services and unlimited use of common areas.
The other option that is similar but for larger space requirements, are managed sublet spaces that come with services. There are companies now that take the obligation of a long term lease on a space at market rates and then turn around and sublease the same space back for about double what they rented it for. They justify the higher rent by offering a shorter term lease (typically minimum 2 years) and providing the convenience of a furnished space, which includes a stocked pantry and broadband services included in the rent. Hardly worth it when you consider the difference in cost. Sublease spaces typically comprise the tail end of a lease, so they usually have a shorter term anyway, and trade below, not above, market, so you actually save money, not spend more. In addition, they offer most of the same benefits, including a furnished space that is fully wired, so all you end up paying extra for is the broadband service and stocking the refrigerator.
I have built my career in real estate representing tenants and looking for the best value in the market for my clients. I would highly recommend that a tenant in the market looking for short term, flexible space lease, consider either a shared or private sublet space before committing to one of the more expensive managed space options.
Whichever direction you ultimately go, it always helps to have an experienced real estate professional at your side to evaluate all your options and help you make an informed decision that is right for you. With our experience and knowledge, and at no costs to you, we can evaluate all the options including the managed spaces and sublets spaces to help you decide which would work best for your business.


text: This sports bra is ideal for the full-figured woman who is looking for a medium to high impact option that still offers a natural shape. It will flatter your curves both inside and outside of the gym, since its seamless non-stretch cups provide bounce control and look smooth under your clothes. Experience the comfort you've been missing!

industry_corpus2: Sports


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What do Apple, Barclays, Infosys and McDonald’s have in common? They are all businesses that operate internationally; with clients and employees spread across the world. Operating across the borders is not a strategy exclusive to just the large players. Even small businesses are waking up to the potential benefits of trading across several different countries. Political developments like creation and implementation of trade deals and free trade zones are fuelling businesses to look overseas to sell, source resources and services and meagre or cooperate with foreign businesses.
By studying international business management, you will be prepared for a career with multinational companies, government and organisations with a global focus. You will learn the fundamentals of business and be able to specialise in marketing, management or accounting, depending on the institution’s offering.
International business management professionals are needed by virtually every company in every sector, including IT and tech, retail and hospitality, banks and pharmaceutical companies.
Some of the roles graduates take up are International Business Development Officer, International Trader, International Sales Manager, Management Analyst/Consultant and Finance Controller.
Salaries vary depending on qualifications, job role, location and experience. As a guide, international business management professionals earn around an average of $76,000 a year (41 lakhs INR).

industry_corpus2: Finance & Economics


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This group is for anyone who paints or loves the magic of the watercolor media. Landscapes, seascapes, florals, still life, nudes...you name it, modern, realism, abstracts. Come in share your ideas and browse beautiful art.
Birth of Earth#2. "As far as the eye of God could see"
The Birth of Earth #1.


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What's up? After I moved to the States, it took me years to learn how to answer that friendly question. Colleagues would glare at me as I stood stammering, blushing, or simply walked away in defeat. "Fine thank you" became my muttered reply. I figured I was being asked, "How are you?" Or, "How are things today?" Turns out, like many sayings, it can mean whatever you want it to mean. I settle for, "What's been going on since we last spoke?" The British just say, succintly, "How are you?" Or, as my grandmother said, "'ubby?" Short for "How be (you doing today)?"
So, what's up? Can't say I've been doing much cooking of late, but I've sure been curious! The busyness of being in business has kept me busy, busier than my perennially busy Mother-in-law! Busier than the sweatshop apiary that keeps me in local honey! That's a JOKE Rick - I know Buzzter and the crew get meal breaks.
I'm busy planning our move to our, new 'undisclosed location.' I'm busy working with the fine guys at http://www.finelinewebsites.com/ getting our web site redesigned and relaunched. I'm busy being our Produce Manager, Store Manager, HR, IT, and Marketing departments, and well, busy 'Knowing Yum!' I'm having fun right now learning all about grape varietals with the objective of understanding food pairings better and reducing the crap shoot that buying wine often is. I'm finding out all sorts of (often confusing) information. Did you know the French were the first to sequence the genome of a fruit? It was the Pinot Noir grape, sequenced in August, 2007. C'est vrai! Je l'ai lu sur l'Internet! It's true. I read it on the Internet!
Earth shattering news. I cleaned out the home fridge this week. I cant stop looking at it. I'm marvelling at how the inside of a fridge can go from looking like it got rolled downhill to a model home in one afternoon. It made me think. E-mail me photos of the inside of your fridge goodforu@comcast.net For any that, a) Make me laugh or b) Impress me AND in either case get chosen for publication in Good For You Market's E-News, "The Grapevine," I will reward you with a $5 Green Buck coin good for redemption in store at Good For You Market.
Oh, to cue, the store calls, busy is a good thing. Good For You!

industry_corpus2: Agriculture & Fisheries


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Wheatley School Educational Technology staff is ready to help teachers and students integrate technology into their curricula and projects. The use of technology by the teachers and students has become an essential component of every day instructional practices. Wheatley School strives to provide teachers and students with the appropriate technology opportunities to support their teaching and learning. All students have access to the IMC Student Production Room equipped with computers, scanner and printers throughout the day. Every classroom is equipped with a computer, DVD player, ceiling mounted projector, VCR and a document camera or overhead projector. Many of our classrooms have Smart board’s, an interactive whiteboard.
Wheatley School courses are offered, with honors or accelerated programs in mathematics, science, English and foreign languages. Sixteen college-level courses in English, Spanish, French, American & European History, government, economics, art, calculus, biology, chemistry, physics, statistics, and computer science challenge the talented student body. Wheatley supports a wide variety of co-curricular activities for students. The school publishes a monthly newspaper, an annual poetry and art magazine, and a yearbook. Students participate in scholastic competitions through mock trial teams, computer and math teams, and the Brainstormers team.
Did you graduate from Wheatley School?
Show your Wheatley school spirit with our graduation widget!


