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NEW YORK: Amazon.com Inc, Berkshire Hathaway Inc and JPMorgan Chase & Co said on Tuesday they will form a company to cut health costs for hundreds of thousands of their employees, setting up a major challenge to an inefficient US healthcare system.
The move by three of the best-known US business leaders — Amazon’s Jeff Bezos, Berkshire’s Warren Buffett and JPMorgan’s Jamie Dimon — would take on the world’s most expensive healthcare system, whose mounting costs have hurt corporate profit.
Shares of US healthcare companies fell across the board. The new, not-for-profit venture will initially focus on technology for “simplified, high-quality and transparent healthcare” for their more than 500,000 US employees, the companies said.
They did not elaborate on their strategy, but said they are searching for a chief executive officer.
“The ballooning costs of healthcare act as a hungry tapeworm on the American economy,” said Berkshire Hathaway Chairman and CEO Buffett. “Our group does not come to this problem with answers. But we also do not accept it as inevitable.” US healthcare spending has been increasing annually faster than inflation, and in 2017 accounted for 18 per cent of the economy.
The three CEOs plan for their companies to be the only clients of the joint venture, the person said.
However, they intend to share the strategies and technology they ultimately develop to reduce costs for the economy and the government.
Traditional healthcare players have tried to reduce costs without losing their profit margins.
Most recently, pharmacy network CVS Health Corp reached a $69 billion deal to buy insurer Aetna Inc, arguing their combination could save money for the nation’s employers.
Investors in the sector expect Amazon will become a major disruptor of healthcare, just as it has done in the retail industry, fuelled by media reports in recent months that the company was considering entering the pharmacy business.
Teaming up with JPMorgan, the biggest US bank, and Berkshire, the third-largest public company globally and an insurance provider, offers new opportunities to shake up the industry, analysts said.
For example, JPMorgan could help shape new payment models for consumers and providers, and provide cost data.
CEO Dimon has for years expressed concerns about rising healthcare costs.

industry_corpus2: Health & Medicine


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Reliable SEO is what you need for very first page rankings, even more website traffic & enhanced sales. We have a group of specialist SEO experts that sculpt a fantastic SEO method with a blend of social signals & content advertising and marketing initiatives. From on page & off page optimization to placing your had media & material web links in an proper placement, we make your website completely SEO pleasant for greater engagement, even more shares & important gained media also. Our team additionally keeps track of analytics & maintains well with the current Google algorithm updates & standards to supply intelligent internet marketing solutions.
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industry_corpus2: Computing & Telecommunications


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Total sheep and goat meat production reached 10.9 kt in 2016 in Zambia, according to Faostat. This is 1.1 % less than in the previous year.
Historically, total sheep and goat meat production in Zambia reached an all time high of 11.0 kt in 2015 and an all time low of 0.648 kt in 1961. When compared to Zambia's main peers, total sheep and goat meat production in Angola amounted to 23.9 kt, 63.6 kt in Tanzania, 23.5 kt in Zimbabwe and 21.1 kt in Dem. Republic of the Congo in 2016.
Zambia has been ranked 97th within the group of 167 countries we follow in terms of total sheep and goat meat production, 1 places above the position seen 10 years ago.

industry_corpus2: Agriculture & Fisheries


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Summer greetings from Disconnected HQ. We thought it was time for a wee update on our forthcoming convention plans and a teaser or two about the new comics we’ll be publishing later this year.
Firstly, a plug for a comic con that we sadly can’t attend this year: Melksham. You’ve probably never heard of Melksham but it’s a great little town in Wiltshire, between Bath and Swindon, and it has the Finest Comic Convention of the Year. Trust us! We’ve been each year and seen the show grow from one day to two, taking in more of the town each time and always with a great line-up of guests, a wonderful atmosphere and some of the nicest volunteers and visitors that we’ve ever met. Melksham Comic Con is on Saturday 29 and Sunday 30 August at the Assembly Hall – you can buy tickets in advance at http://melkshamcomiccon.com/.
October will see us returning to Kendal for the Lakes International Comic Arts Festival. We’ve talked before about this one as it’s a firm favourite. The Con really takes over the town, usually theming at least one pub, with workshops and talks in bookshops and cafes and some stellar guests. We’ll be launching a new book at this year’s Lakes show – something a little different from Disconnected and something that we’re VERY EXCITED to be producing. I can’t tell you any more just yet but here’s something from the book from artist Conor Boyle. We’ll be posting more soon!
You can track us down at LICAF in the Clock Tower in Kendal on 17 and 18 October. You can also find the full programme for the festival at http://issuu.com/lakesinternationalcomicartfestival/docs/licaf_programme_2015 (56 pages!!!).
Last but not least, we can confirm that we’ll be at ThoughtBubble again this year (14/15 November, Royal Armouries, Leeds). We’ll be in the Marquee with some lovely people (have a look at some of our co-Marquee-dwellers here). ThoughtBubble is the mummy of conventions, particularly if you’re interested in independent comics: it’s absolutely kid-in-sweet-shop-tastic. And we’ll have a little something for you at ThoughtBubble too – something that many of you have been waiting for…. Yes, more eagerly awaited than the new Star Wars, it’s the return of the Sentient Zombie Space Pigs….
As always, you can keep an eye on what we’re up to on the @DisconnectedPrs Twitter feed, which will get busier as the cons get closer. And you can pick up copies of our books at http://www.comicsy.co.uk/disconnectedpress/ or by dropping us an email to hello@disconnectedpress.co.uk.
Post-election and with cuts abounding from George Osborne’s Summer Budget (tax cuts if your estate is worth more than £1m; benefit cuts if you’ve got bugger all), we’ve decided to reduce the cost of political satire anthology CROSS to £5.
CROSS was compiled before the last election and features work from creators including Rob Williams, Mary Talbot, SICBA award winner Emma Beeby, Vertigo writer David Baillie and many many more. It was our rallying call to encourage people to engage with politics; the message remains but the specifics (voting) are now a little past their sell by date (the appearances of Messrs Clegg, Miliband and Farage show that some things have changed since May).
Anyhoo, if you would like 64 pages of poking sticks at the establishment, featuring some fantastic artwork and great storytelling, simply pop on over to our Comicsy shop and order your copy!
When did you last see your vote?
You know, your vote. You used it a couple of years ago when you voted in your local council elections (well, one in three of you did). More likely, you used it five years ago to help create a very curious coalition (two out of three of you voted that time).
You get to use it again in just over three months’ time. It’s quite useful: it’s the only legitimate way we have of overthrowing a Government if we don’t like it. In the interests of balance, it’s also the only legitimate way of ensuring that a Government you do like stays in power.
Anyhoo, the point is this: voter registration has changed. Up until last year, one person per household filled in a form which said who lived there and was eligible to vote.
Now, every individual in the household has to fill in their own form. This has been in the works for a decade, and is a good way of making sure that we don’t miss anyone.
Except the process of change has lost a million voters.
Here at Disconnected Press, we care about votes. Underlying the sarcasm and the venom that populates our political satire anthology CROSS is a core message: use your vote.
In order to use your vote, you need to be registered. So go and dig through that pile of junk mail you’ve been ignoring and make sure you are. Spread the word too, particularly on National Voter Registration Day on February 5th – you can find out more about that at http://bitetheballot.co.uk/nvrd/.
What you do with your vote is entirely up to you. Just don’t lose it….

industry_corpus2: Film & Entertainment


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You know that we’re all about child safety at Blinds.com; today we’re taking it out of the windows and onto the streets!
Emergency planning! – Talk out scenarios (separated from the crowd, injuries, stranger danger) so when / if the time comes, they’ll know how to act and who to call for help.
Keep your home well-lit – while a dark imposing house sure is spooky, most parents won’t be too keen on sending their little ghost to your doorstep. Go creative with creepy lighting and perhaps a welcome sign at your gate.
Katie Laird (aka: happykatie) is the Blinds.com PR and Social Media Marketing Manager. But, more importantly, she's a home design obsessed Web geek with a love for Mid-Century Modern furniture, stained glass and DIY / crafty projects she can work on with her family over a bottle of homemade root beer. Find her Tweeting at @happykatie -- and pinning like nobody's business at @happykatie.

industry_corpus2: Others


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Markets opened the day lower as political uncertainty following the TMC withdrawal of support to the UPA government weighed on sentiments.
The Sensex was trading lower by 109 points at 18,386 points, while the Nifty was trading lower by 37 points at 9.20 am IST. Among the top gainers in trade today were ITC, BPCL, HCL Tech and Maruti Suzuki.
Shares of State Bank of India were trading lower by Rs 45, following the bank's decision to cut the base lending rate by 25 basis points.
Shares of Jet Airways surged after the company was reportedly in talks with Etihad Airways for a minority stake in the company.
High beta names like metal and banking stocks lost ground in trade today with Axis Bank, ICICI Bank, Jindal Steel, Sterlite and Hindalco all shedding gains in early trade. Heavyweight Reliance Industries was down 1% in trade.
Steel conglomerate Tata Steel saw its share price decline even after the company received a Letter of Intent from Eiffage Rail for the supply of high-quality rail for a new 182 km (113 mile) high-speed line in France.
Asian shares were all trading deeply in the red with Singapore's Strait Times, Hong Kong's Hang Sang, Japanese Nikkei and the Korean Kospi all down.
Markets are expected to continue to show volatility following the political uncertainty. Volumes are also expected to remain low today as a Bharat bandh has been declared by the opposition parties.

industry_corpus2: Finance & Economics


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Is kosher nacho cheese Kosher? in Israel.
Find if kosher nacho cheese is kosher in Israel Is it kosher? app designed to help people find kosher food in any shop worldwide.


text: This 12x12 double sided paper has Vintage/Retro Telephones on the frontside while the reverse side has a sold Aqua print. This is part of the Life in Color Collection by BoBunny Press. Look for coordinating Designer Papers, Noteworthy Die Cuts, 3D Layered Stickers, Journaling Cards and Stickers.


