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ANGPTL8/Betatrophin Does Not Control Pancreatic Beta Cell Expansion.
SUMMARY Recently, it was reported that angiopoietin-like protein 8 (ANGPTL8) was the long-sought “betatrophin” that could control pancreatic beta cell proliferation. However, studies of Angptl8?/? mice revealed profound reduction of triglyceride levels, but no abnormalities in glucose homeostasis. We now report that Angptl8?/? mice undergo entirely normal beta cell expansion in response to insulin resistance resulting from either a high-fat diet or from the administration of the insulin receptor antagonist S961. Furthermore, overexpression of ANGPTL8 in livers of mice doubles plasma triglyceride levels, but does not alter beta cell expansion nor glucose metabolism. These data indicate that ANGPTL8 does not play a role in controlling beta cell growth, nor can it be given to induce such expansion. The findings that plasma triglyceride levels are reduced by Angptl8 deletion and increased following ANGPTL8 overexpression support the possibility that inhibition of ANGPTL8 represents a therapeutic strategy for hypertriglyceridemia.
Circulating Angiopoietin-like Protein 8 Is Independently Associated With Fasting Plasma Glucose and Type 2 Diabetes Mellitus.
OBJECTIVE: Angiopoietin-like protein 8 (Angptl8) has recently been introduced as a novel adipokine/hepatokine that promotes pancreatic ß-cell proliferation and improves glucose tolerance in mouse models of insulin resistance. However, regulation of Angptl8 in human type 2 diabetes mellitus (T2DM) and renal dysfunction has not been determined.
RESEARCH DESIGN AND METHODS: Serum Angptl8 levels were quantified by ELISA in 62 patients with T2DM as compared with 58 nondiabetic subjects in vivo. Within both groups, about half of the patients were on chronic hemodialysis or had an estimated glomerular filtration rate above 50 mL/min/1.73 m2. Furthermore, we investigated the effect of insulin and differentiation on Angptl8mRNA expression in 3T3-L1 adipocytes in vitro.
RESULTS: Median [interquartile range] serum Angptl8 levels were higher in patients with T2DM (1.19 [0.37] μg/L) as compared with nondiabetic subjects (1.03 [0.47] μg/L) (P = .005). Furthermore, the adipokine/hepatokine was significantly higher in women (1.21 [0.47] μg/L) as compared with men (1.05 [0.44] μg/L]) (P = .013). In multivariate analysis, fasting glucose and T2DM but not renal function remained independent and positive predictors of circulating Angptl8 even after adjustment for markers of obesity, lipid status, and inflammation (P < .05). Furthermore, Angptl8 mRNA expression was induced by insulin and during adipogenesis in 3T3-L1 adipocytes in vitro. Conclusions: Circulating Angptl8 is positively and independently associated with T2DM and fasting glucose in vivo. Furthermore, Angptl8 mRNA expression is induced by insulin and during adipogenesis in 3T3-L1 adipocytes in vitro.
Elevated circulating lipasin/betatrophin in human type 2 diabetes and obesity.
Lipasin (also known as C19ORF80, RIFL, ANGPTL8 and betatrophin) is a newly discovered circulating factor that regulates lipid metabolism and promotes pancreatic ?-cell proliferation. Whether circulating levels of lipasin in humans are altered in a) type 2 diabetes; b) obesity and c) the postprandial state, however, is unknown. The current study aimed to compare serum lipasin levels in those who were a) non-diabetic (N = 15) or diabetic (BMI- and age-matched; N = 14); b) lean or obese (N = 53 totally) and c) fasting and 2 hours following a defined meal (N = 12). Serum lipasin levels were determined by the enzyme-linked immunosorbent assay. Lipasin levels [mean ± SEM] were increased by more than two fold (P < 0.001) in the diabetic patients (5.56 ± 0.73 ng/mL) as compared to the control subjects (2.19 ± 0.24 ng/mL). Serum lipasin levels were positively correlated with BMI (rho = 0.49, P < 0.001), and showed a 35% increase 2 hours following a defined meal (P = 0.009). Therefore, lipasin/betatrophin is nutritionally-regulated hepatokine that is increased in human type 2 diabetes and obesity.
Elevated mouse hepatic betatrophin expression does not increase human beta-cell replication in the transplant setting.
The recent discovery of betatrophin, a protein secreted by the liver and white adipose tissue in conditions of insulin resistance and shown to dramatically stimulate replication of mouse insulin-producing beta-cells, has raised high hopes for the rapid development of a novel therapeutic approach for the treatment of diabetes. However, at present the effects of betatrophin on human beta-cells are not known. Here we employ administration of the insulin receptor antagonist S961, shown to increase betatrophin gene expression and stimulate beta-cell replication in mice, to test its effect on human beta-cells. While mouse beta-cells, both in their normal location in the pancreas or when transplanted under the kidney capsule, respond with a dramatic increase in beta-cell DNA replication, human beta-cells are completely unresponsive. These results put into question whether betatrophin can be developed as a therapeutic for human diabetes.
Detection of C-terminal Betatrophin Peptide in Human Plasma and Rodent Liver.
Betatrophin protein, also known as heptaocellar carcinoma-associated protein TD26, has been identified as a specific hormone that promotes (1) pancreatic ß cell proliferation and (2) lipid regulation1. Methods were developed in this study to detect and characterize both the betatrophin protein and its C-terminal fragment in mouse liver, rat liver, and human plasma. Based on bioinformatics analysis, potential enzyme cutting sites were selected along the betatrophin protein. Peptide fragments corresponding to the N-terminal, middle, and C-terminal regions of the protein were prepared via solid phase peptide synthesis and antibodies were raised against these regions. Immunohistochemistry shows that liver cells are stained with the C-terminal betatrophin antibody. Western blot analysis shows the C-terminal betatrophin antibody is able to recognize both the 22 kD full length betatrophin protein as well as a smaller C-terminal fragment peptide in human plasma. The C-terminal betatrophin fragment can also be identified by HPLC and MALDI-TOF from the fractions subject to antibody-mediated affinity purifications. Furthermore, radioimmunoassays (RIA) and enzyme immunoassays (EIA) confirm the presence of C-terminal peptide in human plasma, with levels ranging from 0.4 ng/ml to 4 ng/ml. Immunoassays of liver tissue homogenates also indicate the presence of C-terminal betatrophin peptide with a level around 40.5 ng/g of liver tissue. In agreement with previous reports by Quagliarini et al2., we found that plasma betatrophin levels increased after refeeding. We also observed an increase of C-terminal betatrophin levels in plasma as determined by magnetic bead RIA. Although the sensitivity of EIA and RIA may differ, the plasma level of betatrophin was similar, irrespective of the assay procedure. In conclusion, our methods indicate the level of C-terminal betatrophin peptide in plasma may reflect an increase or decrease of full-length betatrophin metabolism.
Jaw-Kang Chang, Rong-Ming Lyu1, Xiang-Qun Chen, et al., Japanese Peptide Symposium/APIPS2013 conference.
Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis.
Angiopoietin-like protein (ANGPTL)8 (alternatively called TD26, RIFL, Lipasin, and Betatrophin) is a newly recognized ANGPTL family member that has been implicated in both triglyceride (TG) and glucose metabolism. Hepatic overexpression of ANGPTL8 causes hypertriglyceridemia and increased insulin secretion. Here we examined the effects of inactivating Angptl8 on TG and glucose metabolism in mice. Angptl8 knockout (Angptl8-/-) mice gained weight more slowly than wild-type littermates due to a selective reduction in adipose tissue accretion. Plasma levels of TGs of the Angptl8-/- mice were similar to wild-type animals in the fasted state but paradoxically decreased after refeeding. The lower TG levels were associated with both a reduction in very low density lipoprotein secretion and an increase in lipoprotein lipase (LPL) activity. Despite the increase in LPL activity, the uptake of very low density lipoprotein-TG is markedly reduced in adipose tissue but preserved in hearts of fed Angptl8-/- mice. Taken together, these data indicate that ANGPTL8 plays a key role in the metabolic transition between fasting and refeeding; it is required to direct fatty acids to adipose tissue for storage in the fed state. Finally, glucose and insulin tolerance testing revealed no alterations in glucose homeostasis in mice fed either a chow or high fat diet. Thus, although absence of ANGPTL8 profoundly disrupts TG metabolism, we found no evidence that it is required for maintenance of glucose homeostasis.
Betatrophin: a hormone that controls pancreatic ß-cell proliferation.
Replenishing insulin-producing pancreatic ß cell mass will benefit both type I and type II diabetics. In adults, pancreatic ß cells are generated primarily by self-duplication. We report on a mouse model of insulin resistance that induces dramatic pancreatic ß cell proliferation and ß cell mass expansion. Using this model, we identify a hormone, betatrophin, that is primarily expressed in liver and fat. Expression of betatrophin correlates with ß cell proliferation in other mouse models of insulin resistance and during gestation. Transient expression of betatrophin in mouse liver significantly and specifically promotes pancreatic ß cell proliferation, expands ß cell mass, and improves glucose tolerance. Thus, betatrophin treatment could augment or replace insulin injections by increasing the number of endogenous insulin-producing cells in diabetics.
Emerging roles of Lipasin as a critical lipid regulator.