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Arguing that "reason, intelligence, logic, knowledge are not synomous. . .", Howard Gardner (1983) proposed a new view of intelligence that is rapidly being incorporated in school curricula. In his Theory of Multiple Intelligences, Gardner expanded the concept of intelligence to also include such areas as music, spacial relations, and interpersonal knowledge in addition to mathematical and linguistic ability.
This digest discusses the origins of Gardner's Theory of Multiple Intelligences, his definition of intelligence, the incorporation of the Theory of Multiple Intelligences into the classroom, and its role in alternative assessment practices.
Logical-Mathematical Intelligence--consists of the ability to detect patterns, reason deductively and think logically. This intelligence is most often associated with scientific and mathematical thinking.
Linguistic Intelligence-- involves having a mastery of language. This intelligence includes the ability to effectively manipulate language to express oneself rhetorically or poetically. It also allows one to use language as a means to remember information.
Spatial Intelligence-- gives one the ability to manipulate and create mental images in order to solve problems. This intelligence is not limited to visual domains-- Gardner notes that spatial intelligence is also formed in blind children.
Bodily-Kinesthetic Intelligence-- is the ability to use one's mental abilities to coordinate one's own bodily movements. This intelligence challenges the popular belief that mental and physical activity are unrelated.
The Personal Intelligences-- includes interpersonal intelligence -- the ability to understand and discern the feelings and intentions of others-- and intrapersonal intelligence --the ability to understand one's own feelings and motivations. These two intelligences are separate from each other. Nevertheless, because of their close association in most cultures, they are often linked together.
Although the intelligences are anatomically separated from each other, Gardner claims that the seven intelligences very rarely operate independently. Rather, the intelligences are used concurrently and typically complement each other as individuals develop skills or solve problems. For example, a dancer can excel in his art only if he has 1) strong musical intelligence to understand the rhythm and variations of the music, 2) interpersonal intelligence to understand how he can inspire or emotionally move his audience through his movements, as well as 3) bodily-kinesthetic intelligence to provide him with the agility and coordination to complete the movements successfully.
Gardner argues that there is both a biological and cultural basis for the multiple intelligences. Neurobiological research indicates that learning is an outcome of the modifications in the synaptic connections between cells. Primary elements of different types of learning are found in particular areas of the brain where corresponding transformations have occurred. Thus, various types of learning results in synaptic connections in different areas of the brain. For example, injury to the Broca's area of the brain will result in the loss of one's ability to verbally communicate using proper syntax. Nevertheless, this injury will not remove the patient's understanding of correct grammar and word usage.
In addition to biology, Gardner (1983) argues that culture also plays a large role in the development of the intelligences. All societies value different types of intelligences. The cultural value placed upon the ability to perform certain tasks provides the motivation to become skilled in those areas. Thus, while particular intelligences might be highly evolved in many people of one culture, those same intelligences might not be as developed in the individuals of another.
Accepting Gardner's Theory of Multiple Intelligences has several implications for teachers in terms of classroom instruction. The theory states that all seven intelligences are needed to productively function in society. Teachers, therefore, should think of all intelligences as equally important. This is in great contrast to traditional education systems which typically place a strong emphasis on the development and use of verbal and mathematical intelligences. Thus, the Theory of Multiple Intelligences implies that educators should recognize and teach to a broader range of talents and skills.
Another implication is that teachers should structure the presentation of material in a style which engages most or all of the intelligences. For example, when teaching about the revolutionary war, a teacher can show students battle maps, play revolutionary war songs, organize a role play of the signing of the Declaration of Independence, and have the students read a novel about life during that period. This kind of presentation not only excites students about learning, but it also allows a teacher to reinforce the same material in a variety of ways. By activating a wide assortment of intelligences, teaching in this manner can facilitate a deeper understanding of the subject material.
Everyone is born possessing the seven intelligences. Nevertheless, all students will come into the classroom with different sets of developed intelligences. This means that each child will have his own unique set of intellectual strengths and weaknesses. These sets determine how easy (or difficult) it is for a student to learn information when it is presented in a particular manner. This is commonly referred to as a learning style. Many learning styles can be found within one classroom. Therefore, it is impossible, as well as impractical, for a teacher to accommodate every lesson to all of the learning styles found within the classroom. Nevertheless the teacher can show students how to use their more developed intelligences to assist in the understanding of a subject which normally employs their weaker intelligences (Lazear, 1992). For example, the teacher can suggest that an especially musically intelligent child learn about the revolutionary war by making up a song about what happened.
As the education system has stressed the importance of developing mathematical and linguistic intelligences, it often bases student success only on the measured skills in those two intelligences. Supporters of Gardner's Theory of Multiple Intelligences believe that this emphasis is unfair. Children whose musical intelligences are highly developed, for example, may be overlooked for gifted programs or may be placed in a special education class because they do not have the required math or language scores. Teachers must seek to assess their students' learning in ways which will give an accurate overview of the their strengths and weaknesses.
As children do not learn in the same way, they cannot be assessed in a uniform fashion. Therefore, it is important that a teacher create an "intelligence profiles" for each student. Knowing how each student learns will allow the teacher to properly assess the child's progress (Lazear, 1992). This individualized evaluation practice will allow a teacher to make more informed decisions on what to teach and how to present information.
Traditional tests (e.g. multiple choice, short answer, essay. . .) require students to show their knowledge in a predetermined manner. Supporters of Gardner's theory claim that a better approach to assessment is to allow students to explain the material in their own ways using the different intelligences. Preferred assessment methods include student portfolios, independent projects, student journals, and assigning creative tasks. An excellent source for a more in-depth discussion on these different evaluation practices is Lazear (1992).
Schools have often sought to help students develop a sense of accomplishment and self-confidence. Gardner's Theory of Multiple Intelligences provides a theoretical foundation for recognizing the different abilities and talents of students. This theory acknowledges that while all students may not be verbally or mathematically gifted, children may have an expertise in other areas, such as music, spatial relations, or interpersonal knowledge. Approaching and assessing learning in this manner allows a wider range of students to successfully participate in classroom learning.
Blythe, T., & Gardner H. (1990). A school for all intelligences.Educational Leadership. 47(7), 33-37.
Gardner, H. (1983). Frames of Mind. New York: Basic Book	Inc.
Gardner, H. (1991) The unschooled mind: how children think and how schools should teach.New York: Basic Books Inc.
Gardner, H., & Hatch, T. (1989). Multiple intelligences go to school: Educational implications of the theory of multiple intelligences. Educational Researcher, 18(8), 4-9.
This publication was prepared with funding from the Office of Educational Research and Improvement, U.S. Department of Education, under contract RR93002002. The opinions expressed in this report do not necessarily reflect the positions or policies of OERI or the U.S. Department of Education. Permission is granted to copy and distribute this ERIC/AE Digest.