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ASTM steel 06625 steel 2.4856 Bar Nickel Alloy 625 - Harsh Steel Inconel 625 is a consumption and oxidation safe nickel alloy that is utilized both for its high quality and remarkable aqueous erosion safety.
steeltubes.co.in› …› Pipe & Tube Fittings Description. Alloy 625 Socket Weld Fittings Manufacturers & Suppliers – Inconel Alloy 625 Socket Weld Fittings Metline is a specialist manufacturer of Inconel® 625 / N06625 socket weld fittings in size range of 1/2″ NB to 4″ NB 3000#, 6000#, 9000#, manufactured as per ANSI B16.11 & ASTM B564.
B564 steel 06625 steel 2.4856 Bar manufacturer in China ,we are professional B564 steel 06625 steel 2.4856 Bar suppliers and distributor ,if you need B564 steel 06625 steel 2.4856 Bar price and application ,please contact us.
Inconel 625 Seamless Tube , ASTM B444 GR.2 Gr.1 INCONEL 625(N06625 / 2.4856) heat exchanger / boiler tube . YUHONG GROUP deal with Stainless/Duplex/ Nickel steel seamless pipe and tube already more than 10 years, every year sell more than 80000 tons of S tainless/Duplex/ Nickel steel seamless pipe and tube. Our client already cover more than 45 countries.
Inconel 625 Tube Fittings Siddhagiri Metals and Tubes is a leading supplier, manufacturer and exporter of Inconel 625 Compression Tube Fittings including Inconel 625 Compression Fittings, Inconel 625 Instrumentation Fittings and Inconel 625 Ferrule Fittings.

industry_corpus2: Manufacturing


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How does the CanadaVet Application Reminder System work?
Is Shopping with CanadaVet secure?
Does CanadaVet sell Interceptor, Sentinel, Capstar or Program?
Are the products I buy from CanadaVet genuine?
Do you sell Heartgard Chewables or just Heartgard Tablets?
Heartgard is expensive, do you have a generic alternative?
Do you sell K9 Advantix?
I want to change my order, what do I need to do?
I'm not based in the USA (e.g. Europe, UK) , will I have to pay customs duty, VAT or GST on my order?
I tried entering a coupon code and it did not work, what should I do?
Why does my card show a "foreign card fee" as well as my payment to you?
My card keeps being declined, but I know my card is not over the limit. What can I do?
How much does postage & handling cost?
I can't find my previous orders on my order history?


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Ferry boats cross Bali Strait to carry Indonesians to Ketapang port, East Java, from Gilimanuk port, West Bali, Indonesia (File Photo - August 27, 2011).
Indonesia's scenic island Bali will be the setting for the East Asia summit in November, of which President Obama is expected to attend. The country’s premier tourist destination is seeking to capitalize on business tourism after a difficult decade marked by two terrorist attacks and the SARS and bird flu epidemics.
In Kendran village, in the center of Bali, everything is green. Delicate rice sprouts peek from terraced fields. Dense thickets of banana trees encroach the side of a road. Shaded gardens decorate the entrance of temples and houses. But despite its lush appearance, water in the village is in short supply.
Made Ruta, one of Kendran’s rice farmers, explains that the public water distribution company PDAM owns two of the three water sources located on the village’s land. He says the local government demanded it prioritize the nearby tourist town of Ubud for water distribution. Thus, he says, for the past five years there has not been enough water during the dry season to properly irrigate all rice fields.
Environmentalist Wayan Gendo Suarna, who chairs the Bali chapter of the Indonesian NGO Walhi, warns that a water crisis looms.
Wayan says that although consumption is highest in the South of the island, where the tourist facilities are located, there are no water resources there. Shortages now exist in the rural and mountainous North, closer to the water sources. He says local policies dictate that the tourism industry, which contributes most to the island’s economy, should come before the needs of rice farmers.
Made Ruta, the Kendran farmer, says the situation is unfortunate.
Nowadays, he says, there’s not much harmony left in the village. In the peak of the dry season farmers may creep at night into their neighbor’s fields to steal water. Because of this problem and the lure of better jobs in the tourist industry, many farmers are tempted to sell their land.
Bayu Susila, head of the environment NGO Bali Fokus, says that this is felt throughout Bali.
Bali’s Hindu culture and unique agrarian lifestyle is the island’s main tourist attraction. So Bayu warns that the erosion of the traditional way of life could have dire consequences.
Bali is a small island, about the size of the tiny U.S. state of Rhode Island. With more than three-and-a-half million residents and about two million tourists a year, officials say Bali is severely overcrowded.
In southern Bali's busy streets, traffic jams choke the towns. Waste is so poorly managed that during the rainy season, when rivers swell, garbage dumped throughout the island end up layering the long, white sand beaches.
Ngurah Wijaya, chairman of the Bali Tourism Board says there is not enough electricity, water and roads to accommodate the island’s successful industry.
“Bali has nothing. The only work we can do here is tourism, so it has to continue," said Wijaya. "We’ve proposed to the government, and the government agreed, to have a moratorium on building new accommodation in Bali. The government should build again the infrastructure in Bali such as electricity, water, accessibility and garbage.
But there is no indication the government will impose a moratorium any time soon. A huge conference center is scheduled to be built soon to accommodate a 2013 APEC summit. Several other big projects are scattered throughout the south of the island. A large Indonesian chain is building another resort on the luxurious compound of Nusa Dua on Geger Beach.
At the base of a high pile of rubble that creeps onto the beach, an extended Balinese family is attending a ceremony. They all gather once every six months to worship the spirits of their ancestors, who they believe are represented by a holy rock that barely peeks from the high tide. Soon, access to this beach will be restricted to the hotel’s clients. But family members say they do not mind.
They say that they are happy there is yet another resort to be built here. The more tourists the better, they say, as they bring cash and good jobs along with them. So, as long as the hotel management lets them hold their colorful ceremony every six months, as has already been agreed, they welcome the new resort with open arms.
The successful tourism industry has made Bali one the richest provinces in Indonesia. Although few Balinese are willing to slow down the pace of development, there are some who worry that the growth may eventually overwhelm the natural beauty that drew people here in the first place.

industry_corpus2: Travel & Geography


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Most nursing homes in Eau Claire, WI offer skilled nursing, post acute care and inpatient rehab for the elderly. In order to find the right nursing home for you, our experienced local advisors in Eau Claire, WI will walk you through the process.
Call your local advisor in Eau Claire, WI and get free personalized service.


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Pet Wize has been serving the Tampa Bay area for over 35 years. We are an independently owned pet supply store and we offer competitive prices. We have been a local source for healthy grain-free pet foods, and supplies since 1983.
Our large selection of healthy, grain-free and natural pet foods make us the best choice for your pet. We carry raw, organic, holistic, high quality foods to promote optimal pet health. Our EVERYDAY DISCOUNTED PRICES on premium, quality, natural dog and cat food as well as our friendly, knowledgeable staff have kept loyal customers coming back for decades.
Shop our large selection of treats, toys and fashion accessories for your four legged friends. We also offer full service grooming for your pet 7 days a week.
At Pet Wize, we offer you the best of both worlds. Online pricing and a helpful, educated staff. We are always here to answer any of your questions. Stop in today and compare our prices. We think you will be pleasantly surprised.
Founded in April of 1983, Pet Wize has been providing Tampa Bay pet owners the highest quality foods, with brands such as Fromm, Nutri-Source, Blue Buffalo, Natural, Earthborn, and others.
The owner, Nick, has been in the pet business for over 35 years, and is passionate about feeding quality, nutritious foods. He knows what it takes to keep your pets healthy and happy. With recommendations on food, proper care, and training, he is an invaluable resource for any pet owner.
Very friendly and knowledgeable staff that takes the time to answer your questions!! I highly recommend Pet Wize for all your pet needs!!
I love taking my dog here to get groomed! It's the only place that can clip his nails (my vet has to sedate him). The staff and groomers are very nice and they have a great selection of dog treats and chews.
The staff is so nice and considerate! After I took my rescue here to get groomed, his bald spot grew in and his skin stopped being so flakey. I told him how my dog was a rescue and the condition he was found in and the owner game me treats and food to try for free.
Nick the owner was very gracious when we popped in the first time when we were browsing the dog food area. He allowed us to take home some food and treats free or charge; amazing gesture. The staff was super friendly, and did an A+ job with the grooming.
I am extremely picky about where I take my English Bulldog. I have been to every pet shop anywhere near here, and this is the only one I go to. Always clean and great prices on grooming. Overall, the absolute best place to take your dog!


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Here at Drain Cleaning Guys, we're there to meet your standards when it comes to Drain Cleaning in Beulah, MI. You are looking for the most innovative modern technology around, and our crew of well trained contractors will offer just that. We will apply first-rate supplies and money conserving practices to make sure that you get the finest solutions at the greatest value. Call us today by dialing 800-964-5990 and we will be glad to discuss the options, answer your concerns, and arrange a scheduled appointment to get started planning the project.
Saving cash is an important part of any project. But, conserving money should not signify that you sacrifice quality on Drain Cleaning in Beulah, MI. We offer the very best quality even while costing you less. Any time you deal with our staff, you'll receive the advantages of our own valuable experience and top standard supplies to make certain that the project can last even while saving your time and resources. For instance, we take care to avoid expensive errors, complete the job promptly to help save hours, and be sure that you will enjoy the best savings on products and work. Save your time and funds by getting in touch with Drain Cleaning Guys right now. Call 800-964-5990 to speak with our customer service agents, right now.
When you're thinking of Drain Cleaning in Beulah, MI, you've got to be informed to come up with the most effective decisions. We will not let you make ill advised judgments, as we know what we are working at, and we ensure you understand what to be expecting with the project. You're not going to deal with any sort of unexpected surprises when you use Drain Cleaning Guys. Start by talking over your job with our customer support associates when you dial 800-964-5990. We'll go over your concerns and questions as soon as you call us and get you set up with a scheduled appointment. Our team will arrive at the arranged time with all the needed resources, and will work closely with you all through the undertaking.
Whenever you are planning a project for Drain Cleaning in Beulah, MI, you'll find good reasons to work with Drain Cleaning Guys. We have the best customer satisfaction scores, the very best quality resources, and the most effective and efficient cash saving practices. We've got the experience that you need to satisfy all of your goals and objectives. When you need Drain Cleaning in Beulah, get in touch with Drain Cleaning Guys by dialing 800-964-5990, and we'll be beyond glad to help.