Patients with metabolic syndrome are at high risk for developing atherosclerotic cardiovascular diseases and diabetes. In addition to total cholesterol, LDL-C and HDL-C, elevated plasma triglycerides (TG) are increasingly recognized as an independent risk factor for cardiovascular diseases. Recently 3 groups independently reported the identification and characterization of a novel blood lipid regulator, Lipasin/RIFL/ANGPTL8, which here is referred to as Lipasin for its lipoprotein lipase inhibition effect and for being a circulating factor denoted by 'in'. Being highly enriched in the liver, Lipasin is a hepatocyte-derived circulating factor that regulates plasma TG levels. Lipasin is nutritionally regulated, as its mRNA levels in liver and fat as well as its protein level in serum are reduced by fasting. Mice deficient for Lipasin have lower serum TG levels; conversely, its adenovirus-mediated overexpression increases serum TG levels, in part, through promoting ANGPTL3 cleavage, releasing its N-terminal domain that inhibits lipoprotein lipase. Lipasin sequence variations are associated with LDL-C and HDL-C concentrations in humans. Being lipogenic, Lipasin is highly induced during adipogenesis. Levels of Lipasin and ANGPTL4 show opposite changes in response to fasting or cold environment. Lipasin, a novel but atypical ANGPTL family member, is emerging as a critical lipid regulator and a potential drug target.
Lipasin, thermoregulated in brown fat, is a novel but atypical member of the angiopoietin-like protein family.
Hyperlipidemia is a major contributor to cardiovascular diseases. Members of the angiopoietin-like protein family (ANGPTLs) are important determinants of blood lipid levels. Lipasin, a newly identified gene that regulates serum triglycerides, is homologous to ANGPTL3's N-terminal domain, which is sufficient and necessary for blood lipid regulation. Brown fat is critical in mediating energy homeostasis. Thermogenesis is the primary function of brown fat, in which Lipasin and some ANGPTLs are abundant; it is unknown, however, whether these genes are thermoregulated. We therefore comprehensively examined the thermoregulation of Lipasin and ANGPTLs in brown fat. Here we show that Lipasin is a novel but atypical member of the ANGPTL family because it is within the same branch as ANGPTL3 and 4 by phylogenetic analysis. The mRNA levels of Lipasin are dramatically increased in the cold environment (4 °C for 4 h) whereas those of ANGPTL4 and ANGPTL2 are suppressed. Fasting dramatically suppresses Lipasin but increases ANGPTL4. High-fat diet treatment increases Lipasin, but reduces ANGPTL2. The distinct transcriptional regulations of Lipasin, ANGPTL2 and ANGPTL4 in brown fat in response to cold exposure and nutritional stimulation suggest distinct physiological roles for ANGPTL family members in mediating thermogenesis and energy homeostasis.
The metabolic syndrome, a common disorder including glucose intolerance and dyslipidemia, poses a major public health issue. Patients with high blood lipids, such as triglycerides, are at high risk in developing atherosclerotic cardiovascular diseases. To identify genes involved in metabolism, we performed RNA-seq experiments on the liver and fat in mice treated with a high-fat diet or fasting, and identified Gm6484 (named Lipasin) as a novel nutritionally regulated gene. Human LIPASIN is liver specific, while the mouse one is enriched in the liver and fat, including both brown and white adipose tissues. Obesity increases liver Lipasin, whereas fasting reduces its expression in fat. ANGPTL3 (Angiopoietin-like 3) and ANGPTL4 are critical regulators of blood lipids. LIPASIN shares homology with ANGPTL3's N-terminal domain that is needed for lipid regulation, and with ANGPTL4's N-terminal segment that mediates lipoprotein lipase (LPL) binding. Lipasin overexpression by adenoviruses in mice increases serum triglyceride levels, and a recombinant Lipasin inhibits LPL activity. Therefore, a potential mechanism for Lipasin-mediated triglyceride elevation is through reduced triglyceride clearance by LPL inhibition. Lipasin is thus a novel nutritionally-regulated liver-enriched factor that plays a role in lipid metabolism.
Atypical angiopoietin-like protein that regulates ANGPTL3.
Angiopoietin-like proteins (ANGPTLs) play major roles in the trafficking and metabolism of lipids. Inactivation of ANGPTL3, a gene located in an intron of DOCK7, results in very low levels of LDL-cholesterol (C), HDL-C and triglyceride (TAG). We identified another ANGPTL family member, ANGPTL8, which is located in the corresponding intron of DOCK6. A variant in this family member (rs2278426, R59W) was associated with lower plasma LDL-C and HDL-C levels in three populations. ANGPTL8 is expressed in liver and adipose tissue, and circulates in plasma of humans. Expression of ANGPTL8 was reduced by fasting and increased by refeeding in both mice and humans. To examine the functional relationship between the two ANGPTL family members, we expressed ANGPTL3 at physiological levels alone or together with ANGPTL8 in livers of mice. Plasma TAG level did not change in mice expressing ANGPTL3 alone, whereas coexpression with ANGPTL8 resulted in hypertriglyceridemia, despite a reduction in circulating ANGPTL3. ANGPTL8 coimmunoprecipitated with the N-terminal domain of ANGPTL3 in plasma of these mice. In cultured hepatocytes, ANGPTL8 expression increased the appearance of N-terminal ANGPTL3 in the medium, suggesting ANGPTL8 may activate ANGPTL3. Consistent with this scenario, expression of ANGPTL8 in Angptl3(-/-) mice failed to promote hypertriglyceridemia. Thus, ANGPTL8, a paralog of ANGPTL3 that arose through duplication of an ancestral DOCK gene, regulates postprandial TAG and fatty acid metabolism by controlling activation of its progenitor, and perhaps other ANGPTLs. Inhibition of ANGPTL8 provides a new therapeutic strategy for reducing plasma lipoprotein levels.
RIFL aims to be a new player in lipid metabolism.
RIFL (refeeding induced in fat and liver) is highly expressed in brown and white fat as well as in liver. In white adipose tissue and liver, RIFL expression is induced by refeeding and is also elevated in ob/ob mice. The function of RIFL is unknown, and there is some evidence to suggest it may be secreted. RIFL expression is induced during adipogenesis in rodent and human model systems, and cellular knockdown and mouse knockout studies demonstrate that RIFL expression correlates with lipid levels. Overall, these studies indicate that RIFL is a new important player in lipid metabolism.
Identification of RIFL, a novel adipocyte-enriched insulin target gene with a role in lipid metabolism.
To identify new genes that are important in fat metabolism, we utilized the Lexicon-Genentech knockout database of genes encoding transmembrane and secreted factors and whole murine genome transcriptional profiling data that we generated for 3T3-L1 in vitro adipogenesis. Cross-referencing null models evidencing metabolic phenotypes with genes induced in adipogenesis led to identification of a new gene, which we named RIFL (refeeding induced fat and liver). RIFL-null mice have serum triglyceride levels approximately one-third of wild type. RIFL transcript is induced >100-fold during 3T3-L1 adipogenesis and is also increased markedly during adipogenesis of murine and human primary preadipocytes. siRNA-mediated knockdown of RIFL during 3T3-L1 adipogenesis results in an ~35% decrease in adipocyte triglyceride content. Murine RIFL transcript is highly enriched in white and brown adipose tissue and liver. Fractionation of WAT reveals that RIFL transcript is exclusive to adipocytes with a lack of expression in stromal-vascular cells. Nutritional and hormonal studies are consistent with a prolipogenic function for RIFL. There is evidence of an approximately eightfold increase in RIFL transcript level in WAT in ob/ob mice compared with wild-type mice. RIFL transcript level in WAT and liver is increased ~80- and 12-fold, respectively, following refeeding of fasted mice. Treatment of 3T3-L1 adipocytes with insulin increases RIFL transcript ?35-fold, whereas agents that stimulate lipolysis downregulate RIFL. Interestingly, the 198-amino acid RIFL protein is predicted to be secreted and shows ~30% overall conservation with the NH(2)-terminal half of angiopoietin-like 3, a liver-secreted protein that impacts lipid metabolism. In summary, our data suggest that RIFL is an important new regulator of lipid metabolism.
Identification of genes differentially expressed in human hepatocellular carcinoma by a modified suppression subtractive hybridization method.
To identify differentially expressed genes in human HCC in China, we applied a modified SSH method for cDNA subtraction. Such modification has made the method more effective for subtraction. We have obtained 36 and 24 differentially expressed cDNA fragments after modified SSH from 4 paired samples of human HCC and non-HCC tissues, respectively. Reverse Northern blotting analysis was performed to further identify the genes differentially expressed in the HCC and non-HCC tissue samples. There were 25 genes really overexpressed in HCC, and their corresponding encoding molecules may reflect the events of cell accelerated metabolism, proliferation, angiogenesis, anti-apoptosis, tumorigenesis (TLH107, TFH9) and the potential for metastasis. Of the 25 genes overexpressed in HCC, 5 were novel and their full-length cDNAs were cloned. These 5 novel genes are functionally associated with the occurrence and development of HCC according to the Database analysis. In the paired non-HCC tissues, there were 15 genes lowly or not expressed in HCC, and their encoding proteins function as tumor suppressors (TFA3, TFA11), acute-phase reactive proteins, and the blood plasma proteins that are mainly or exclusively synthesized in the liver. The distinct profiles of the differentially expressed genes in HCC and the paired non-HCC tissues have partially reflected the genetic alterations during HCC tumorigenesis. The novel HCC-specific gene TLH6 and the CT antigen encoding gene TLH107 may have diagnostic and therapeutic potentials in HCC and/or other solid cancers.