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“Our main goal is to help students build independent life skills,” said Aerius Franklin, a DAC independent living advocate.
The Disability Action Center (DAC) Northwest in Moscow is offering high school and college students with disabilities in the Moscow and Pullman area the chance to explore career opportunities and potentially get a job with local businesses Thursday.
Aerius Franklin, an independent living advocate at the DAC, started the annual Career Mentoring Day in 2012. He said partnering with local business owners to help disabled students land their dream job or learn more about what they want to do is a very rewarding experience.
He said career opportunities vary based on each individual and their interests after college.
He said before students can jump into a job, they have to spend part of the day going through the hiring process.
Students must fill out an application and go through an interview to better prepare them to enter the work force on their own, he said. This year there are over 20 students exploring numerous fields such as baking, mechanical engineering, welding and Habitat for Humanity.
The career day is open to anyone ages 16 to 24, and the DAC wants attendees to have fun, Franklin said. However, they also have to be performing well in school and show a professional attitude.
Franklin said he sees this program continuing for many years to come. The event will take place from 8:30 a.m. to 2:30 p.m. Thursday at the Fairfield Inn in Moscow.
Isaac is a freshman sports management major with a minor in communication. He is from Tacoma, Washington.


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Today, Mississippians cast their ballots in a runoff election that will determine whether incumbent Sen. Cindy Hyde-Smith (R) will hang on to her seat — or if Democratic challenger Mike Espy will prevail and become the state’s first black senator in Mississippi.
If it were up to Hyde-Smith, she would bolster her chances by making it it more difficult for some voters in her state to cast their ballots — in particular those likely to oppose her.
Hyde-Smith is not the only Republican caught revealing the real motivation behind GOP efforts to craft new election laws and redraw congressional districts. Rather than tout voter identification laws as a measure to protect against fraud or partisan gerrymandering as inevitable, some Republicans, in unguarded moments, now are telling the truth: voter suppression helps them win.
After the video of Hyde-Smith circulated online, her team was quick to first dismiss the comment as a joke, only later to claim the video had been selectively edited.
Other Republicans have also let loose — although they usually try to keep their views private. A lawsuit laid bare Michigan’s incumbent Republicans’ concerted efforts to manipulate the 2011 redistricting process to their advantage. Emails filed in the lawsuit show that sitting lawmakers at both state and congressional levels consulted Republican donors.
Their language indicates just how invested they were in using the maps to maintain control. When proposed district lines allowed for too much leeway, lawmakers said they were “beyond pissed” or “just hated” the process. Consultants reacted accordingly, re-configuring lines to better suit their clients.
The League of Women Voters filed a lawsuit last month that claims the map is both unconstitutional and must be redrawn.
But despite backdoor dealings, Michiganders voted to adopt an independent redistricting commission moving forward. The new model allocates the responsibility for making new maps to a bipartisan group of regular old citizens, rather than sitting politicians out to protect their own power.
Some Republicans have embraced a frank attitude for several years. In 2016, Wisconsin Congressman Glenn Grothman expressed his faith in voter ID laws’ ability to influence election results on local television.
While voter suppression didn’t help Romney win in 2012, President Donald Trump carried Wisconsin and Pennsylvania by slim margins in 2016 to win the presidency.
The message from Mississippi to Michigan is plenty clear: Republicans — especially incumbents — intend to keep people from voting, not encourage or facilitate participation. In the Mississippi run-off, the Espy campaign has taken advantage of Hyde-Smith’s honesty to underscore the true intent of established policies.
Hyde-Smith isn’t out to run a fair and free election: her party wants to manipulate the system however possible to its own advantage.
Related front page panorama photo credit: Adapted by WhoWhatWhy from Cindy Hyde-Smith (US Senate).

industry_corpus2: Politics & Administration


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Nikki’s “What’s Cooking Wednesday?”…Peanut Butter Chocolate Chip Bacon Cookies!
Thanks for keeping things interesting, Nik! Love ya!
Previous postField Trip without Mommy….Fun for him, nail biting for me!
When I saw a cookie with bacon, I knew I had to pass it on to my readers. I love any sort of meat based baking. I’m still working on a creamed chip beef cupcake! Wait for that one!
Bacon!?! Really!?!My hubby is going to love these, maybe these are just the thing to motivate him to finish up a few things around the house. Thank you for sharing (and my soon-to-be clean car and non-leaking sink thank you too).

industry_corpus2: Hospitality & Catering


text: This website is maintained by Dr. Heath Rose of the University of Oxford. Currently, it contains links to my research outputs as well as slides and materials from invited talks and conference papers. There are also some archive materials from previously taught courses.


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Cain and Abel - Bible Coloring Pages | What's in the Bible?
A downloadable coloring page showing Cain and Abel from Genesis 4.
DVD 1: What is the Bible?
DVD 1: What is primeval history?


text: Hello, my name is Yoad! I attended high school in both Québec and Nova Scotia, and am currently studying the sciences at McGill. I love tutoring and have been helping my friends and other younger students for a few years now. Why do I like to be a tutor? Well, life is all about learning, and I love answering challenging questions just as much as I like asking them. So, ask away! To be honest, the scariest question that I've ever been asked is "what do you want to do when you're older?" and I still don't know how to answer it! I love to travel and to learn, and when I'm not tutoring or learning, I'm probably exploring, asking questions, reading, or catching up on some well-deserved sleep!


text: 16 If you have sinned, you should tell each other what you have done. Then you can pray for one another and be healed. The prayer of an innocent person is powerful, and it can help a lot.


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On November 19 + 20, Amy Dobson, Nic Carah and I co-convened a symposium at UQ titled ‘Digital Intimate Publics: Identities, Relationships and Value in Social Media Cultures’. We had 26 papers covering a range of topics, platforms, theoretical frameworks, and disciplines. There were strong themes around how digital social media structure intimacy in different kinds of ways, how networked publics might act as counterpublics, and the diverse practices that users enrol to ‘be’ in networked publics.
We talked hook-up apps, Tumblr, Facebook, YouTube, Vine, Instagram, the Zyzz phenomenon, families, metaphors for describing digital ‘spaces’, feminisms, manspreading, digilantism, GamerGate, gender identity, sexualities, mourning, archives, research methods and more more more so much more.
You can find the full program here.
Our intention was to bring together some key players in the study of digital intimate publics in Australia, and I think we were successful. The papers were all really terrific and hung together so well. The two days were thoroughly stimulating, and the plan is now to turn it all into something coherent – perhaps an edited book – if we can.
Thanks to all the presenters, session chairs, brilliant keynotes, UQ’s IASH and School of Communication and Arts for hosting, and my wonderful-amazing-brilliant co-convenors, Amy and Nic.
I’ve archived some tweets below.