industry_corpus2: Real Estate & Construction


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When you think of world-class architecture, you probably think of New York City, London, maybe Shanghai or Dubai in the past few years. What you may not realize is that our very own city of Toronto is home to some of the most beautiful and interesting architecture that's been built in the past decade or so... and is also home to some of the most innovative architects.
Here, we profile three of the best in the city: superkül, Hariri Pontarini and Altius. They've worked on projects of all sizes, from luxe single-family homes to important landmark structures all over the world. And they're all pushing the boundaries of what architecture can do, what it means, and how structures can integrate into the world around them.
Founded inToronto in 2002 on a broad range of professional experience in Canada and abroad, superkül is recognized as a leading Canadian design practice. Our commitment to design excellence, pragmatism, and sustainability has resulted in numerous architecture and design awards and the publication of our work locally, nationally and internationally.
superkül is one of the busiest firms working in Southern Ontario today, creating modern structures that transform ordinary and legacy sites into, well, cool spaces. They're the masterminds behind the new 99 Sudbury, home to a hip new event space and one of Toronto's best seasonal restaurants. They also created the Linguistics Department facilities in the University ofToronto's Sidney Smith Hall along with several light-drenched, sleek residential builds.
Like superkul, Altius Architecture is at the forefront of new-modern design inToronto and the surrounding area. They call their style "a complete, holistic and collaborative approach to architecture", with a huge emphasis on sustainability, natural materials and green building. If you've ever driven up north for a weekend or a holiday, you may have encountered one of their stunning cottages, each of which is built both to incorporate and to stand out from the surrounding woodland or waterfront - and to let in every possible bit of light.
With laurels like the 2013 Ontario Residential Wood Design Award, Altius is an exceptional choice for those looking to build or renovate in tune with their surroundings.
Finally, Hariri Pontarini is the firm of choice for those who want to build big but also build smart. They are perhaps the most experimental and internationally acclaimed of the three, with their Baha'i temple inSantiago,Chile that resembles a paper lantern lit from within. They've also designed some ofToronto's most incredible homes in Forest Hill, the Bridle Path and other luxury enclaves. And if you've admired the new building at One Bloor East downtown? That's them, too.


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« A Passion For Collecting !
Kaminski Auctions and Tim Hopkins Catering teamed up to sponsor the Boston Lobsters 2015 KIck Off Party and Charity Auction at the Kaminski Auctions gallery in Beverly, Massachusetts. The gallery looked beautiful with flowers, Boston Lobster decorations and delicious hors d’oeuvres by Tim Hopkins !
Attended by tennis enthusiasts of the North Shore,Boston Lobster patrons, invited guests and most importantly tennis legend Billie Jean King.
Billie Jean King is an American former World No. 1 professional tennis player who won 39 Grand Slam titles. She is the the co-founder of Mylan World TeamTennis, the league of the Boston Lobsters and founder of the Billie Jean King Leadership Initiative.
A champion for social change and equality, she was named one of the “100 Most Important Americans of the 20th Century” by Life Magazine. In 2009, she was awarded the Presidential Medal of Freedom by President Obama, the nation’s highest civilian honor.
Auctioneer Frank Kaminski conducted the live auction of a Patriots football signed by Tom Brady, Tickets to Taylor Swift and tickets to the US Open in Billie Jean’s private box. The live auction was accompanied by an array of silent auction items.
The 2015 Boston Lobsters will be coached by Jan-Michael Gambill. This year the team will include 2011 French Open mixed doubles champion Scott Lipsky, and Spaniard, Arantxa Parra Santonja, along with a pair of young, up and coming Americans, 2012 NCAA doubles champion Chase Buchanan, and Irina Falconi, who recently made an inspired run to the 3rd round of the French Open.
Tennis Hall of Fame great Avis Murray and Mrs. Bonnie Covington with the Boston Lobster mascot !
The most exciting addition will be the 2014 Wimbledon finalist Eugenie Bouchard who will play the final 3 matches of the season, including a home match on July 27.
Kaminski Auctions and Timothy S.Hopkins Catering are proud to be sponsors and wish the Boston Lobsters a successful 2015 Season!

industry_corpus2: Sports


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You can receive an additional 15% Off any products in this category that you purchase. You may use this coupon more than once for subsequent orders until this ends.
Also, your Newsletter VIP (5%) and Super VIP (up to 5%) will stack on top of this code.


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The holidays are a busy time, especially for nonprofit organizations trying to make the season a little brighter for everyone. Give a gift this holiday season that is truly priceless by contributing your time to a nonprofit near you.
From donating items, to sorting them, to delivering them to families in need — or any other type of volunteering outlined in this year's guide — your time this holiday season is invaluable. To view or download the Holiday Giving and Volunteering Guide, visit United Way of the Greater Seacoast online at www.uwgs.org.
No matter what time of year, local food pantries need help. Download United Way's Guide to Area Food Pantries and Soup Kitchens from www.uwgs.org to locate services, donate food items, or volunteer to help. Because so many food pantries are small operations run by just a few dedicated volunteers and do not have Web sites or e-mail contacts, this guide helps people find out the best way to contact the organization prior to delivering donations to check on specific guidelines, needs and storage space.
The easy-to-use guide is organized by town and includes program days and times in addition to contact information.


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The UFC heavyweight champ, like most of the MMA world, isn't taking the idea seriously.
On Monday’s episode of Ariel Helwani’s MMA Show, UFC heavyweight champ Daniel Cormier weighed in on the idea of a boxing match between UFC lightweight champ Khabib Nurmagomedov and retired, undefeated boxing legend Floyd Mayweather, Jr.
In case you’re not up to speed, just over two weeks ago, Nurmagomedov tapped out Conor McGregor at UFC 229, defending his UFC lightweight championship belt. The athletes and their camps kept up the fighting after the official match was over. Just this week, Khabib called out Mayweather in a video that seemed like a lighthearted joke. Oh, and Mayweather answered. Still, Khabib doesn’t seem to be taking the idea seriously, and neither does the MMA world. And Cormier is no exception.
Cormier also joked that Nurmagomedov would probably resort to what he does best if Mayweather dominates in the boxing ring.
“Khabib’s gonna start wrestling in the boxing ring,” Cormier joked. “He's gonna get beat so bad, he’s gonna start wrestling.” But after Nurmagomedov's display after UFC 229, we wouldn’t put it past him to start wrestling pretty much anywhere.
Whether or not Nurmagomedov and Mayweather keep up their back-and-forth, Cormier will attempt to defend his heavyweight championship belt against Derrick Lewis at UFC 230 on November 3.
Check out the rest of his interview with Helwani below for more on the UFC 229 chaos, his headlining fight at UFC 230, and his potential fights before retirement.


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It might be early days for an observation like this (for me anyway); I started uploading to IS early in February and make what I thought was good progress. I didn't bother with any other agencies except a few uploads to DT. Sales at IS improved very micely and by the middle of March I was pleased with overall progress. Then I decided to join SS. Sales at SS took off sharply and I was mesmerised by the immediate positive result.
However my sales at IS peaked in exactly the same week that I joined SS. Over the past four weeks the trend at IS has been down, but still very positive sales at SS.
Of course Easter is in the middle, perhaps wiping two weeks of proper statistics, but I jave a sneaking suspicion that somehow my sales at SS have damaged my progress at IS.
Perhaps I'm wrong and its all just coincidence.
Anyone else have any thoughts on this from their own experiences?
I haven't found this to be a problem. I use the same nickname at all the sites so buyers can easily find me if they are looking for my images. This also lets them see that I have other images that they haven't seen at one or more of the other sites.
I somehow don't see many buyers taking the time to shop around. The difference in price is usually too minimal and time is money.
Just a coincidence, especially when looking at SS. SS is subscription so the one off buyers wont go there and a SS person who has a subscription probably wont buy else where.
You might loss a bit between the one off sites, but my guess is that very few price shop (look for the same image at a cheaper price) so what you are actually doing in increasing your odds since your photo will rank differently at different sites.
It has been discussed before, many veteran says it does not, it merely gives you greater exposure, even Laurin Rinder says it does not.
-> The advise is always dont go Exclusive with any stock sites and dont put all your eggs in one basket.
-> Its ebb and flow. istock is not doing too well for me this month. I did better in Jan and Feb 07. Wish it will pick up. istock generally is good but the downloads goes up and down. They keep changing the alogrithm every few weeks or so. I hope they dont keep this one. All the flames are in the first few pages.
can i submit same image to multiple agencies?
Upload a picture to multiple agencies in less than 2 minutes. For free!


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Martin Nievera – Martin Ramon Razon Nievera (born February 5, 1962, Manila, Philippines) is a Filipino singer, songwriter, and actor. He is one of the main hosts of musical variety show ASAP on ABS-CBN.
of The X Factor Philippines, which aired on ABS-CBN by the 2nd quarter of 2012.
Nievera was born on February 5, 1962, in Manila, Philippines to Roberto Nievera and Conchita Razon. He has a twin sister, Vicky. Nievera spent most of his childhood in Hawaii with his mother and father, as his father sang for the group Society of Seven. The Nievera family also took up residence in the Bay Area in California for a short time in the late ’70s. He graduated from Clayton Valley High School (Concord, California) in 1980.
Inspired by his father, Nievera returned to the Philippines in 1980 to begin his own singing career and by June 1980 he released his first LP, Martin…Take One and on 1994 Martin Nievera released Be my lady. Nievera began co-hosting the TV variety show Penthouse Live! with Pops Fernandez, who would later become his wife.
Nievera’s second LP was 1984’s The Best Gift. In 1987, Penthouse Live! was changed to Martin and Pops Twogether, in celebration of their marriage. His recording Forever led to two sequels, Forever Forever and Return to Forever. As an actor, Nievera has appeared in eleven movies and seven television series and specials. Nievera’s film credits include dramas, romance, science fiction, comedy and action.
He appeared with Hawaii’s Society of Seven and Lani Misalucha at the Flamingo Las Vegas from February 13 through April 13, 2008. He performed a pre-Valentine/post-birthday concert with Pops Fernandez titled “Missing You” on February 6, 2009, at the Smart Araneta Coliseum. He co-hosts the weekly music show called ASAP XV.
In July 2010, Nievera’s album, As Always was released.
In May 2011, his album, Himig Ng Damdamin was launched and contains all of his covers.
In May 2012, Martin’s new album was launched.


text: Welcome to 8tracks radio: free music streaming for any time, place, or mood. tagged with rock, stoner rock, and rock and roll. You can also download one of our free apps to enjoy internet radio on your favorite device.