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Due to the enthusiastic response for Princess’ return to world cruising, the line will offer two global itineraries in 2009, giving twice as many passengers the opportunity to enjoy this unparalleled travel experience, as the ships take them to more than 40 destinations on six continents. For the first time, Princess will offer world cruising on two sister ships, with both voyages commencing at nearly the same time.
The 670-passenger Tahitian Princess and 710-passenger Royal Princess will offer similar 107-day itineraries that set sail from Ft. Lauderdale in January 2009. The Tahitian Princess sailing leaves on January 14, ending in Dover, while Royal Princess sails on January 20 and winds up in Rome. In addition, passengers can choose from two extension options for the Tahitian Princess voyage, giving world travelers the option of finishing this journey of a lifetime in Dover, Rome, Stockholm or New York. Both itineraries feature travel to South America, the South Pacific, Australia, Asia, India and Egypt, with differing European segments. Each voyage will call at a brand new port for Princess — Port Blair in the Andaman Islands, a picturesque stop in the Indian Ocean.
Tahitian Princess and Royal Princess will both set sail from Ft. Lauderdale on similar itineraries that begin with a visit to Grand Cayman and a transit of the Panama Canal on the way to Quito (Manta), Ecuador. Passengers will enjoy an overnight stay in Lima (Callao), Peru where they can visit the dramatic ruins of Machu Picchu. An unusual opportunity to visit Easter Island follows, and the ships will cruise by historic Pitcairn Island as well.
The tropical pleasures of Tahiti (Papeete) and Rarotonga are next to delight passengers as the ships then head “Down Under” for Auckland and the Australian ports of Burnie (Tasmania), Sydney, Brisbane, and Cairns (for visits to the Great Barrier Reef). Next up are Rabaul (Papua/New Guinea) and Guam, followed by the mysteries of Asia with calls to Osaka (for Kyoto), Hiroshima, Seoul (Inchon), Shanghai, Hong Kong, Ho Chi Minh City (Vietnam), Sihanoukville (Cambodia) Bangkok, Singapore, and Kuala Lumpur (Port Kelang) in Malaysia.