industry_corpus2: Technology & Research


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" 3 weeks results. I can't imagine how my skin has improvement. Love it " !
She purchased the Super Enzymes Kit .

industry_corpus2: Biopharmaceuticals


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We live in an era of hatred and intolerance directed against those who do not conform to an increasingly archaic set of “norms” – White, cisgender, male, ethnically and economically privileged. This hatred is stoked by those who would elevate their own power at the expense of another human being’s dignity.
Anti-Transgender “bathroom bills” and the incredibly cruel announcement from President Trump (which could potentially start a purge from the military of well over 5000 openly transgender troops currently serving our country) serve no legitimate purpose. They protect nobody, save nothing, accomplish nothing beyond the undermining of our national security, credibility and moral authority. They exist entirely to bolster the status of politicians who view bigotry as a convenient path to power.
It is an old story, and an intolerable one. It is the story of Dixiecrats, the “Southern Strategy,” “Defense of Marriage” acts, anti-immigrant racism, antisemitism, Islamophobia, continued legal discrimination against the lgbtq community, and much more; the list stretches far too long. Always the method is the same – find a vulnerable group in society, paint them as less deserving of human rights, and therefore less than human, and use them as objects to create societal division. Always the consequences are the same – violence, discord and despair – and in the extreme, genocide.
To my transgender family, friends and neighbors who are suffering today, I give you my support and my solidarity. You have been victimized, not because of who you are, but because of what you are – an easy target. It is wrong on every level, and I pledge myself to your struggle.
I am far from the only one. I only hope you know, in this moment of suffering, the love that is yours, the support you have, and the determination with which we will continue on behalf of your dignity, your freedom, and your rights.
Please do not be silent. Tell us what you need, and we will listen. We must listen. At stake is the soul of humanity.


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This is something we are asked a lot and especially as the industry starts to pick up and we need to re-visit competency in our organisations.
For less experienced assessors or those who have not been assessing for some time, assessor refresher training will be essential. This should be looking at what assessing is about as well as how to assess in your organisation. If you have changed your process at all, you also need to consider refresher training. The other clue that assessor refresher training is needed, would be if you are not getting assessment back or the assessments are not passing your internal verification checks.
However, you do not need to make this an expensive or time consuming process: short, sharp retraining to build confidence in assessing and to refresh on the assessment process in your organisation is the focus.
One of the most useful points to reinforce the training is “is it in anyone’s interest to sign someone off as competent who is not quite ready”.
We can help you with assessor training from short workshops to online courses. We can build in your key messages and assessment process so that the assessors get the most from the training.


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Our work in family law, commercial, and non-personal injury matters is generally billed based on the amount of time we spend doing your work. We require a down payment, sometimes called a "retainer," the amount of which varies depending upon the circumstances of each case. Each month we send out bills reflecting which staff member worked on your case. the specific work done. the date it was done. and what each item of work cost. The time spent working on your case, and expenses associated with your work, are "billed against," that is, subtracted from, the down payment or retainer. If the retainer is exhausted, your bill will reflect a balance due. If money is left in your account, a credit balance will be reflected on your bill. All retainers are placed in a bank account, as required by law, called a "trust account," and are not available for the firm's use until time is actually spent working on your case. Attorneys are not generally allowed to handle family law matters on a contingent basis.
In addition to payment for time spent working on your case, you are generally responsible for costs associated with it. All time-based cases handled by our office are covered by a written fee agreement signed by both client and attorney, which agreement sets forth in detail the responsibilities of both. After both you and the attorney sign this, you will receive a copy of it for your files.
Many personal injury and some commercial (business) cases are billed on a contingent fee basis. This means our client is responsible for the attorney's fee based on a percentage of the recovery made by the attorney for our client. In addition, clients are responsible for the expenses incurred by the attorney in processing the case. All contingent fee cases handled by our office are covered by a written fee agreement, signed by both client and attorney, which agreement sets forth in detail the responsibilities of both. After both you and the attorney sign this, you will receive a copy of it for your files.