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Slot.it / Policar have announced that the first livery of the Toyota GT86 will be available in September.
models of another Japanese brand which races in the same series in Japan is following close behind.
tyres for a smooth ride. They're the models that will also be featured inside the POLICAR boxed sets.
The cars can be easily converted to digital racing with our digital in-car ICs.
• Chassis: rather than the usual Policar/Slot.it chassis, we've opted for a simpler, single piece solution.
will not have a traction magnets, since Policar tracks will feature adjustable power supply and good mechanical grip.
combination on all other POLICAR models.
• Lights: front and rear lights will be standard on all these models.
• Upgrades: most Slot.it high performance racing axles, crowns, tyres and wheels may be used.
units will be available from our Shapeways web printing service.
Figured it would only be a matter of time before that car was available as a slot car. Pretty good move as a lot of people who own a full scale one will want to buy one. And there are plenty of them around.
I hope that they will produce also the GT4 version that is competing in the British GT championship this year.
What is that big board on the chassis? Just for the lights?
I find it funny that Slot it are making cars the way Scalextric have been for years. Respect.
On a serious note, not that slot.it is in the track business they will start selling slot car sets.
To keep the final price low, they need to have "home" version cars.
They will sell a separate chassis for allowing tuning.
I think it is the right move....as I collect cars I would not mind just to have the home version of most of their group C and DTM cars.
The one piece chassis and all plastic wheels is simply a price-point factor for entering the "toys" market with sets and spare cars.
They are in fact using some of their own mechanical parts which are still a better quality/system than most products sold into the same home market. So it seems to be a winning combo.
- I hadn't thought about the saving for collectors Gio - that's a useful point.
And for the record: - the prototype drove very well on regular Ninco track without magnet a year back when I was in Reggio, and they have made improvements since then for the cars you may have seen on video at Nurnberg - and to the track system over stock Ninco.
The last breed of scalex car (in line, standard wheels, and tray interior) are pretty good out of the box without magnets.
This slot.it release is following the came concept with some improvements: push-on plastic wheels and removable front axle (a la Carrera).
Unfortunately, this specific version of the toyota does not fit any class that we have at the moment.

industry_corpus2: Automobiles


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Hello and Welcome to Alchemy-Digitalmedia.co.uk – where our goal is to provide you with the most important tips and details that you should know about doing digital and web marketing yourself, or how to judge the work produced by those you’ve hired to do the work.
It is a sorry thing to say that web marketing businesses are amongst some of the least trustworthy, which means that for those who are paying for the services these businesses provide, it is also one of the most risky. Not only do you risk wasting your money with ineffectual services, you are also in danger of damaging your internet presence by, for instance, a google penalty. Knowledge is power, and having knowledge of website marketing is definitely an example of where this is the case; helping you to avoid worst-case scenarios just like this. Thankfully, finding our website is the first step into acquiring the knowledge you need about SEO, social marketing, content marketing, link building, reputation management, web design and development and a lot more.


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Who else wants to totally rock this shirt?
I am going to talk about the River Styx, the river you only see in Greek Mythology if you are dead and your loved ones remembered to put a coin in your mouth or on your eyes for the ferryman’s fee.
The river was named after the goddess Styx, who personified hatred and was an ally of Zeus in the Titan wars. Styx had many children who served under Zeus. She lived in a grotto above the river bearing her name in the underworld.
When a god or goddess took an oath, Iris would fly to the underworld and retrieve a cup of water from the river. The vow was made “By the River Styx” as the oath giver poured out the water from the cup. This vow was seen as binding.
The River Styx separated the world of the dead from the world of the living. When a soul made its way down to the river, it was transported into the underworld by Charon, the ferryman.
The Styx was not the only river of the underworld, but it is the most famous. In Dante’s Inferno, it is the river of the fifth circle of hell. This circle was reserved for people guilty of wrath, anger, and sulliness.
In Turning Creek, Petra is fond of the exclamations “Styx and fire.” Both Petra and Marina are known to say “hells” and “Styx.” All of these sayings reflect Virgil’s version of the underworld with its many levels.
The Remnants, like the real Greek myths, make binding vows “By the River Styx” though they do not dump out water from the river when they do so.

industry_corpus2: Literature & Emotions


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Magic Park Verden whisks visitors away to the realm of magicians, sorcerers and circus performers.
If you take a 30-minute walk through the fairytale forest, you'll discover life-sized, moving scenes from children's stories – simply enchanting!
Have you ever stroked a llama? At our petting zoo, you can get up close to all the animals.
There are also merry-go-rounds, trampolines and more – fun is as good as guaranteed!
Magic Park Verden is a leisure park, magic show, petting zoo and fairytale forest rolled into one and has become a hugely popular attraction for all the family.


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Glenside Care Home is a large residence set in its own grounds on the outskirts of Northampton and close to all amenities.
We care for people over the age of 40 with all types of dementia and mental health issues.
We want to provide the people in our care with a “home from home” experience and our care is all about “focusing on the person”.
We provide care by the day, on a short term basis and on a long term basis. We like to keep families and friends fully informed about the care being provided and encourage them to talk to us and ask questions when they visit.


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Shipping A Car To or From Kalispell, MT | A-1 Auto Transport, Inc.
Home to nearly 21,000 people, Kalispell is the right at the entryway to Glacier National Park and is a popular tourist destination due to the spectacular scenery, lakefront property and recreation available in the area. There are quite a few music and art shows in the downtown area, especially during the spring and summer. Snow skiing is popular in the wintertime and camping, hiking, fishing, and hunting are easily accessed at any time of the year.
You can learn more about Kalispell by checking out the official city website. The website has information for local job postings, electricity and water, the city council, and city departments.
Will it cost to get a quote?
Most companies offer free quotes for service but there are some that will charge to give a quote. Before proceeding with a quote you need to make sure it is free and will not be added onto the transport bill if you choose to hire the company.
What type of insurance coverage do you offer?
All companies that transport motor vehicles are required by law to provide insurance coverage for the vehicles they transport. If you have a very expensive luxury or collectible car, you may need to try to upgrade the coverage amount that the transporter offers as many companies will only offer the minimum coverage available. Some companies will allow you to upgrade for a higher cost. You may also want to check with your private carrier or a different company to add a private shipping policy to make sure the vehicle has adequate coverage.
How will the car be transported?
Most automobile transporters have open air carriers, but not all will have enclosed carriers. For the transport of classic, exotic and other collectible vehicles, you should ask the company if they have access to enclosed carriers as they are the safest way to ship an extremely valuable or delicate car. You will also want to see if the same driver that picks the vehicle up will be the same on that delivers. Many companies partner with or sub-contract their auto transport out to other carriers when they are unable to drive into the areas necessary to deliver a vehicle. When possible, it is best to use a company that offers one-truck delivery so you can stay in contact with the same driver the entire time and will know who is in possession of your car.
Reddaway has been in business since 1919 and they offer reliable, high-quality automobile transport to states in the western portion of the United States. They are an award winning company and have earned the Quest for Quality award given by Logistics Magazine for nearly 20 years. Auto transport is available to customer tracking via online tracking services. All transport is fully licensed, insured and bonded.
Dynamic Auto Transport is a used car dealer that also does auto transport to and from the Kalispell area of Montana. All transport is fully licensed, insured and bonded and they offer fast pickup and delivery as well as reasonable rates for services.