industry_corpus2: Transportation


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Myanmar is one of those rare places of allure — especially for a travel photographer — that is difficult to resist. It is without a doubt one of the most enjoyably photogenic places in the world, made all the more so for the fact that most Burmese like being photographed. What’s more, once you’ve been, it’s even more difficult to resist returning. Not just to get the shots you missed or discover more places, but because you miss the way it makes you feel, which really is something bordering on the magical. It is THE perfect place to participate in a photo tour workshop.
Not to worry, Myanmar is also one of the safest travel destinations in the world, despite the distorted impression the media gives. Please read this article for more information. And here’s a recent article from Luminous Journeys client Lisa DeSimone, which will let you know how most everyone who visits Myanmar feels about their experiences.
LJ’s Burma travel photography tours take full advantage of our award winning Western & native professionals to gain insider access to places and people no other tours can match. Each Journey is supported by the very best travel & logistics people in the country. In fact, our own Soe Soe Lwin ran Steve McCurry’s Myanmar photo tour every year for nearly a decade, before moving to found LJ in 2012.
Iconic Myanmar – Golden Triangle Expedition… The inspirational brilliance of A.P. Soe returns to bring you the classic grandeur of his homeland, as well as guide you off the beaten path and into the heart of The Golden Triangle and its colorful tribal groups during the rice harvest!
Photographers Gone Wild – Chin State Expedition is one of our 3-time Myanmar Photographer of the Year‘s favorite Burma photo tour itineraries. K.K. Winn is the ultimate Myanmar photography insider, who knows the light, locations and people of Myanmar like no one else.
Photograph Myanmar’s Big 4 iconic destinations plus explore the spectacular Lost City of Mrauk U and environs, which includes a remote river journey to the few vanishing “tattoo tribes” remaining in Rakhine State.
Your leader on this photo tour is multi-major award winning Fuji X photographer, Kyaw Kyaw Winn. K.K.’s passion for photography is infectious and his congenial nature makes all his photo adventures a sheer joy.
PLEASE NOTE: While news reports of military action in remote Myanmar in 2017 were tragic, please understand that Myanmar remains one of the friendliest, most welcoming, and SAFEST travel destinations anywhere in the world. Safer than neighboring Thailand, far safer than Mexico, even safer than the EU or United States. This is a fact. For more insight, including addressing concerns over the ethical question, please read the top section and conclusion of this informative article.
By far the most important religious site in the country, Shwedagon Pagoda dominates the Yangon skyline. At 325 feet in height, the 2,500 year old spiritual center of Myanmar is covered in over 50 tons of gold and topped with thousands of precious stones. At least once during their lives, all Buddhists throughout the largest nation in SE Asia, do their best to make pilgrimage to the great Pagoda, said to have been sanctified in person by the Buddha himself. Getting perspective on Shwedagon is the biggest challenge for the photographer. This is most easily and best done outside the pagoda grounds, in nearby streets or from People’s Park. It’s there that its enormous size and beauty can be fully appreciated.
Perspective from inside the grounds is more difficult. It’s often helped near sunset time and blue our when monks scale the golden heights to clean. It should be pointed out however, that there is much to photograph inside the grounds that either don’t involve the pagoda itself, or use it in various ways as backdrop. This includes worshippers praying with burning incense, pilgrims pouring cups of water over Buddha figures, monks walking or in meditation, giant bells, and numerous pavilions with large Buddha’s and inlayed Buddhist art. One can spend many hours here and visit many times and still be captivated by new things and new, ever changing scenes. Myanmar was originally dubbed ‘The Golden Land’ because of the many thousands of gold pagodas, temples and shrines that are found all over the country. We would be remiss not to mention the second and third most holy (and golden) sites, which are the Golden Rock of Kyaiktiyo (4.5 hour drive from Yangon), and the Mahamuni Buddha in Mandalay. The former clings impossibly to a thousand foot cliff, while the latter was part of the spoils of war when the Bamar army defeated the Mrauk U Empire in 1684.
Second only to Shwedagon in importance, are the 2,220 surviving temples of Bagan, which is without question one of the great archaeological sites of the world. During its reign at the royal capital of a vast Southeast Asian kingdom, Bagan served as the world’s epicenter of Theravadan Buddhism for nearly a thousand years. When the light is good and the mist is rising, its templescape borders on the surreal.
Other photogenic locations include – the extraordinary and little visited Lost City of Mrauk U; the massive, earthquake split temple of Mingun first made famous by Steve McCurry in National Geographic; the all-white Hsinbyume Pagoda, also at Mingun on the Irrawaddy River; the largest teak structure in the world, the U Bein Bridge at Amarapura; the multi-colored vegetable and flower fields and old school farmers of Aung Ban; the rice paddies, wonderful Buddha caves and karst limestone formations of Hpa An; and the gorgeous mountain rice terraces of Kyaing Tong. Also worth mentioning, although not part of any publicly offered Myanmar photo tours because of their remoteness, are the 808 virtually virgin tropical islands of the Myeik Archipelago, and the rarely visited eastern Himalayas, where new species of flora and fauna are discovered every year.
Myanmar is unique in Asia in many ways. One of the most visible ways is the presence of Buddhist monks in and nuns of all ages out and about in everyday life. Early mornings across the country you will see and be able to photograph them on their alms rounds, when they are out collecting rice and other things in large black bowls. This might be in city streets, country lanes with temple backdrops, or along the berms of rice fields. Monks and nuns form single file lines according the height and rank, with the little novices towards the rear. Lines can be just a few monks or nuns, a dozen or two, and up to 1,000 during special events, such as the Ananda Pagoda Festival in Bagan.
The greatest number of monasteries and nunneries is in Mandalay, where there are more than 600. It’s here where you see them most often out doing mundane things, like perusing mobile phone shops or buying vegetables at a street market, or even kicking the soccer ball around.
Nuns in pink robes, which are found no place else, keep different schedules than the monks. Alms rounds are limited to once or twice a week, and they are more likely to have nunnery staff perform outside duties . While not seen on the streets as often as monks, you still see them often as each nunnery will have varying schedules and rules. We often visit nunneries and have good working relationships with them. They are perfectly happy to have us visit and photograph, and most of our participants walk away enchanted by the experience. Even the tough guys!
Thanaka paste is quintessentially Myanmar. It’s made from the Thanaka tree, branches of which you will see sold at street and country markets throughout the country. Most people still DYI, but small, manufactured jars of the stuff are becoming increasingly popular. You just mix a portion with a little water and apply it however you like. Some just slop it all over, including their bodies, others do nice designs like Bodhi leaves. Moms have been known to paint Mickey Mouse on their kids. Getting some nice portraits or capturing scenes where Thanaka is involved, are one of the ‘must gets’ on the shot lists of excited Myanmar photo tour participants.
Wearing the paste serves multiple purposes, as makeup by girls, adornment for boys, sunscreen, and as claimed by teens, acne inhibitor! In case you’re wondering, monks and nuns do not wear Thanaka. It’s not a religious custom either, as resident Muslims and visitors of all faiths or none are welcome to wear it! In fact, the Burmese love it when visitors give it a go. Pick a style, any style!
Other than Bagan, Inle Lake is Myanmar’s most talked about destination. And the most talked about at Inle among photographers is of course the inimitable Intha fisherman who ply a living from its waters. With their broad hats, one leg rowing style, conical nets, mirror like reflections and mountain background, it’s easy to see why. To fish, the Intha find a good spot, push their nets vertically to the lake bed by foot, and often pound the water with their oars to scare up the fish. Sunrise is the best time to catch them if you can, with the mists and ethereal light of December and January being the best time of year.
In addition to the fishermen, another favorite place for exploration and photography, is the hundreds of ancient temple ruins at Nyaung Oak, near the village of Indein. Indein is also home to the best 5-day market, where tribes form all over the area come down from the hills to shop and trade. If you like photographing markets and different peoples in various traditional garb, this is the best place to come.
On the lake itself “floating” Buddhist temples are numerous, as well as monasteries, villages built on stilts and floating gardens of assorted fruits and vegetables. Including 70% of Myanmar’s tomatoes! Cottage industries that can make for interesting travel photography, include cheroot rolling, umbrella making, rice pasta making, cheroot rolling, silver-smithing, and lotus silk weaving.
Complaints you may hear about Inle being over-touristed, are laughable. It’s a big lake and it’s easy to get lost among its endless canals and floating villages no tourist ever sees, where the heart of lake’s “magic” can be felt. Myanmar is a very under-touristed country for all it has to offer, which is all the more reason for photographers to come! Let the average tourists who choose not to understand how safe and wonderful and enriching the country is for travelers to experience, stay home. It makes is all the better for us! Photographers do their research.
There are 8 main tribal groups in Burma, with more than 135 offshoots or ethnicities among them. The main tribes are the Bamar, Mon, Shan, Chin, Kayan, Rakhine, Kachin, and Kayah. Others include the Wa, Naga, Lahu, Lisu, Palaung, Akha and En. To this day many still wear traditional dress and live much as they have for centuries. This is increasingly rare around the world, where even in places like Papua New Guinea where – outside the festivals – they are already wearing T-shirts with company logos on them! Myanmar offers an extraordinary opportunity for documentary and travel photographers to do what they love, while contributing to the general documentary archive of vanishing peoples.
These tribes can be found in many regions of the country, but only some are reasonably accessible within a limited time frame. Some are not accessible at all, except for the true adventurer willing to handle the hardships and risks. Most villages are very welcoming, but don’t try this on your own. A local guide or fixer who knows what they are doing is essential. First to locate the villages and get you there, then for making contact and seeking permission to photograph. They speak their own dialects, and many do not speak much if any Burmese.
Critical to the process is knowing when to show up. Try showing up at 10 am on a work day, and you may well find only a few elderly folks and toddlers around. All the more reason to Get Luminous, and let us do the heavy lifting.
Not only is Yangon probably the friendliest major city in the world, but it’s also one of the great unsung locations for one of kind, striking street photography. While the city is undergoing a building transformation with new hotels and shopping centers going up, (along with numerous British colonial buildings being restored to their former glory), Yangon is still largely a decaying masterpiece for the street photographer, providing a rich tapestry of backgrounds and anachronistic settings. Within the settings are of course the diverse and welcoming people going about their daily lives.
Any town or village in Burma is great for street photography. It’s like stepping back in time and being able to photograph as if it were 100 years ago, with some modern exceptions. It’s all up to the frames you choose. Mandalay is burgeoning with street opportunities, and is second only to Yangon in that regard. Just walk the streets anywhere and you will see. But when you do, if you are sure to be open and engage, things will open for you in response. With some exceptions, it’s not a place to blend or hide and be unnoticed like a New York or San Franciso, and it’s impossible anyway! The people of Myanmar are remarkably warm and welcoming.
The new and modern capital city of Naypyidaw, with its massive buildings and wide boulevards, can provide a great contrast the streets of Yangon and Mandalay, as part of a photo essay. To give you some idea, see Nic Dunlop for his series of fantastic images made there a few years ago.