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KEPPRA XR® is indicated as adjunctive therapy in the treatment of partial onset seizures in patients 12 years of age and older with epilepsy.
KEPPRA XR is administered once daily. Initiate treatment with a dose of 1000 mg once daily. The once daily dosage may be adjusted in increments of 1000 mg every 2 weeks to a maximum recommended daily dose of 3000 mg/day.
KEPPRA XR tablets are white, oblong-shaped, film-coated extended-release tablets imprinted in red with “UCB 500XR” on one side and contain 500 mg levetiracetam.
KEPPRA XR tablets are white, oblong-shaped, film-coated extended-release tablets imprinted in red with “UCB 750XR” on one side and contain 750 mg levetiracetam.
KEPPRA XR 500 mg tablets are white, oblong-shaped, film-coated tablets imprinted with “UCB 500XR” in red on one side. They are supplied in white HDPE bottles containing 60 tablets (NDC 50474-598-66).
KEPPRA XR 750 mg tablets are white, oblong-shaped, film-coated tablets imprinted with “UCB 750XR” in red on one side. They are supplied in white HDPE bottles containing 60 tablets (NDC 50474-599-66).
The prescriber should be aware that the adverse reaction incidence figures in the following table, obtained when KEPPRA XR was added to concurrent AED therapy, cannot be used to predict the frequency of adverse reactions in the course of usual medical practice where patient characteristics and other factors may differ from those prevailing during clinical trials. Similarly, the cited frequencies cannot be directly compared with figures obtained from other clinical investigations involving different treatments, uses, or investigators. An inspection of these frequencies, however, does provide the prescriber with one basis to estimate the relative contribution of drug and non-drug factors to the adverse reaction incidences in the population studied.
In the controlled clinical study using KEPPRA XR in patients with partial onset seizures, the most frequently reported adverse reactions in patients receiving KEPPRA XR in combination with other AEDs, for events with rates greater than placebo, were irritability and somnolence.
Table 3 lists adverse reactions that occurred in at least 5% of epilepsy patients treated with KEPPRA XR participating in the placebo-controlled study and were numerically more common than in patients treated with placebo. In this study, either KEPPRA XR or placebo was added to concurrent AED therapy. Adverse reactions were usually mild to moderate in intensity.
In the controlled clinical study using KEPPRA XR, 5.2% of patients receiving KEPPRA XR and 2.5% receiving placebo discontinued as a result of an adverse reaction. The adverse reactions that resulted in discontinuation and that occurred more frequently in KEPPRA XR-treated patients than in placebo-treated patients were asthenia, epilepsy, mouth ulceration, rash and respiratory failure. Each of these adverse reactions led to discontinuation in a KEPPRA XR-treated patient and no placebo-treated patients.
Table 4 lists the adverse reactions seen in the controlled studies of immediate-release KEPPRA tablets in adult patients experiencing partial onset seizures. Although the pattern of adverse reactions in the KEPPRA XR study seems somewhat different from that seen in partial onset seizure controlled studies for immediate-release KEPPRA tablets, this is possibly due to the much smaller number of patients in this study compared to the immediate-release tablet studies. The adverse reactions for KEPPRA XR are expected to be similar to those seen with immediate-release KEPPRA tablets.
In controlled clinical studies of immediate-release KEPPRA tablets as adjunctive therapy to other AEDs in adults with partial onset seizures, the most frequently reported adverse reactions, for events with rates greater than placebo, were somnolence, asthenia, infection and dizziness.
Table 4 lists adverse reactions that occurred in at least 1% of adult epilepsy patients treated with immediate-release KEPPRA tablets participating in placebo-controlled studies and were numerically more common than in patients treated with placebo. In these studies, either immediate-release KEPPRA tablets or placebo was added to concurrent AED therapy. Adverse reactions were usually mild to moderate in intensity.
In addition, the following adverse reactions were seen in other well-controlled studies of immediate-release KEPPRA tablets: balance disorder, disturbance in attention, eczema, hyperkinesia, memory impairment, myalgia, personality disorders, pruritus, and vision blurred.
There are insufficient data for KEPPRA XR to support a statement regarding the distribution of adverse experience reports by gender, age and race.
In addition to the adverse reactions listed above for immediate-release KEPPRA tablets, the following adverse events have been identified during postapproval use of immediate-release KEPPRA tablets. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. The listing is alphabetized: abnormal liver function test, choreoathetosis, dyskinesia, erythema multiforme, hepatic failure, hepatitis, leukopenia, neutropenia, pancreatitis, pancytopenia (with bone marrow suppression identified in some of these cases), thrombocytopenia, and weight loss. Alopecia has been reported with immediate-release KEPPRA use; recovery was observed in majority of cases where immediate-release KEPPRA was discontinued.
No significant pharmacokinetic interactions were observed between levetiracetam or its major metabolite and concomitant medications via human liver cytochrome P450 isoforms, epoxide hydrolase, UDP-glucuronidation enzymes, P-glycoprotein, or renal tubular secretion [see CLINICAL PHARMACOLOGY].
A total of 13% of adult patients and 38% of pediatric patients (4 to 16 years of age) treated with immediate-release KEPPRA experienced non-psychotic behavioral symptoms (reported as aggression, agitation, anger, anxiety, apathy, depersonalization, depression, emotional lability, hostility, hyperkinesias, irritability, nervousness, neurosis, and personality disorder), compared to 6% and 19% of adult and pediatric patients on placebo. A randomized, double-blind, placebo-controlled study was performed to assess the neurocognitive and behavioral effects of immediate-release KEPPRA tablets as adjunctive therapy in pediatric patients (4 to 16 years of age). An exploratory analysis suggested a worsening in aggressive behavior in patients treated with immediate-release KEPPRA tablets in that study [see Use in Specific Populations].
One percent of adult patients and 2% of pediatric patients (4 to 16 years of age) treated with immediate-release KEPPRA experienced psychotic symptoms, compared to 0.2% and 2%, respectively, in adult and placebo-treated pediatric patients. In the controlled study that assessed the neurocognitive and behavioral effects of immediate-release KEPPRA in pediatric patients 4 to 16 years of age, 1.6% KEPPRA-treated patients experienced paranoia, compared to no placebo-treated patients. There were 3.1% patients treated with immediate-release KEPPRA who experienced confusional state, compared to no placebo-treated patients [see Use in Specific Populations].
KEPPRA XR can cause hematologic abnormalities. Hematologic abnormalities occurred in clinical trials and included decreases in red blood cell (RBC) counts, hemoglobin, and hematocrit, and increases in eosinophil counts. Decreased white blood cell (WBC) and neutrophil counts also occurred in clinical trials. Cases of agranulocytosis have been reported in the postmarketing setting.
In controlled trials of immediate-release KEPPRA tablets in patients experiencing partial onset seizures, minor, but statistically significant, decreases compared to placebo in total mean RBC count (0.03 x 106/mm³), mean hemoglobin (0.09 g/dL), and mean hematocrit (0.38%), were seen in immediate-release KEPPRA-treated patients.
A total of 3.2% of KEPPRA-treated and 1.8% of placebo-treated patients had at least one possibly significant ( > 2.8 x 109/L) decreased WBC, and 2.4% of KEPPRA-treated and 1.4% of placebo-traeted patients had at least one possibly significant ( > 1.0 x 109/L) decreased neutrophil count. Of the KEPPRA-treated patients with a low neutrophil count, all but one rose towards or to baseline with continued treatment. No patient was discontinued secondary to low neutrophil counts.