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It was proposed to use the 2H-labeled hydrolysate of RuMP facultative methylotroph Brevibacterium methylicum, obtained from deuterated salt medium dM9 as a substrate for the growth of inosine producing bacterium Bacillus subtilis. The growth of the bacterim was performed via glucose convertion on specially developed medium dHM with 78.5% (m/m) 2H2O and supplimented with 2.5% (m/m) of 2H-labeled methylotrophic hydrolysate. To evaluate the level of deuterium enrichment FAB MS technique was used after the isolation of 2H-labeled inosine. 2H-labeled inosine obtained from dHM medium represented a mixture of molecular species containing various number of included deuterium atoms with different contribution to the enrichment. The level of enrichmet calculated by the presence of most abandant peak of the molecular ion in cluster ((M+H)+ at m/z 274) was estimated as five deuterium atoms, from which three are attributed to ribose and two to hypoxantine.
Nucleosides labeled with deuterium (2H) and other stable isotopes are becoming an indispensable tool for biomedical diagnostic and the investigation of various aspects of the metabolism [1, 2]. Thus inosine which is known as an important intermediate in the synthesis of inosine monophosphate (IMP) is in the focal point of clinical interest in medical diagnostic of heart deceases and in certain medical cases [3, 4].
There are several approaches reported for the preparation of 2H- nucleosides. Chemical synthesis are usually tedious and inefficient. Only by employing mutant forms of bacteria, which can produce a large quantities of the nucleosides when growing of an organism on media containing deuterated substrates, the desired biochemicals can be obtained both with high yields and enrichments. On the microbial production of inosine, there have been many studies so far [5-7]. .
For instance, a certain adenine, histidine and tyrosine auxotrophic mutants derived from Bacillus subtilis have been found to have a remarkable ability to produce a large amount of inosine in the growth medium, and at the present it may be produced on an industrial scale.
The major disadvantage of production of 2H-nuclesides is difficulty in obtaining the appropriate deuterated growth substrates. One approach to solve this problem is to use the extracts obtained from microorganisms growing on minimal media with 99,9 at.% 2H2O far . Thus, we recently described a facultative methylotrophic bacterium Brevibacterium methylicum, which seems to be an an ideal source for the preparation of uniformelly labeled growth substrates on the basis of its 2H-biomass prepared from 2H2O and [U -2H]MetOH [9, 10]. In this article, we demonstrate the possibility of using the hydrolysates of 2H-labeled biomass of this bacterium as substrates for growing the inosine producing mutant B. subtillis.
2H2O (99.9 at.% 2H) was obtained from Russian Scientific Enterprises, Sanct Petersburg and purified by distillation from alkaline permanganate. [U -2H]methanol (95.7 at.% 2H) was from Biophysic Center, Pushino. All other chemicals were of reagent grade.
To create a high isotopic content in growth medium, 2H2O with trade marked isotopic purity 99.9 at.% 2H, was used. However, the deuterium content of used 2H2O verified by NMR was found to be 97 at.% 2H. The water containing salts were several times preliminarily crystallyzed in pure 2H2O and dried in vacuum before using (the true content of deuterium in growth media after the autoclaving was less smaller on 8-10% then isotopic purity of an initial 2H2O.
Adenine, tyrosine and hystidine auxotroph mutant B. subtilis B -3157 capable to produce and accumulate 17 g/liter of inosine during the growth on protonated medium with glucose and yeast extract was employed. The strain was obtained from Russian State Scientific Center for Genetics and Selection of Industrial Microorganisms GNIIGENETIKA.
The methylotrophic bacterium B. methylicum # 5662 was grown on salt medium dM9 with 93.5% (m/m) 2H2O and 2% (m/m) [U -2H]MetOH in mass culture . Cells were pelleted by centrifugation (2000 g, 10 min), washed once with 2H2O and stored at -14 0C. Periodically, 10 g (wet weight) portions are thawed, suspended in 0.5 N 2HCl solution (in 2H2O) and autoclaved at 1200C for 30 min. After adjusting pH till 7.0-7.2 with potassium hydroxide, the hydrolysate was used as a mixure of 2H-labeled growth substrates for the growth of inosine producing strain.
The bacterial growth was carried out on FM medium (m/m.%): glucose 12; yeast extract 2.5; ammonium nitrate 3; magnium sulphate 2; chalk 2. The composition of dHM was as the same as FM except dHM was prepared from 2H2O and the hydrolysate of 2H-labeled methylotrophic biomass was added. The media were sterilized by autoclaving at 1200C for 30 min and cooled. Glucose was sterilized separetely in 2H2O solution, and after that added in growth medium. рН was adjusted till 6.5-6.7 with potassium hydroxide. The bacterium was grown in 250 ml Erlenmeyer flasks containing 20 ml of the medium at 32-34 0С and vigorously aerated on an orbital shaker. After 7 days the cells were pelleted by centrifugation (2000 g, 10 min). The supernatant was separated, lyophilized and used for the isolation of 2H-labeled inosine.
MetOH solution in H2O (50 v/v %, 20 ml) was added to a lyophilized growth medium. The mixture was allowed to - 4 0C and after 10 h the total protein was precipitated and removed by centrifugation (1200 g, 10 min). MetOH was evaporated under reduced pressure. The resulting mixture was dissolved in 2H2O (30 ml) and 5 g of activated carbon was added. After keeping for 24 h at -4 0C, the inosine, eluting with ammonia, was concentrated and twice recrystallized from MetOH (nd20 = 1.33). The purity of the product was judged by using controls of normal nucleosides, and running mixed TLC with graded amounts of the neighboring nucleosides.
During the growth inosine was separated by TLC on Silufol UV-254 plates with mobile phases: n -ButOH - AcOH - water (2:1:1, v/v) using pure commercial available inosine as a standard. The amount of inosine was determined for 10 ml aliquots of liquid growth medium by TLC. The sports were eluted by 0.1 N solution of HCl (10 ml). The absorbance of the eluates was measured at 249 nm and the content of inosine was determined using a standard curve.
The convertion of glucose was estimated enzymatically with glucoseoxydenase method .
Absorbance was measured with a spectrophotometer Beckman DU-6 (USA).
The analysis of protein hydrolisates was carried out using a Biotronic LC 50001 chromatograph (Germany), 230 x 3.2 mm, working pressure 50-60 atm, flow-rate 18.5 ml/h.
The levels of deuterium enrichment of amino acids were investigated with the aid of EI MS after derivatization to methyl esters of N-Dns-amino acids .
FAB MS was performed on Hitachi MBA spectrometer (Japan) on glyserol template at potential 5 кV and an ion current of 0.6-0.8 мА.
For biosynthesis of 2H- labeled inosine we employed bacterium Bacillus subtillis, which could produce and accumulate a conciderable amount of inosine exogeniously due to an altered nucleoside metabolism. This strain displayed the maximum productivity on FM medium, containing as a source of carbon and energy glucose (12 m/m.%), and as a source of growth factors and additional source of nitrogen the yeast extract. Since the small availability of commercial available 2H-labeled biomass prepared from yeast, it was necessary to find the more suitable microbial source, from which the 2H-labeled growth substrates could be obtained. For this purpose we employed the available RuMP facultative methylotroph Brevibacterium methylicum  with the content of the total protein and polycarbohydrates in biomass 53 and 10% respectively .
The content of amino acids in biomass of B. methylicum and the deuterium enrichment are shown in Table.
The content of amino acids in biomass of B. methylicum and the deuterium enrichment.
The hydrolysis of 2H-labeled biomass was performed in mild conditions via its autoclaving (30 min, 08 atm) in 0.5 N solution of 2HCl (in 2H2O). The data on the amino acid composition of hydrolysate and levels of the enrichment are shown in Fig. 2. The contents of tyrosine and histidine in hydrolysate were 1.82 and 3.72% and can ensure the polyauxotrophy of the inosine producing strain. Another important parameter is a high level of amino acid enrichment.
1). FM medium, prepared from ordinary protonated water and yeast extract.
2). dHM medium, prepared from 87.5% (v/v) 2H2O and 2.5% (m/m) of 2H-labeled methylotrophic hydrolisate, obtained accordingly from medium dМ9.
Curves, reflecting the growth dynamics (a), convercion of glucose (b) and production of inosine (c) are given in Fig. 1. A maximal level of inosine production on ordinary protonated medium was 17 g\liter. When growing on dHM medium the strain produced only 3.9 g/liter of inosine throughout the whole course of the growth. The low level of inosine production was correlated with a degree of glucose conversion in those conditions. 4m/m.% of non-assimilated glucose was detected in medium dHM after the growth, that proved that glucose is metabolized less effectivelly on medium dHM, that is probably a result of non-equvalent replacement of yeast extract by methylotrophic hydrolysate.
The absorption spectra of inosine isolated from medium dHM (a) are shown in Fig. 2 comparatively to the growth medium (b) and commertially available inosine (c). TLC of isolated inosine showed the presence of main spot with Rf=0.5 (inosine) and additional spot with Rf=0.75 (hypoxantine). The output of 2H-labeled inosine was 1 gram from 1 liter of growth medium.
The method of FAB MS was employed for the evaluation of inosine enrichment. The fragmentation pathways of inosine by FAB MS are shown in Fig. 3. Two main decomposition processes arised from the molecule: sugar (m/z 133) and hypoxantine (m/z 136) formation. The compounds with a smaller m/z ratio may further to be formed as a result of elitination of HCN and CO from hypoxantine. The level of deuterium enrichment could be evaluated from the FAB mass spectrum of 2H-labeled inosine shown in Fig. 3, b compared with the non-labeled inosine (a). The results, firmely established the labeling of inosine as heterogenious, juging by the presence of clasters of adduct peaks at the molecular ion MH+; the species of molecules with different numbers of deuterium atoms were visualised. The most abundant peak with (M+H)+ at m/z 274 (instead of m/z 269 for non-labeled compound) in the claster was registered by mass spectrometer as a peak with average m/z ratio, from whom the enrichment of inosine was calculated as five deuterium atoms. The presence of peak corresponding to the hypoxantine fragment [C5H4ON4]+ at m/z 138 (instead of m/z 136) and the peak of sugar fragment [C5H9O4]+ at m /z 136 (instead of m/z 133) proved that two deuterium atoms are located in hypoxantine, however, three of them are attributed to the ribose pattern.
Mainly two aspects of the enrichment of inosine were taken into account (scheme). First, because protons in С'1-С'5 positions of ribose pattern in inosine could be originated from glucose, we assumed, that the character of biosynthetic enrichment of deuterium in sugar pattern of inosine is determined mainly to the functioning of a number of processes of hexose monophosphate shunt of glucose assimilation. But since protonated glucose was added in growth medium, its contribution in the inosine enrichment was minimal. Nevertheless, the results suggested, that ribose contained three deuterium atoms that could not stemp from glucose. Three deuterium atoms probably stemp via some minor reactions of glucose biosynthesis. Secondly, the numerous exchange processes and intermolecular regrouping reactions, occurring with participation of 2H2O could also be resulted in specific labelling of inosine. Such accessible positions are occupied by the easily exchangeable hydrogen (deuterium) atoms both of hydroxylic- and imino groups of inosine. Two protons at C-H positions in inosine could be replaced by deuterium via assimilation of 2H-labeled hydrolysate. The enrichment of inosine was approximately the same as 2H2O content in growth medium (65.5-67.5%).
1. Munch-Petersen A., (1983) Metabolism of nucleotides, nucleosides, and nucleobases in microorganisms. Academic Press. Inc., New York. 105.
2. Wuthrich K. (1986) NMR of proteins and nucleic acids. New York: J. Wiley & Sons. 14.
3. Bloch A. (1975) Chemistry, biology, and clinical uses of nucleoside analogs. Academic Press, New York. 58.
4. Farber E., Shull H., McConomy J.M., and Castillo A.E. (1965) Biochem. Pharmacol. 14, 761.
5. V.I. Shvets, A.M. Yurkevich, O.V. Mosin, D.A. Skladnev. (1995) Karadeniz Journal of Medical Sciences. 8. No 4. P.231-232.
6. Ishii K., & Shiio I., (1972) Agric. Biol. Chem. 36, 1511-1522.
7. Matsui H., Sato K., Enei H., and Takinamy K., (1982) Agric. Biol. Chem. 46, 2347-2352.
8. Katz J. & Crespi H.L. (1972) Pure Appl. Chem. 32, 221-250.
9. Mosin O.V., Karnaukhova E.N., Pshenichnikova A.B., et al. (1993) Biotechnology (Russia). 9, 16-20.
10. Egorova T.A., Mosin O.V., Eremin S.V., Karnaukhova E.N., Zvonkova E. N., Shvets V.I. 91993) Biotechnology (Russia) 8, 21-25.