industry_corpus2: Travel & Geography


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Looking for some fun ways to teach patterns? Today I’m sharing a big variety!
Basic math skills in preschool and kindergarten set the foundation for learning more advanced math concepts later on. Patterning is one of those important early skills. Thankfully, patterns are easy and fun to teach!
Read on for 15 simple ways to teach your early learner about patterns. At the end of the post you’ll find a variety of free printables as well!
2. Make a pattern with toys. We love to make patterns with Duplos. Making patterns with toy vehicles is fun too.
4. Make a sound pattern with rhythm instruments. BANG, tap, tap, BANG, tap, tap. Start out by making a pattern and having your child copy you.
5. Get out a colored manipulative and make patterns. We like to use color tiles, counting bears, and pattern blocks. You could also put pom poms in an ice cube tray.
6. Make patterns with stickers.
7. Save lids and make a variety of patterns.
8. Create patterns with objects you find in nature.
9. You can make a pattern with everyday household objects.
Fork, knife, spoon, fork, knife spoon.
Big book, small book, big book, small book.
10. Have your child make her own patterns using stamps and washable ink pads.
11. Draw simple patterns using crayons.
12. Make patterns by sliding balls of play dough onto skewers.
13. Use coins to make patterns.
14. Notice patterns you see everyday. Have your child find the tile in your bathroom floor, the pattern in your backyard gate, or the pattern in the picture frame on his wall. Pretty soon he’ll be finding patterns to show you!
15. Here’s a fun one – make patterns using snack food. Pretzel, cracker, raisin, raisin. Pretzel, cracker, raisin, raisin.
Get these printable Duplo pattern towers from All Our Days.
Get free M & M pattern cards from Teach Beside Me.
I’ve shared counting bear pattern strips.
My truck pattern strips are one of the first printables I shared at The Measured Mom.
Print these coin pattern strips.
Follow The Measured Mom’s board Preschool Math on Pinterest.
I’m a future teacher (Early Childhood Ed) living in the Bahamas and your website has been a blessing to me. So grateful for the resources. Thanks a mill!
That’s so wonderful to hear, Shantell! Blessings on your education!
i have been wondering how to go about teaching patterns, I can now find the easiest way ever! so straightforward. Thanks a zillion times.