In pediatric patients (4 to < 16 years of age), statistically significant decreases in WBC and neutrophil counts were seen in patients treated with immediate-release KEPPRA, as compared to placebo. The mean decreases from baseline in the immediate-release KEPPRA group were -0.4 × 109/L and -0.3 × 109/L, respectively, whereas there were small increases in the placebo group. A significant increase in mean relative lymphocyte counts was observed in 1.7% of patients treated with immediate-release KEPPRA compared to a decrease of 4% in patients on placebo.
In the controlled pediatric trial, a possibly clinically significant abnormal low WBC value was observed in 3% of patients treated with immediate-release KEPPRA, compared to no patients on placebo. However, there was no apparent difference between treatment groups with respect to neutrophil count. No patient was discontinued secondary to low WBC or neutrophil counts.
In the controlled pediatric cognitive and neuropsychological safety study, two subjects (6.1%) in the placebo group and 5 subjects (8.6%) in the immediate-release KEPPRA-treated group had high eosinophil count values that were possibly clinically significant ( ≥ 10% or ≥ 0.7X109/L).
Counsel patients, their caregivers, and/or families that antiepileptic drugs (AEDs), including KEPPRA XR, may increase the risk of suicidal thoughts and behavior and advise patients to be alert for the emergence or worsening of symptoms of depression; unusual changes in mood or behavior; or suicidal thoughts, behavior, or thoughts about self-harm. Advise patients, their caregivers, and/or families to immediately report behaviors of concern to a healthcare provider.
Advise patients that KEPPRA XR may cause changes in behavior (e.g. irritability and aggression). In addition, patients should be advised that they may experience changes in behavior that have been seen with other formulations of KEPPRA, which include agitation, anger, anxiety, apathy, depression, hostility, and psychotic symptoms.
Inform patients that KEPPRA XR may cause dizziness and somnolence. Inform patients not to drive or operate machinery until they have gained sufficient experience on KEPPRA XR to gauge whether it adversely affects their ability to drive or operate machinery.
Patients should be instructed to only take KEPPRA XR once daily and to swallow the tablets whole. They should not be chewed, broken, or crushed. Inform patients that they should not be concerned if they occasionally notice something that looks like swollen pieces of the original tablet in their stool.
Advise patients to notify their healthcare provider if they become pregnant or intend to become pregnant during KEPPRA XR therapy. Encourage patients to enroll in the North American Antiepileptic Drug (NAAED) pregnancy registry if they become pregnant. This registry is collecting information about the safety of antiepileptic drugs during pregnancy. To enroll, patients can call the toll free number 1-888-233-2334 [see Use in Specific Populations].
Rats were dosed with levetiracetam in the diet for 104 weeks at doses of 50, 300 and 1800 mg/kg/day. The highest dose is 6 times the maximum recommended daily human dose (MRHD) of 3000 mg on a mg/m² basis and it also provided systemic exposure (AUC) approximately 6 times that achieved in humans receiving the MRHD. There was no evidence of carcinogenicity. In mice, oral administration of levetiracetam for 80 weeks (doses up to 960 mg/kg/day) or 2 years (doses up to 4000 mg/kg/day, lowered to 3000 mg/kg/day after 45 weeks due to intolerability) was not associated with an increase in tumors. The highest dose tested in mice for 2 years (3000 mg/kg/day) is approximately 5 times the MRHD on a mg/m² basis.
No adverse effects on male or female fertility or reproductive performance were observed in rats at oral doses up to 1800 mg/kg/day (6 times the maximum recommended human dose on a mg/m² or systemic exposure [AUC] basis).
KEPPRA XR levels may decrease during pregnancy [see WARNINGS AND PRECAUTIONS].
Oral administration of levetiracetam to female rats throughout pregnancy and lactation led to increased incidences of minor fetal skeletal abnormalities and retarded offspring growth pre-and/or postnatally at doses ≥ 350 mg/kg/day (equivalent to the maximum recommended human dose of 3000 mg [MRHD] on a mg/m² basis) and with increased pup mortality and offspring behavioral alterations at a dose of 1800 mg/kg/day (6 times the MRHD on a mg/m² basis). The developmental no effect dose was 70 mg/kg/day (0.2 times the MRHD on a mg/m² basis). There was no overt maternal toxicity at the doses used in this study.
Oral administration of levetiracetam to pregnant rabbits during the period of organogenesis resulted in increased embryofetal mortality and increased incidences of minor fetal skeletal abnormalities at doses ≥ 600 mg/kg/day (4 times MRHD on a mg/m² basis) and in decreased fetal weights and increased incidences of fetal malformations at a dose of 1800 mg/kg/day (12 times the MRHD on a mg/m² basis). The developmental no effect dose was 200 mg/kg/day (equivalent to the MRHD on a mg/m² basis). Maternal toxicity was also observed at 1800 mg/kg/day.
Treatment of rats with levetiracetam during the last third of gestation and throughout lactation produced no adverse developmental or maternal effects at oral doses of up to 1800 mg/kg/day (6 times the MRHD on a mg/m² basis).
Safety and effectiveness in pediatric patients 12 years of age and older has been established based on pharmacokinetic data in adults and adolescents using KEPPRA XR and efficacy and safety data in controlled pediatric studies using immediate-release KEPPRA [see ADVERSE REACTIONS, CLINICAL PHARMACOLOGY, and Clinical Studies].
A 3-month, randomized, double-blind, placebo-controlled study was performed to assess the neurocognitive and behavioral effects of immediate-release KEPPRA as adjunctive therapy in 98 pediatric patients with inadequately controlled partial seizures, ages 4 to 16 years (KEPPRA N=64; placebo N=34). The target dose of immediate-release KEPPRA was 60 mg/kg/day. Neurocognitive effects were measured by the Leiter-R Attention and Memory (AM) Battery, which assesses various aspects of a child's memory and attention. Although no substantive differences were observed between the placebo- and KEPPRA-treated groups in the median change from baseline in this battery, the study was not adequate to assess formal statistical non-inferiority between the drug and placebo. The Achenbach Child Behavior Checklist (CBCL/6-18), a standardized validated tool used to assess a child's competencies and behavioral/emotional problems, was also assessed in this study. An analysis of the CBCL/6-18 indicated a worsening in aggressive behavior, one of the eight syndrome scores, in patients treated with KEPPRA [see WARNINGS AND PRECAUTIONS].
The effect of KEPPRA XR on renally impaired patients was not assessed in the controlled study. However, it is expected that the effect on KEPPRA XR-treated patients would be similar to the effect seen in controlled studies of immediate-release KEPPRA tablets. Clearance of levetiracetam is decreased in patients with renal impairment and is correlated with creatinine clearance [see CLINICAL PHARMACOLOGY]. Dose adjustment is recommended for patients with impaired renal function [see DOSAGE AND ADMINISTRATION].
Bioavailability of KEPPRA XR tablets is similar to that of the immediate-release KEPPRA tablets. The pharmacokinetics (AUC and Cmax) were shown to be dose proportional after single dose administration of 1000 mg, 2000 mg, and 3000 mg extended-release levetiracetam. Plasma half-life of extended-release levetiracetam is approximately 7 hours.
Levetiracetam is almost completely absorbed after oral administration. The pharmacokinetics of levetiracetam are linear and time-invariant, with low intra- and inter-subject variability. Levetiracetam is not significantly protein-bound ( < 10% bound) and its volume of distribution is close to the volume of intracellular and extracellular water. Sixty-six percent (66%) of the dose is renally excreted unchanged. The major metabolic pathway of levetiracetam (24% of dose) is an enzymatic hydrolysis of the acetamide group. It is not liver cytochrome P450 dependent. The metabolites have no known pharmacological activity and are renally excreted. Plasma half-life of levetiracetam across studies is approximately 6-8 hours. The half-life is increased in the elderly (primarily due to impaired renal clearance) and in subjects with renal impairment.