industry_corpus2: Biopharmaceuticals


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After tracking mostly on pace through the first two months of the year, Summit County’s real estate sales hit a downturn in March, leading to a noticeable dip in the county’s first-quarter figures, according to Slifer Smith & Frampton.
The High Country real estate giant tracks a wide variety of statistics associated with the local real estate market, and Summit saw a roughly 12 percent decline in both its number of real estate transactions and their combined value for the first three months of 2018 compared to the first quarter of 2017, according to the company’s most recent market report.
The most expensive sale of the month, a luxury home at 584 Water Dance Drive in Frisco, went for $2.3 million. It’s a four-bedroom, five-bathroom 4,400-square-foot house in Frisco’s prestigious Water Dance neighborhood. A single-family home in the Ski Home subdivision of Breckenridge, along with a couple condos and a vacant lot, also in Breckenridge, rounded out the five priciest sales of the month, according to the Summit County Assessor’s Office.
And March did outperform the two months leading up to it, January and February, but the month remained 32 percent behind the number of sales and 40 percent below their combined value compared to the record-setting March 2017.
For Slifer Smith & Frampton, the county’s first-quarter decline can be blamed on a lackluster March, but moreover, the declines indicate a lack of available listings is starting to slow the pace of local real estate sales.
As proof, the company cites other statistics, like the falling number of days homes spend on the market, rising prices per square foot or a narrowing gap between asking and closing prices.
“Residential properties are still commanding higher prices and moving quickly,” the company surmised, offering an assessment not unique among local real estate professionals.
According to another monthly report, this one prepared by Coldwell Banker Mountain Properties, Summit County’s average sale price for a home was $636,000 in March, up from $572,450 in March 2017.
Additionally, Coldwell’s monthly market snapshot noted that the average price per square foot has risen at the same time the average number of days a home spends on the market has fallen to just 12 days.
The numbers can vary depending on town, price points and even neighborhood, but the trends reflect that demand is exceeding supply.
In fact, with 521 active listings on April 10, the number remains at record lows, according to Land Title Guarantee Company of Summit County, which breaks down those listings into 345 for residential properties and 176 for vacant land.
Looking at where those properties are, 231 were in Breckenridge, 129 in Silverthorne, 87 in Keystone, 36 in Copper, 27 in Frisco and 11 in Dillon, according to Slifer Smith & Frampton.
The Summit County Assessor’s Office also recently released March’s sales of record with information on 139 local real estate transactions worth $86.4 million. Compare that to March 2017, when there were 176 sales for $122.8 million, and it shows just how far apart the same months in subsequent years were.
Going back even further, this March’s sales were mostly in line with the same month in 2016, when there were 150 transactions worth $83.1 million. However, March 2016’s stats were buoyed by a $9.25 million sale.
As far as the luxury housing market goes, defined as housing sales at or over $1 million, LIV Sotheby’s International Reality, another local real estate broker, has also noticed a sharp decline in the number of transactions and a smaller reduction in their combined value this March.
However, that was coupled with a dramatic spike in the number of luxury houses coming on the market, with 42 new listings in March against 15 in February and 29 in March 2017.
42 Snowflake Drive Unit 505, Breckenridge for $1.75 million.
Vacant lot at 256 Timber Trail Road, Breckenridge for $1.75 million.


text: Your home isn't standard and your insurance policy shouldn't be either. You need specialized coverage that will take care of the things that matter to you. Foremost is flexible and understands your needs. We are happy to offer coverage choices for all different types of homes and homeowners. Lucky for you, J I Medina Investment's Insurance Agents can help you choose the right Foremost policy for your home, so you can relax while someone else takes care of the paperwork!


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What makes one website rank higher than another? This all depends on how the website is optimized for the search engines. If your website is not in the rank that you desire, it is time for you to learn the techniques of search engine optimization. This article contains some tips to get you started.
One of the most important aspects of web design and SEO services is simply staying dedicated to the process. You must be vigilant in keeping up to date with new tactics as search engines are known to change their tactics regularly. Also, if you don’t regularly modify your site, it will become stagnant and drop in the rankings.
Avoid using Flash content to help with SEO because it won’t. While it looks great and can be impressive, you are not allowed to link to single pages in a Flash site. For the best results, don’t rely completely on Flash. If you want to use it, do so sparingly.
To get the best SEO ranking, it’s important to write quality copy. Excellent copywriting is at the core of search engine optimization. It typically generates more visitors and attracts more inbound linking. Plus, the search engines, especially Google, have ways of determining how well a story is written and how useful it is, both of which are weighed in search engine ranking.
Optimizing your website is not that difficult, once you learn what the search engines like to see. Learn all that you can and put together a plan of action. Monitor your website for any positive movements in rank. If you are proactive and diligent in optimizing your website, before long, you will see positive results. For more information on web design and SEO services, contact ViralWeb.net.


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Sell your house to one of the respectful and trustable real estate company in Philadelphia. We understand your needs and provide you efficient service immediately without extra charges or commission. While buying your home, all the procedures we follow will be completely authorized and systematic. We are always there to help about how to sell your home fast.
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Energy and Environment - Specializing in energy efficient projects for Commercial, Industrial and Military customers.
Environment Georgia - Environmental advocacy organization,takes independent research& tough-minded advocacy to win concrete results for our environment.
EPD - Designed to provide easy-to-find information about our efforts to protect and manage Georgia's air, water and land resources.
GEFA - Administers a wide variety of programs that provide financial assistance& other support services to improve Georgia’s environment.
Georgia Conservancy - A catalyst for the stewardship of our natural environment through education, principled advocacy, and more.
Georgia Department of Natural Resources - Mission to protect and preserve Georgia's natural, historic, and cultural resources.
Georgia PIRG - Mission to deliver persistent, result-oriented public interest activism that protects our environment.
Georgia Solar Energy Association - Promotes the economic and environmental benefits of solar energy through education, advocacy and industry support.
SELC - Protecting the south's air, water, wild places, and communities.
Southface online - Helping in finding easy ways to save energy, conserve water and preserve the environment.

industry_corpus2: Power & Energy


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We keep consuming greater and greater quantities of sugar, which is why understanding its biochemical mechanisms is so important: That knowledge can help us kick the habit.
August 25, 2014, 6:29 p.m.
Our sugar consumption is, frankly, out of control. On average, Americans keep eating more of the sweet stuff every year, we crave it (terribly) when we cut back, and even as health professionals have told us for years that it's something we are eating (and drinking) too much of, we keep shoveling it in, with the invariable result that more of us are overweight and obese than ever before, and even worse, kids are following the lead of adults (to the point where parents can't even tell when their kids have a weight problem anymore).
The World Health Organization suggests consuming 40-50 pounds of sugar a year, based on a 2,000-2,500 calorie-a-day diet. But we are up from 122 pounds a year in 1970 to 150-170 pounds a year in the late 2000s. The average (meaning some people are eating more) is three times what it should be. And compare that to the 7-8 pounds a year we ate in the 1700s (though obviously wealthy people had access to much more than that, while poor people probably got none), and in just a few hundred years of human history, well, Houston, we've got a problem. If we keep going at the rate we have been, our diets will be 100 percent sugar by 2606.
Of course that last stat is a bit silly, but taking all the information into account, it begs the question: Are we a nation of sugar addicts? If anything but slight decreases seem well-nigh impossible, if, despite wreaking havoc on our health (and teeth!), we still can't seem to get the sugar-plum fairy off our backs, maybe we should just admit that the sweet stuff is (at least mildly) addictive — and do something about it.
The chorus of anti-sugar activists is growing and getting louder, and they are suggesting that we might want to start treating sugar as a drug, just like alcohol and tobacco — and we may even want to regulate it as such.
Dr. Robert Lustig, a medical expert at the University of California, San Francisco, has written several papers, including The Toxic Truth About Sugar and Fructose: It's 'alcohol without the buzz' and he lays it out in no uncertain terms: "The definition of addicted is that you know it's bad for you and you can't stop anyway, like heroin, cocaine, alcohol, and nicotine. You know it's bad for you. You know it will kill you. But you can't stop anyway, because the biochemical drive to consume is greater than any cognitive ability to restrain oneself. There are two phenomena attached to addiction: one's called tolerance, the other is withdrawal. It turns out sugar does both of those as well. If a substance is abused and addictive and it contributes to societal problems, that's criteria for regulation," Lustig told Vox.com.
Lustig obviously feels strongly about the subject, and while some of his critics say his demonization of sugar is overblown, people also pooh-poohed the idea of cigarettes as problematic too. With sugar tied to every chronic metabolic disease, says Lustig, including obesity and diabetes, of course, but also fatty liver disease, heart disease, lipid problems, and even cancer and dementia, it's time to act.
But he's not suggesting we ban sugar. (Mostly because we know that doesn't work.) Lustig says, "... we're [not] going to have ice-cream sodas speakeasies or anything like that. We tried banning alcohol, and look what happened; it was a complete and utter disaster. So no one is talking about getting rid of it, but in order to solve this public health debacle we have to reduce consumption. The only way to do that for an addictive substance is to reduce availability, and the only way to reduce availability is taxation or restriction of access or banning. Forget banning; that's out. That leaves taxation and restriction of access — well, that's regulation."
So for all those people who protested former NYC Mayor Michael Bloomberg's controversial giant soda ban (I supported it), because "people should make their own decisions about what they eat" look out: Because Lustig and other health advocates trying to keep health care costs down for all of us are trying to do something similar: use public policy to discourage unhealthy consumption of an addictive substance. And we know it will work: Just look at how few of your friends smoke cigarettes anymore.
We keep consuming greater quantities of sugar. Understanding its biochemical mechanisms can help us kick the habit.