industry_corpus2: Subject Education


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Stay at Milsoms, Milsoms Kesgrave Hall or The Pier in Harwich during April and take advantage of this fabulous offer.
Enjoy an overnight break at Maison Talbooth with champagne, complimentary spa treatment and three-course dinner this Spring.
Stunning selection of luxury hotels in Essex and Suffolk.
From the inspiring settings of Constable Country to the unique appeal of the Essex coast, we have a range of luxury hotels. Discover the beautiful Dedham setting of Maison Talbooth and Milsoms, explore the old town of Harwich when staying at The Pier or enjoy the Suffolk countryside at Milsoms Kesgrave Hall.
Whether you’re looking for an overnight stay, a weekend retreat or a family break, you can be assured of an unforgettable experience.
Experience great food, great wine and great service.
Whether you’re looking for delicious food beside the River Stour, the finest sea food on the Essex coast or relaxed, indoor and outdoor dining all day, every day, our stunning selection of restaurants will have exactly what you fancy. Choose from Le Talbooth’s award-winning menus, the Harbourside’s freshly-caught specialities or, if you’re looking for a more flexible option, the restaurants at Milsoms Kesgrave Hall, Milsoms and The Pier.
Milsom Hotels & Restaurants are perfect for weddings and events.
Whether you’re exchanging vows on your special day, informally meeting clients and suppliers or arranging a corporate conference, we have a great selection of private spaces available.
Whichever location you choose, you can be assured of outstanding service, privacy, quiet and all the equipment and supplies you’d expect to have on hand.
Enjoy a private dining space for you and your guests.
We have a number of fantastic spaces which are ideal for birthdays, celebrations or corporate events. Enjoy an unforgettable experience with friends and family or host a professional event in great surroundings.
With dedicated teams and fantastic locations, you’re sure to have an experience to remember.
Step back, relax and indulge in the Treatment Rooms.
From the heated outdoor swimming pool and hot tub to the relaxing Treatment Rooms spa, Maison Talbooth is the perfect place to unwind.
Be prepared to be pampered from the moment you arrive at the Treatment Rooms. Whether you’ve booked a treatment or are visiting as part of a day package, you’ll enjoy an experience that soothes and reinvigorates.
Discover the latest Special Offers from Milsom Hotels & Restaurants.
If you’re looking for a great overnight package, a fabulous deal for a weekend away or simply want to come along to a specific event, then take a look through our latest offers to find the one that’s just right for you.
Please browse through the full set of our latest offers across all our properties and then simply let us know which one you’d like to take advantage of.
We’re glad that you’re visiting our website and we’d love to welcome you to one of our restaurants or hotels.
We only employ merchants of happiness within our organisation, we only serve the best food and drink and we only make the comfiest beds!
Each of our Essex and Suffolk locations offers all day (no need to book) dining in our restaurants (inside or outdoors) as well as booked tables at The Pier or our riverside restaurant Le Talbooth in Dedham.
We define our brand and product as Great places to eat, drink and stay™ and by that we mean we aim to deliver an exceptional service and product at every one of our locations, to every guest, on every visit.
Find out more about our restaurants, hotels, events, weddings or contact us.
Stay at The Pier, Milsoms or Milsoms Kesgrave Hall in April and enjoy a three-course dinner, overnight accommodation with full breakfast, cream tea and bottle of Prosecco in your room on arrival. Fom £115 per person.

industry_corpus2: Hospitality & Catering


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Way back in the 1970s, when NASA was contemplating the future after the Apollo moon landings, it was thinking big—really big. Two of its big ideas—Gerard K. O’Neill’s proposed space colonies and the idea of space solar power systems—were all the rage then. It was a grand vision for a space-based economy that would transform global society.
NASA’s lunar plans failed to secure US government support, and the massive funding of the 1960s moon race had come to a screeching halt by the mid-1970s. Also problematic was that NASA’s space shuttle, which first flew in 1981, never delivered on promises of low-cost access to space. Without a decrease in the cost of access, the price of space-based solar power would never be competitive with terrestrial sources of energy. Finally, we were ignorant of climate change—and coal was cheap and plentiful.

industry_corpus2: Aerospace


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At TopBorn we’re working to help businesses with digital solutions that make their digital presence more valuable. Our interest in the digital world is massive and we have several years of experience, developing and building up the skills required to deliver the very best solutions on web use and communication. Would you as a company in Rawtenstall have a need for graphic design or a graphic profile of top class, please get in touch.
With modern tools, technical knowledge and an eye for graphic design, we help you as a company in Rawtenstall to reach more customers with greater effect. Look around, and familiarize yourself with our services here on our site. Contact us, and we can start our work to increase your chances of more jobs and better profitability.

industry_corpus2: Computing & Telecommunications


text: CAIR-Chicago met with the Arab American Action Network at the CAIR-Chicago office to develop strategies for the next phase of the Citizenship Delay Project. The next phase of the project will include a political/media campaign to raise awareness and garner public support, legal remedies for the dozens of cases that have been reported to both organizations on the issue, outreaching to the Muslim community to spread awareness on the issue, and a publication that will detail the course of the project and the findings of research and investigation on the issue. As a joint effort with the Arab American Action Network (AAAN), CAIR-Chicago is asking individuals who passed a citizenship examination and have been waiting for over 90 days, or have been waiting for a Green Card for permanent residence for over 90 days to contact us at either civilrights@cairchicago.org or mennakhalil@gmail.com.