An open label, multicenter, parallel-group, two-arm study was conducted to evaluate the pharmacokinetics of KEPPRA XR in pediatric patients (13 to 16 years old) and in adults (18 to 55 years old) with epilepsy. KEPPRA XR oral tablets (1000 mg to 3000 mg) were administered once daily with a minimum of 4 days and a maximum of 7 days of treatment to 12 pediatric patients and 13 adults in the study. Dose-normalized steady-state exposure parameters, Cmax and AUC, were comparable between pediatric and adult patients.
The disposition of immediate-release levetiracetam was studied in adult subjects with varying degrees of renal function. Total body clearance of levetiracetam is reduced in patients with impaired renal function by 40% in the mild group (CLcr = 50-80 mL/min), 50% in the moderate group (CLcr = 30-50 mL/min) and 60% in the severe renal impairment group (CLcr < 30 mL/min). Clearance of levetiracetam is correlated with creatinine clearance.
In anuric (end stage renal disease) patients, the total body clearance decreased 70% compared to normal subjects (CLcr > 80mL/min). Approximately 50% of the pool of levetiracetam in the body is removed during a standard 4- hour hemodialysis procedure [see DOSAGE AND ADMINISTRATION].
In vitro data on metabolic interactions indicate that levetiracetam is unlikely to produce, or be subject to, pharmacokinetic interactions. Levetiracetam and its major metabolite, at concentrations well above Cmax levels achieved within the therapeutic dose range, are neither inhibitors of, nor high affinity substrates for, human liver cytochrome P450 isoforms, epoxide hydrolase or UDPglucuronidation enzymes. In addition, levetiracetam does not affect the in vitro glucuronidation of valproic acid.
Probenecid, a renal tubular secretion blocking agent, administered at a dose of 500 mg four times a day, did not change the pharmacokinetics of levetiracetam 1000 mg twice daily. Css max of the metabolite, ucb L057, was approximately doubled in the presence of probenecid while the fraction of drug excreted unchanged in the urine remained the same. Renal clearance of ucb L057 in the presence of probenecid decreased 60%, probably related to competitive inhibition of tubular secretion of ucb L057. The effect of immediate-release KEPPRA tablets on probenecid was not studied.
The effectiveness of KEPPRA XR as adjunctive therapy in partial onset seizures in adults was established in one multicenter, randomized, double-blind, placebo-controlled clinical study in patients who had refractory partial onset seizures with or without secondary generalization. This was supported by the demonstration of efficacy of immediate-release KEPPRA tablets (see below) in partial seizures in three multicenter, randomized, double-blind, placebo-controlled clinical studies in adults, as well as a demonstration of comparable bioavailability between the XR and immediate-release formulations [see CLINICAL PHARMACOLOGY] in adults. The effectiveness for KEPPRA XR as adjunctive therapy in partial onset seizures in pediatric patients, 12 years of age and older, was based upon a single pharmacokinetic study showing comparable pharmacokinetics of KEPPRA XR in adults and adolescents [see CLINICAL PHARMACOLOGY]. All studies are described below.
Study 2 was a double-blind, placebo-controlled, parallel-group study conducted at 41 sites in the United States, comparing immediate-release KEPPRA 1000 mg/day (N=97), immediate-release KEPPRA 3000 mg/day (N=101), and placebo (N=95), given in equally divided doses twice daily. After a prospective baseline period of 12 weeks, patients in Study 2 were randomized to one of the three treatment groups described above. The 18-week treatment period consisted of a 6-week titration period, followed by a 12-week fixed dose evaluation period, during which concomitant AED regimens were held constant. The primary measure of effectiveness in Study 2 was a between-group comparison of the percent reduction in weekly partial seizure frequency relative to placebo over the entire randomized treatment period (titration + evaluation period). Secondary outcome variables included the responder rate (incidence of patients with ≥ 50% reduction from baseline in partial onset seizure frequency). The results of Study 2 are displayed in Table 6.
The percentage of patients (y-axis) who achieved ≥ 50% reduction from baseline in weekly partial onset seizure frequency over the entire randomized treatment period (titration + evaluation period) within the three treatment groups (x-axis) in Study 2 is presented in Figure 1.
The first period of the study (Period A) was designed to be analyzed as a parallel-group study. After a prospective baseline period of up to 12 weeks, patients in Study 3 were randomized to one of the three treatment groups described above. The 16-week treatment period consisted of the 4-week titration period followed by a 12-week fixed dose evaluation period, during which concomitant AED regimens were held constant. The primary measure of effectiveness in Study 3 was a between group comparison of the percent reduction in weekly partial seizure frequency relative to placebo over the entire randomized treatment period (titration + evaluation period). Secondary outcome variables included the responder rate (incidence of patients with ≥ 50% reduction from baseline in partial onset seizure frequency). The results of the analysis of Period A are displayed in Table 7.
The percentage of patients (y-axis) who achieved ≥ 50% reduction from baseline in weekly partial onset seizure frequency over the entire randomized treatment period (titration + evaluation period) within the three treatment groups (x-axis) in Study 3 is presented in Figure 2.
The comparison of immediate-release KEPPRA 2000 mg/day to immediate-release KEPPRA 1000 mg/day for responder rate in Study 3 was statistically significant (P=0.02). Analysis of the trial as a cross-over study yielded similar results.
Study 4 was a double-blind, placebo-controlled, parallel-group study conducted at 47 centers in Europe comparing immediate-release KEPPRA 3000 mg/day (N=180) and placebo (N=104) in patients with refractory partial onset seizures, with or without secondary generalization, receiving only one concomitant AED. Study drug was given in two divided doses. After a prospective baseline period of 12 weeks, patients in Study 4 were randomized to one of two treatment groups described above. The 16-week treatment period consisted of a 4-week titration period, followed by a 12-week fixed dose evaluation period, during which concomitant AED doses were held constant. The primary measure of effectiveness in Study 4 was a between group comparison of the percent reduction in weekly seizure frequency relative to placebo over the entire randomized treatment period (titration + evaluation period). Secondary outcome variables included the responder rate (incidence of patients with ≥ 50% reduction from baseline in partial onset seizure frequency). Table 8 displays the results of Study 4.
The percentage of patients (y-axis) who achieved ≥ 50% reduction from baseline in weekly partial onset seizure frequency over the entire randomized treatment period (titration + evaluation period) within the two treatment groups (x-axis) in Study 4 is presented in Figure 3.
500 mg KEPPRA XR tablets are white, oblong-shaped, film-coated tablets marked with “UCB 500XR” in red on one side.
750 mg KEPPRA XR tablets are white, oblong-shaped, film-coated tablets marked with “UCB 750XR” in red on one side.
are pregnant or planning to become pregnant. It is not known if KEPPRA XR will harm your unborn baby.
You and your healthcare provider will have to decide if you should take KEPPRA XR while you are pregnant. If you become pregnant while taking KEPPRA XR, talk to your healthcare provider about registering with the North American Antiepileptic Drug Pregnancy Registry. You can enroll in this registry by calling 1-888-233-2334. The purpose of this registry is to collect information about the safety of KEPPRA XR and other antiepileptic medicine during pregnancy.
Call your doctor for medical advice about side effects. You may also report side effects to FDA at 1-800FDA-1088.
This Medication Guide summarizes the most important information about KEPPRA XR. If you would like more information, talk with your healthcare provider. You can ask your pharmacist or healthcare provider for information about KEPPRA XR that is written for health professionals. You can also get information about KEPPRA XR at www.keppraxr.com or call 1-(844) 599-CARE (2273).