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How Effective is Pertussis Vaccine?
Most public health officials maintain that when pertussis vaccine is used on a widespread basis in a population, it appears to lessen the overall incidence of the disease and that vaccinated children have less severe cases of pertussis whooping cough.
1 Pulendran B, Ahmed R. Immunological mechanisms of vaccination. Nat Immunol 2011; 12(6): 509-517.
2 Thakur A, Pedersen LE, Jungersen G. Immune markers and correlates of protection for vaccine induced immune responses. Vaccine 2012; 30(33): 4907-4920.
3 Flaxman A, Ewer KJ. Methods for Measuring T-Cell Memory to Vaccination: From Mouse to Man. Vaccines 2018; 6(43).
4 Fine PEM, Clarkson JA. The Recurrence of Whooping Cough: Possible Implications for Assessment of Vaccine Efficacy. Lancet 1982; 1(8273): 666-669.
5 Trollfors B. Bordetella Pertussis Whole Cell Vaccines: Efficacy and Toxicity. Acta Pediatrica Scandinavica. 1984 73: 917-923.
6Transcript (partial) of May 12, 1986 ACIP Meeting discussion of DPT risks and failures. Pgs. 34-37. NVIC.org.
7 Preston NW, Stanbridge TN. Efficacy of Pertussis Vaccines: A Brighter Horizon. Brit Med J 1972; 3:448-451.
8 Broome CV, Preblud SR, Bruner B et al. Epidemiology of pertussis, Atlanta, 1977. J Pediatr 1981; 98(3): 362-267.
9 Fine PE, Clarkson JA. Reflections on the efficacy of pertussis vaccines. Rev Infect Dis 1987; 9(5): 866-883.
10 Greco D, Salmaso S, Mastrantonio P et al. A Controlled Trial of Two Acellular Vaccines and One Whole-Cell Vaccine Against Pertussis. N Engl J Med 1996; 334(6): 341-348.
11 Schmitt HJ, Schuind A, Knuf M et al. Acellullar Pertussis Vaccines: The Rationale for an Efficacy Trial in Germany. J Infect Dis 1996; 174(Suppl 3): S287-S290.
12 Lavine J, Bjornstad O, et al. Short-lived immunity against pertussis, age-specific routes of transmission, and the utility of a teenage booster vaccine. Vaccine 2012; 30(3): 544-551.
15 Misegades LK, Winter K, Harriman K et al. Association of Childhood Pertussis With Receipt of 5 Doses of Pertussis Vaccine by Time Since Last Vaccine Dose, California, 2010 JAMA 2012; 308(20): 2126-2132.
16 Matthias J, Pritchard S, Martin SW et al. Sustained Transmission of Pertussis in Vaccinated, 1–5-Year-Old Children in a Preschool, Florida, USA. Emerg Infect Dis Jan. 15, 2016.
17 Klein NP, Bartless S, Fireman B, Baxter R. Waning Tdap Effectiveness in Adolescents. Pediatrics Feb. 3, 2016.
18 Gustafsson L, Hallander HO, Olin P et al. A Controlled Trial of a Two-Component Acellular, A Five-Component Acellular, and a Whole Cell Pertussis Vaccine. New Engl J Med 1996; 334(6): 349-355.
19 Greco D, Salmaso S, Mastrantonio P et al. A Controlled Trial of Two Acellular Vaccines and One Whole-Cell Vaccine Against Pertussis. N Engl J Med 1996; 334(6): 341-348.
20 Zhang L, Prietsch SOM et al. Acellular vaccines for preventing whooping cough in children (Review). The Cochrane Library 2014, Issue 9.
21 Bisgard KM, Rhodes P et al. Pertussis vaccine effectiveness among children 6 to 59 months of age in the United States, 1998-2001. Pediatrics. 2005 Aug;116(2):e285-94.
23 CDC. Prevention and Control of Influenza. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR July 28, 2006; 55(RR10): 1-42.
24 Wei SC, Tetti K, Cushing K et al. Effectiveness of Adolescent and Adult Tetanus Reduced-Dose Diphtheria and Acellular Pertussis Vaccine against Pertussis. Clin Infect Dis 2010; 51(3): 315-321.
26 Hinman A, Orenstein WA, Schuchat A. Vaccine Preventable Diseases, Immunization and MMWR 1961-2011.MMWR Oct. 7, 2011; 60(04): 49-57.
30 Bamberger ES, Srugo I. What is new in pertussis? Eur J Pediatr 2008; 167: 133-139.
31 Cherry JD. Why Do Pertussis Vaccines Fail? Pediatrics 2012; 129(5).
32 Zouari A, Smaoui H, Kechrid A. The diagnosis of pertussis: which method to choose? Crit Rev Microbiol 2012; 38(2): 111-121.
33 Van der Zee A, Schellekens JF, Mooi FR. Laboratory Diagnosis of Pertussis. Clin Microbiol Rev 2015; 28(4): 1005-1026.
34 Sutter RW, Cochi SL. Pertussis Hospitalizations and Mortality in the United States, 1985-1988: Evaluation of the Completeness of National Reporting. JAMA 1992; 267(3): 386-391.
36 Cherry JD. The Epidemiology of Pertussis: A Comparison of the Epidemiology of the Disease Pertussis With the Epidemiology of Bordetella pertussis Infection. Pediatrics 2005; 115(5).
37 Ward JI, Cherry JD, Chang S et al. Efficacy of an Acellular Pertussis Vaccine among Adolescents and Adults. N Eng J Med 2005; 353(15): 1555-1563.
38 Long SS, Lischner HW et al. Serologic evidence of subclinical pertussis in immunized children. Pediatr Infect Dis 1990; 9(10): 700-705.
39 He Q, Viljanen MK, Nikkari S et al. Outcomes of Bordetella pertussis Infection in Different Age Groups in an Immunized Population. J Infect Dis 1994; 170: 873-877.
40 Zhang Q, Yin Z, Shao LH et al. Prevalence of asymptomatic Bordetella pertussis and Bordetella parapertussis infections among school children in China as determined by pooled real-time PCR: a cross-sectional study. Scand J Infect Dis 2014; 46(4): 280-287.
41 Wendelboe AM, Van Rie A et al.Duration of immunity against pertussis after natural infection or vaccination. Pediatr Infect Dis J 2005; 24(Suppl 5): S58-S61.
43 Warfel JM, Zimmerman LI, Merkel TJ. Acellular pertussis vaccines protect against disease but fail to prevent infection and transmission in a nonhuman primate model. Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):787-92.
44 Hewlett EK, Burns DL Cotter PA et al. Pertussis Pathogenesis – What We Know and What We Don’t Know. J Infect Dis 2014; 209: 982-985.
45 Robbins JB, Schneerson R, Kubler-Kielb J et al. Toward a new vaccine for pertussis. PNAS 2014; 111(9): 3213-3216.
46 Riolo MA, Rohani.Combating pertussis resurgence: One booster vaccination schedule does not fit all. Proc Nat Acad Sci 2015; 112(5): E472-477.
47 De Celles MD, Magpantay FMG et al.The pertussis enigma: reconciling epidemiology, immunology and evolution. Proc R Soc B 2016; 283.
48 CDC. Pertussis (Whooping Cough) Cases by Year (1922-2014). Sept. 8, 2015.
49 Fine PEM, Clarkson JA. The Recurrence of Whooping Cough: Possible Implications for Assessment of Vaccine Efficacy. Lancet 1982; 1(8273): 666-669.
50 Marchant CD, Loughlin AM, Lett SM et al. Pertussis in Massachusetts, 1981-1991: incidence, serologic diagnosis, and vaccine effectiveness. J Infect Dis 1994; 169(6): 1297-1305.
51 Tanaka M, Vitek CR, Pascual B et al.Trends in Pertussis Among Infants in the United States, 1980-1999.JAMA 2003 Dec 10;290(22):2968-75..
52 Nelson JD. The changing epidemiology of pertussis in young infants. The role of adults as reservoirs of infection. Am J Dis Child 1978 132(4): 371-373.
53 Yih WK, Lett SM, desVignes FN et al. The increasing incidence of pertussis in Massachusetts adolescents and adults 1989-1998. J Infect Dis 2000; 182(5): 1409-1416.
54 Jenkinson D. Duration of effectiveness of pertussis vaccine: evidence form a 10 year community study. Brit Med J 1988; 296: 612-614.
55 Christie CDC, Marx ML, Colin D et al. The 1993 Epidemic of Pertussis in Cincinnati. N Engl J Med 1994; 331: 16-21.
56 DeSerres G, Boulianne N et al. Pertussis in Quebec: ongoing epidemic since the late 1980’s. Can Commun Dis Rep 1995; 21(5): 45-48.
57 CDC. Pertussis Outbreak – Vermont, 1996. MMWR Sept. 5, 1997; 46(35): 822-826.
58 Conley JM, Johnston BL. The role of the acellular pertussis vaccine and the demise of ‘Pertussis Pete.’ Can J Infect Dis 2001; 12(1).
59 Bouchez B, Guiso N. Bordetella pertussis, B. parapertussis, vaccines and cycles of whooping cough. FEMS Pathogens and Disease Aug. 4, 2015 (online).
60 CDC. Pertussis – United States, January 1992-June 1995. MMWR July 21, 1995; 44(28): 525-529.
61 Hinman A, Orenstein WA, Schuchat A. Vaccine Preventable Diseases, Immunization and MMWR 1961-2011. MMWR Oct. 7, 2011; 60(04): 49-57.
62 Mooi FR, van Oirschot H, Heuvelman K et al. Polymorphism in the Bordetella pertussis Virulance Factors P. 69/Pertactin and Pertussis Toxin in The Netherlands: Temporal Trends and Evidence for Vaccine-Driven Evolution. Infect Immun 1998; 66(2): 670-675.
63 Simondon F., Guiso N. Genetic evolution under vaccine pressure: the Bordetella pertussis model. Bull Soc Pathol Exot 2000; 93(3): 202-205.
64 De Melker HE, Schellekens JFP, Neppelenbroek SE et al. Reemergence of Pertussis in the Highly Vaccinated Population of the Netherlands: Observations on Surveillance Data. Emerg Infect Dis 2000; 6(4): 348-357.
65 Mooi FR, vanLoo IHM, King AJ . Adaptation of Bordetella pertussis to vaccination: A Cause for Its Reemergence? Emerg Infect Dis 2001; 7(3): 526-528.
66 Weber C, Boursaux-Eude C, Coralie G et al. Polymorphism of Bordetella pertussis Isolates Circulating for the Last 10 Years in France, Where a Single Effective Whole-Cell Vaccine Has Been Used for More than 30 Years. J Clin Microbiol 2001; 39(12): 4296-4403.
67 Bart MJ, van Gent M, van der Heide HGJ et al. Comparative genomics of prevaccination and modern Bordetella pertussis strains. BMC Genomics 2010; 11: 627.
68 Xu Y, Liu B et al. Whole-genome sequencing reveals the effect of vaccination on the evolution of Bordetella pertussis. Sci Rep 2015; 5: 12888.
69 Mooi FR, van Loo IHM, van Gent M et al. Bordetella pertussis Strains with Increased Toxin Production Associated with Pertussis Resurgence. Emerg Infect Dis 2009; 15(8): 1206-1213.
70 Kallonen T, He Q. Bordetella pertussis strain variation and evolution post vaccination. Expert Rev Vaccines 2009; 8(7): 863-875.
71 Mooi FR. Bordetella pertussis and vaccination: the persistence of a genetically monomorphic pathogen. Infect Genet Evol 2010; 10(1): 36-49.
72 Guiso N, Hegerle N. Other Bordetellas, lessons for and from pertussis vaccines. Expert Rev Vaccines 2014; 13(9): 1125-1133.
73 Bouchez V, Hegerle N, Strati F et al. New Data on Vaccine Antigen Deficient Bordetella pertussis Isolates. Vaccines (Basel) 2015; 3(3): 751-770.
74 Bart MJ, Harris SR et al. Global Population Structure and Evolution of Bordetella pertussis and Their Relationship with Vaccination. MBio 2014; 5(2).
77 He Q, Viljanen MK et al. Whooping cough caused by Bordetella pertussis and Bordetella parapertussis in an immunized population. JAMA. 1998 Aug 19;280(7):635-7.
78 Liese JG, Renner C et al. Clinical and epidemiological picture of B pertussis and B parapertussis infections after introduction of acellular pertussis vaccines. Arch Dis Child. 2003 Aug;88(8):684-7.
79 He Q, Viljanen MK et al. Whooping cough caused by Bordetella pertussis and Bordetella parapertussis in an immunized population. JAMA. 1998 Aug 19;280(7):635-7.