industry_corpus2: Politics & Administration


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Blackjack is a game of both aptitude and fortunes thus it should be drawn nearer in an alternate manner to numerous other casino games. Blackjack requires the player to have both a sensible sound judgment standpoint and a measure of commitment. Toss in an energy for the game and a capacity to acknowledge certainty and you have a triumphant measure. Be that as it may, the odd formula of methodologies obliges cautious taking care of for the game to remain fun whilst demonstrating lucrative in the meantime.
It is fundamental that you have an arrangement. You have to know your expects to have the capacity to make objectives and stick to them. Separate them into a progression of basic and simple to oversee littler steps which ought to educate your choices in each hand you play. On the off chance that you dismiss your objective then you won’t accomplish it. Whether the objective is to complete first in as blackjack competition or to make a sure measure of cash, the objective ought to delineate how you approach the game. Whatever you’re objective, dependably remember it and re-run past hands to verify the moves you made mirrored your definitive points. This will help to keep you on track and help fixation.
Essential blackjack method can be found in books, online and in magazines. It has been conceived for a reason and will help you to decrease the house edge, accordingly expanding you’re possess. Fundamental blackjack procedure must be remembered, honed and played painstakingly to the letter for it to be fruitful. Practice can be accomplished through free play alternatives and low stake tables. An excess of players discover bits of data, or take easy routes, or even take in the hypothesis without the practice. These are the players who will lose over the long haul. Fundamental method offers no prompt arrangements yet with center and devotion it will demonstrate valuable over a stretch of time.
You can realize what you like, yet in the event that you don’t deal with your cash, you will never be in a triumphant position. Numerous online destinations now offer point of confinement setting administrations which will demonstrate to you when a sum has been come to. The best guidance is to never pursue misfortunes, just play what you can stand to lose, and never bet with acquired cash as this dependably must be paid back. Resource yourself breaking points and stick to them. These breaking points could be the time allotment you would be eager to play of the cash you are wiling to wager in that session. Adhering as far as possible mean stopping when come to, whether winning or losing.

industry_corpus2: Gaming


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Paris, said to be the "tribunal of beauty," has proclaimed Crown Princess Marie of Roumania as the "most beautiful princess in Europe," reports the Chicago Daily Tribune.
Her beauty is said the be "beyond question." All princesses are said to be "beautiful," but in most cases, they are the "plainest of all mortals." But Crown Princess Marie would be "declared beautiful even if she were a peasant girl."
The blood of three royal families flows through her veins. Her father, the late Duke Alfred of Saxe-Coburg and Gotha, was a son of Queen Victoria. Her mother, Marie, is the daughter of the late Alexander II of Russia. Her first cousin is Kaiser Wilhelm II of Germany.
Unfortunately, for all the eligible princes, Marie, 28, is "happily married" to Crown Prince Ferdinand of Roumania, and the mother of three young children.
Although her marriage is described as a "political" arrangement, it is a happy marriage. She was chosen to be Ferdinand's bride to "cement the ties of friendship between Russia, Germany and Romania."
Marie and Ferdinand, heir to the Roumanian throne, is a "love affair as royal marriages in Europe can be," says the Tribune.
The couple live in a "picturesque palace in Bucharest," and spend summers at Sinaia, "over which artists grow enthusiastic." She is personally involved in her children's education, and she is well educated herself. Crown Princess Marie speaks four languages, and is an accomplished musician and artist. She loves sports and enjoys riding. She also has a "great interest" in the army, and is an honorary colonel of one of guard regiments.
She always takes a prominent role at annual army maneuvers and is the "idol of soldiers" who serve in the armed forces.

industry_corpus2: Others


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• I READ with interest Awale Olad’s poignant letter (Somali youth a target, June 5).
As a young Camden resident, I would like to highlight the need for a better understanding of the fundamental issues concerning young people especially within ethnic communities.
It is simply not enough for councillors and the council leader to make empty promises when it comes to youth funding.
Funding for youth facilities is absolutely vital with the summer looming.
It is obvious that young people tend to get bored over the holidays and the council needs to listen and work closely with youth clubs to ensure young men and women have places to go to during their free time.
If the council refuses to listen and continues to undermine youth provisions in youth and community projects in Gospel Oak, Haverstock, Camden Town, Regent’s Park and Highgate, then they should be prepared to take the blame for further teenage violence in the streets of Camden.


text: Domestic violence is a pervasive issue that impacts all members of a household, including pets. There is comprehensive quantitative evidence to suggest that domestic violence and pet abuse commonly co-occur; however, as the personal accounts of pet-owning survivors have started to emerge through qualitative investigation, more research is needed to understand the unique experiences of pet abuse that take place alongside instances of domestic violence. This phenomenological investigation utilized control balance theory and a feminist framework to uncover the experiences of survivors who entered their pets into an animal care program specifically designed to help during times of domestic violence escape. Data from interviews with 12 participants were compared to secondary qualitative data from anonymous animal abuse surveys at the community partner organization. A lens of interpretative phenomenological analysis was used to identify global themes related to survivors' experiences of pet ownership while escaping domestic violence. From these testimonies, pets were revealed to be important to consider in responding to domestic violence because pets not only played key roles of emotional support in the survivors' lives, but they were also threatened and harmed by abusers to control victims. Furthermore, the provision of pet care for survivors who were escaping domestic violence was determined to be a meaningful intervention. Through learning of the experiences of pet ownership along the trajectory of recovery for domestic violence survivors, advocates may be better prepared to serve clients at this intersection. Furthermore, the empirical understanding of the role of the human-animal bond in domestic violence survivorship was augmented by this study.


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This blog is published by and reflects the personal views of Abhishek Bhatnagar and Rohit Khurana (TroubleFixers) , in their individual capacity. The content provided is exactly personal.In addition, our thoughts and opinions may change from time to time. This is a necessary consequence of our open- mindedness. All information (including any links, code samples, files, opinions, reviews, etc.) here is provided on an AS IS basis without any liability whatsoever. It is not guaranteed that the information is 100% accurate though every effort is made to make it as accurate as possible. By reading and/or using any information given on TroubleFixers (in the past, present and future), you agree that you are on your own and bear full responsibility of the risk or any harm that may occur to you or others (because of you) in any way whatsoever. You also agree that we (Abhishek Bhatnagar and Rohit Khurana OR TroubleFixers) will not be liable for any damages that you or others (because of you) may incur.
Please note that by posting any comments on this blog, you agree that you are fully aware of what you are posting as your comment and agree that you are not posting any copyrighted material which you are not allowed (legally) to post & take full responsibility for the contents of your comment and no one but you will be held liable in case of any enquiries or prosecution by any government authorities. You also agree that this blog is not to be used as a marketing gimmick or for any SEO purposes & we(Abhishek Bhatnagar and Rohit Khurana) or anyone else managing this blog can delete any part of your comment(like URLs) as deemed inappropriate, at our/their sole discretion. Your IP Address is recorded everytime when you post a comment for safeguarding our & other people’s interests.
NOTE: This Disclaimer is subject to change anytime at TroubleFixerss’ sole discretion & any changes made will be effective immediately.