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The leader of Israel’s Blue and White party, Benny Gantz, told a group of advisors that he would not rule out a unity government with Benjamin Netanyahu after the April elections.
Responding to the reports this morning, Gantz said: “The remarks in the recording were made before the full details of the severe charges against Netanyahu were revealed, and definitely before it turned out he received NIS 16 million in a round-trip trade on the submarines and lied to the public on serious security matters. I am saying, not in an anonymous recording but openly and in my voice: I won’t sit with Netanyahu in the government”.
Yesterday the Blue and White Party called for a state inquiry into Netanyahu’s alleged role and profiteering in the so-called submarine affair, called “Case 3000”. Several close associates of the Prime Minister are suspected to have received illicit bribes as part of the multi-billion-shekel state purchase of naval vessels from Germany.


text: Delivery and installation of decorative moldings and rosettes. The transition between the wall and the ceiling are used ceiling coving. Beading is created wall bar with connecting elements and corners. The shoes are lined with chandeliers, ceiling rosettes.


text: When it comes to Chicago media planning agencies, look no further than PR Hacker Chicago. Our Chicago public relations firm has offices on bustling Kinzie Street just next door to the House of Blues. If you’re looking for a national agency with a local presence to help you with your media planning needs, look no further than PR Hacker Chicago.


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Is not crashing the easy part?
Disclaimer: The following post contains only my personal opinions and not those of my employer.
Cars, and the industry that builds, sells and services them, have changed before our eyes. We can see every day how Autonomous, Connected, Electric and Shared technologies (ACES) are remaking our cities.
Our ReachNow members already experience three of those four ideas. Every car in our fleet is a Shared asset. That removes the need for everyone in the city to have their own private car on the road or taking up a parking space. Cars in our services, along with most new cars sold today, are already Connected. Communication to the Internet cloud services allows users to find, unlock and rent our cars at any time. Many of the most exciting new cars are Electric. Before EVs can become ubiquitous most cities will need to expand public charging infrastructure.
So what about Autonomous? How soon will you be riding in style while a computer does all the driving? Right now autonomous cars are not ready for general availability. The technology is not ready. Yet.
Many companies, from automotive leaders and technology stalwarts to brand new startups, are developing autonomous car technology, yet no system is ready for all driving situations. When you buy or rent a car today, you know that car safe to drive day or night, rain or shine, so long as the driver is attentive and uses their best judgement. You can’t say that yet about an autonomous car whose driver is not a person but a program.
Some observers remain deeply skeptical about whether an AI can drive a car in all situations. That’s understandable at this point in autonomous vehicle development. Everyone wants to feel safe. These cars, when faced with the same situations that good human drivers often misjudge, must react to protect those inside and outside the car.
Even if the tech were ready, as a society we have a lot of decisions to make. What are the licensing and behavior rules for passengers in an autonomous car? How will governments handle regulating these new vehicles whether privately owned or part of a shared fleet?
I’m less concerned whether we can develop the technologies to deploy self-driving cars. GPS data and sensors in today’s cars can already help us pinpoint potholes and slick road conditions. Advancements in miniaturization of senors that enable the car to “see” are accelerating. Real time processing of the input, with ever smaller computing systems almost here. Data collected from test fleets and pilot programs will help to teach these systems how best to analyze the road around them. Soon not crashing will be the “easy” part.
I’ve spent my career building software services for consumers. In my experience, the hard hard problem isn’t what happens outside the car, but inside.
Seems simple, right? But where exactly is “right here”? Is the car going to use a vision system to interpret where you’re pointing? There’s no wheel to turn. The doors are locked for your safety, so you can’t hop out. You might be stuck repeating the same voice command over and over until the car complies.
Humans can (generally) understand what you want and need. Language, empathy and experience make it easier to interact with a person in the front seat. That’s despite the examples of bad trips we’ve all had with frustrating drivers.
Now imagine you have just broken your foot and are using crutches while it heals. A human driver would understand it will take you more time and more room to get out of the car. The best drivers will at least make the offer to come assist you. How will the autonomous car “see” your current situation? How will it handle someone who is older or has mobility issues?
Think back to the simple request, “Just pull up right here.” How would you rate the driver that ignored your request? Unless the car AI react to basic consumer commands, who will trust the driving safety of the system?
I’m not here to say that we shouldn’t build autonomous cars. Far from it. The improvements in traffic efficiency and economy of autonomous electric fleets are critical for our increasingly dense urban neighborhoods. We need autonomous cars to be part of the transportation solution and we need them soon. Still the most difficult problem we have to solve is passenger experience feels responsive, safe and secure.
Too often people think about a future self-driving car as another place to watch Netflix. Of course we’ll be able to make new use of time we’d have otherwise spent focused on the road. The passenger experience inside an autonomous car can’t only be about finding new screen time. It has to be about creating something that is responsive, equitable and empathetic no matter who might taking the next trip.
Next Post Maybe not crashing IS the hard part?

industry_corpus2: Automobiles


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VBScript WebDriver 1.0.0 download by Oscar Henry Tejera vbscript WebDriver is designed to provide a simple binding for Selenium 2, which includes its full functionality.
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