text:
Havana turned 7 today. After swimming lessons, we went to Havana’s favorite restaurant for birthday dinner: Pagliacci’s on Madison. She says it’s her favorite because “it has lots of windows” but I think it’s because of the cool make-your-own-flavored-Cokes machine.
Then we had cupcakes at home.
While leaving Pagliacci, we ran into Steve Wells, a guy we worked with at Microsoft who we haven’t seen in 15 years. Small city.
She’s growing up to be such a lovely young woman. Happy Birthday!

industry_corpus2: Hospitality & Catering


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“Chance always meets a prepared mind”, said Klaus Lehmann. He added that everything we experience is an expression of our own mind. He used the word “serendipity” for this.
Ceramics Born of the Spirit of Music and Nature.
Made from the reflexes, the possibilities, the experience of the fingers, of the hand, of the whole body.
Toubes’ work documents the world in motion – from the speach by Nele van Wieringen.
The glaze, the seihakuji glaze, reminiscent of a cloudless sky or the colour of a glacier, moves on the object, it melts and floats downwards until the artist cries halt by finishing the firing.


text: Booklet 7. A beautiful ceremony booklet with the idyllic picture of the couple as two children holding hands. To purchase either a sample booklet or sample cover please select your options below. This price includes P&P.


text:
Fine, this has taken too long! The years before we had a plan but a comment last year has ruined this plan. Usually we see who or what influenced our lives more than anything the year that ends and we write the reasoning naming the persona or the events of the year and last year it was the economic crisis that had changed our lives, dramatically I would say.
The name Barack Obama kept coming out all the time last year and still keeps coming this year but this time it was us who had our doubts. Not because Barack Obama has stopped to be the carrier of hope and we all give him plenty of time and excuse to succeed despite all the small or big setbacks. But then came December and the big flop, the UN Summit for the environment in Copenhagen to make at least me a bit sceptic about the future. Barack Obama decided to give a stand up to the environmental issues in favour of his health plan. Again even though everybody fully understands how valuable it is a health system in USA and in long term it might become a blueprint internationally it is still something internal and that Obama preferred to give that battle only it was a bit disappointed for the ones who are fully aware of what’s going on in the environment. What can you do with a perfect health system when thousands if not millions die because of the distraction we cause to earth. And in this case there is one more disappointing element; that the lobbies that Barack Obama was so much after during his campaign have won since they manage to make him chose.
The financial crisis is still here, actually worst than the year before and nobody really knows when it will end. The worst part is that when it will end what is going to leave behind and if the number of the neo-poor, unemployed, homeless will not create a new financial reality that will even include clashes and rebellions. You see the financial crisis has made the poor poorer but the same time also created a new reality for the rich making the rich richer and new profits this time more cynic and often cannibal literally making profits on dead bodies.
Hard times like that I often remember something Jean Paul Sartre said, that in hard times art, literature found a way to thrive; but Jean Paul Sartre was referring to the Nazi occupation in France when he was talking about hard times and even during that occupation there was something physical. Nowadays the crisis that comes to all the fields is eating the spirit and it is natural that art is beaten as well. Nowadays everything has become a constant fight to survival from the uncontrolled and unexpected. A bank faces financial problems in USA because of bad management and the milk goes more expensive in my neighbourhood in Finland and it looks impossible for the Finnish government to do something about it.
Bottom line is that whatever we say, whatever we hope, whatever message Barack Obama’s presents in the international scene has brought this last year we always end up in politics. If the experts were left to decide for the future of the environment things would have been different but even the scientists depend on political decisions. If the experts had been heard about the financial crisis perhaps this things would have never taken the gigantic dimensions it took but in the end it was a political decision, if Barack Obama was left to make what he wanted to do things would have been different already but political lobbies with political influences don’t let him and again it ends in politics and for the ones that follow art they know how much politics influence art the last decades; even the literature Nobel Prizes have a political edge. So what is left is politics.
And this is where my thought about the persona or the event of the year end. There is a politician in the international scene that mocks with his controversial attitude everything that he represents. It is the man who constantly reminds us how fragile our democracy is and the same time with his often over-dramatic moves makes us laugh. The man was hit from a mad man and most of us smiled when we saw the scenes on the news with him climbing on top of his car to show his bloody face. If you are Italian nowadays living abroad you always have to face the smile the man brings and the uncomfortable questions from everybody. If you are European you don’t know how to deal with this phenomenon coming from the Caesar’s land and literally everybody for Japan to Chile and South Africa to Alaska knows Mr. Silvio Berlusconi!
As I said before Silvio Berlusconi reminds us constantly how fragile democracy is but the same time he shows us how human and weak authority is, that there is no magic way that transforms human with passions and faults to super-humans when they become authority doesn’t matter how high this authority is. The man is a prove that power corrupts in every single sense and with his every single act. And the same time Silvio Berlusconi makes us laugh. He makes us laugh because in a very twisted way he is one of us and I suppose that’s the reason the Italian people vote him again and again giving him the power to stand there and feel god. The man is a painful joke but the same time he is fully representing the true face of politics and the ones who hold with their decision our future and the solution to things like the economic crisis or the environmental issues!
Vis a vis that Man born in Bethlehem the powerful politician residing in Rome by the name of Caesar Augustus looks like a puny instrument used by Providence to make it possible for a man to fulfill his mission and for that mission to then spread to a whole continent called Europe. Indeed there were two men in the year 0 and the greater of the two was not the politician but the non-politician. The one who affected history the most was the one who exemplified principle not based on political power. The cynics among us will continue pointing out of course that the same man, only thirty years later was condemned and put on a cross by the very same power that ordered the census, which proves that he was a loser. I would suggest that they are being clever by half; they are missing the other half of the picture: the conspiracy and audacity of hope, still ongoing.
Errata above: wield power, exemplified principles.
Attempts to refute the identification of justice (the order of human things) with power-politics, fail to convince those who are not Christian believers, as long as those appeals presuppose the veracity of Christian revelation and the divine foundation of the Catholic Church.
For, the Machiavellian may easily retort that the rise of Christianity is itself testimony of power-politics (cf. Nietzsche).
The problem at hand lies in the depreciation of politics testified by the Hedonist's identification of justice with power. But political life always presupposes/entails an END, whereas amorphous "power" does not. Man as "political animal" cannot be understood unless we take into primary consideration the ENDS for the sake of which he struggles. The "abstract" reduction of those ENDS to "Struggle" points straight to the infamous doctrine of the Will to Power. which volens nolens serves as "ontological" support for barbarism.
It would seem that the only rationally effective response to power-politics doctrines rests in the recovery of a pre-modern, classical understanding of "the Political" on account of which man's practical life is not yet abstracted from its NATURAL ENDS.

industry_corpus2: Politics & Administration


text:
Look, there are endless blog posts and articles out there that talk about query letter mistakes. If you’ve ever Googled for tips, you’re aware of all the heavy hitting highlights.
Do your research when querying agents.
Don’t get too wordy when describing your book.
Write a solid hook that gets the reader psyched.
Don’t BCC a hundred agents with DEAR AGENT because no literary agent has the name AGENT, and if that is their name, I guess they were born to be a literary agent.
You know them. So we’re not gonna recap.
But one trend I’ve been noticing lately is one I haven’t seen many people dish about, and I feel like it’s worth digging into. And it has to do with talking smack. Sometimes it’s about an author, or sometimes it gets a little broader… like talking down about an entire genre.
This… is not a good look.
There is a difference between well-written criticism and just saying “this book is bad and I’m better” in a query. A difference between wanting to do something new in a genre and saying “I hate modern fantasy novels they are all awful” in your pitch.
Talking Down on Your Genre or Category: It’s strange. I get a lot of query letters that talk trash about the genre or category the writer is hoping to publish in. “Sci-fi novels these days are bad because…” or “Young Adult books being published today aren’t good due to…” whatever the following insult is. Stress on the insult, because it is never legit criticism. Usually it’s about those books not being up to the standards of the querying writer, or they’re making claims that the books aren’t doing what that writer thinks they should be doing.
Not only does this make you seem bitter and salty (and not in a delicious sea salt dark chocolate sort of way), but it makes you seem out of touch with what’s being published. Telling me there hasn’t been a great fantasy novel published in the past few years, tells me you don’t read fantasy. Proclaiming that YA doesn’t take risks anymore, tells me you haven’t gone to your local bookstore in a long time.
Don’t talk down. Show us you are excited to write in this genre or category. Not that you’re here to belittle the work of people who came before you. You can explain how your work is unique and does something different without tearing your genre down.
Talking Down Other Books or Authors: I love comparative titles (I wrote a whole post about it here!), and discussing why readers of other books or consumers of other media (if you’re using video games, comics, movies as comps) will like your book. It shows you’re well read and know your audience.
Explaining why your book is better than another book, or why you’re superior to another author… not so much.
Remember, the book world is a community. I want to work with an author who is excited to be a part of it, not someone who is going to launch into their career talking smack about their peers before anything has even happened. And if a book has been widely considered to be bad, why compare your work to it anyway?
Also, what if that agent likes that author? That book? Don’t risk it.
Doing That Self-Deprecating Thing: And one more thing I see all too often, are writers who do this self-deprecating thing in their query letters.
Basically, talking down about themselves.
To be a writer and a creative is to be insecure. I get it. I write too, and I wrestle with that constantly. Your query letter though, isn’t the place to share it. You wouldn’t put “I really don’t think I’m that great” in a cover letter for a new job, right? Well, it shouldn’t go in your query.
Be confident. You’ve worked on this novel. You’ve poured months and maybe years into it, and now you are ready to see it go to the next level. Show that you are sure of your work. Your agent is going to have to be your champion. How are they supposed to champion something that you yourself have flat out told us you don’t believe in?
Show that you believe in your work. Don’t talk down about yourself or what you’ve written.
You can do this without talking smack about others.
And you can do this while believing in yourself.
This might be a good way to weed people out. What a strange thing to do. It’s one thing to think such-and-such a genre has gone down the tubes (I’ve certainly had those thoughts) but a query is not the place to share your rantings – a bar with other writers is.
While I do agree with your first two points, I not so certain about your third. It’s one thing for a writer to be confident in their work, but another thing to declare it the best thing you’ll ever read. What is wrong with showing a little humility and letting the book speak for itself?