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Iowa City, Iowa — The University of Iowa baseball team has placed 20 student-athletes from coast-to-coast for various summer leagues.
Three Hawkeyes are venturing to the east coast for the prestigious Cape Cod League. Sophomore Ben Norman and freshman Jack Dreyer will be teammates for the Harwich Mariners, while freshman Ben Probst will compete for the Hyannis Harbor Hawks. It is the second straight summer Iowa has been represented in the Cape Cod League.
Six players will play in the Northwoods League for two teams. Sophomores Grant Judkins and Derek Lieurance along with freshman Cam Baumann will pitch for the LaCrosse Loggers, while juniors Mitchell Boe and Shane Ritter and freshman Brett McCleary will play for the Fond Du Lac Dock Spiders.
Five Hawkeyes will compete in the Prospects League on three different teams. Sophomores Justin Jenkins, Lorenzo Elion, and junior Chris Whelan will play for the Terre Haute Rex. Freshman Matt Berst will catch for the Kokomo Jackrabbits and sophomore Kyle Crowl will play for the Quincy Gems.
Redshirt freshman Kace Massner and freshman Zion Pettigrew will play in the California Collegiate League for the Neptune Beach Pearl. Junior Tanner Wetrich, meanwhile, will play in the Coastal Plains League for the Macon Bacon.
Junior Luke Farley and freshman Connor McCaffery will play locally in the Iowa Valley League for the Watkins Mudhens and Red Top Toppers, respectively. Sophomore Grant Leonard will pitch for the Lombard Orioles in the Chicago Suburban Baseball League.

industry_corpus2: Sports


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The modernized world needs modern lighting and to make this happen LEDMyplace brings for you LED Flush Mount Ceiling Lights designed in stunning way that will make your indoors looks stunning. LED Flush Mount Ceiling Lights offers you switchable color temperature from 3000K to 5000K with lumens output up to 1700+lm.
This LED Flush Mount Ceiling Lights is having a dimmable feature which leads you to control the brightness according to your needs, and it can reinstate you old (MH) metal-halide fixture up to 65 watt. And if you're having a low ceiling then these lights will be the best choice available.
LEDMyplace offers variants design of to choose from like- Single Ring, Double Ring, and Mushroom design. So ready to make your place look stunning, contact our customer expert on (888-972-6211).

industry_corpus2: Manufacturing


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Every week brings task lists, emails, files, and new jobs. How much of that is different from the work you’ve done? Odds are, not much. A number of our tasks are variations on something.
Do not reinvent the wheel each single time you start something new. Rather, use templates–standardized files with formatting and text as starting point for new work. As soon as you save a version of the template add, remove, or alter any data for that record, and you are going to have the new job completed in a fraction of this time.
Programs work anywhere: in word processors, spreadsheets, project management apps, survey programs, and also email. Here’s how to generate documents from a template — and the way to use templates from your favorite programs –so it’s possible to get your ordinary tasks done faster.
Templates take time to build, and it’s easy to wonder whether they are worth the investment. The answer: absolutely. Editing a template requires far less time than formatting some thing from scratch. It’s the distinction between copying and pasting some text, or retyping it.
That is only one benefit: Using a template means you’re not as likely to leave out key info, also. For instance, if you need to send freelance authors a contributor arrangement, changing a standard contract template (rather than writing a new contract every time) ensures you won’t leave out that crucial clause regarding possessing the content once you’ve paid for it.
Templates additionally guarantee consistency. Perhaps you send investors or clients regular project updates. With a template, you understand the update will have the formatting, layout, and general structure.
First, templates must be comprehensive. So err on the side of including also instead of too little, it is easier to delete info than add it in.
Imagine you are creating a template of your own resume. You would want to list in-depth details about your duties and achievements, so you are going to have.
You can always delete notes later on, but you might forget it when it’s not from the template.
Some tools will automatically fill in all these factors for you (more on this in a little ). But should you need to fill in the data on your own, add some text that is simple and obvious to look for so you can find text that has to be altered without a lot of work.


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- Q in open gamblers with a second place NEW TITLE!
- Q in elite jumpers NEW TITLE!
allowing me to show her!
proud of how he handled himself!
- 2012 Puppy Dog of the Year! Go Grim!!
- WD for three points under judge Camille McArdle NEW ASCA CHAMPION! Thank you Nicole Hecksel for handling him!
- Q/5 in elite regular NEW TITLE!
- Q/10 with a second place in open regular NEW TITLE!
Grim and Wyatt both earn their CGC!
Andi: Gets to move to the veterans division and has a fantastic weekend!!!
- Q/10 in elite regular NEW TITLE!
- Q with a fourth place in elite jumpers NEW TITLE!
Sookie: only trialed on Saturday and did fantastic coming back from having puppies.
- Q with a first place in open gamblers NEW TITLE!
- WD for a three point major under judge Mr. Richard Lashbrook NEW AKC CHAMPION!!!
- Select for two points.
- 4th place in 2-4 puppy dog sweeps at the HPASC Pre-Show under breeder judge Karen MacDonald.
- Q in elite regular at nationals NEW TITLE!!!
Congrats as well on the success of other Cattail Ridge dogs competing in the veterans classes as well as performance venues!!!
- WD/BOS over three specials for a five point major under breeder judge Anne Shope.. NEW ASCA CHAMPION!!!
- Qualifying score in novice b obedience (3rd leg) NEW ASCA CD!!!
All content & images on this website are copyrighted by Cattail Ridge Australian Shepherds, 2019. © All Rights Reserved.


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Dr C Rangarajan, Chairman (Economist, Former Chairman, Prime Minister's Economic Advisory council, New Delhi).
Dr. K.P.C. Gandhi, Managing Director (Founder Director, Former DIG - Forensic Labs. of undivided AP), presently Chairman of Truth Labs, India. and Advisor to the Government Andhra Pradesh, West Bengal & J & K.
Dr. M.W.Pandit (Founder Director and Retired Scientist & Former Deputy Director of CCMB).
The problem of genetic disorders in India is enormous. Millions suffer from inherited genetic diseases and the one-sixth of the world’s population living in India has never been systematically studied for the prevalence of these diseases. The fact that most of the genetic disorders found in rural India are novel in nature and have not been recorded till date, makes the task of diagnosing these disorders challenging. The Genome Foundation strives to meet the urgent need to take authentic and affordable genetic diagnostic services to the rural population in the country. We believe the foundations efforts will have a significant impact on life sciences and improve the human condition of millions.

industry_corpus2: Health & Medicine


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Expert tips and tricks to go from casual seller to side hustle and make some CASH!
A take-home worksheet will be provided for note taking and inspiration. Start your Poshmark side hustle today! Space is limited, so reserve your spot today!


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Hospital hijinks and hilarity ensue in Hospital Havoc 2! Cure deadly diseases and mortifying maladies in the sequel to the original Hospital Havoc time management sim game. Play as a budding doctor and prove your healthcare prowess through careful prioritization and diagnostic skills. Can you handle your hospital, or will havoc reign supreme?
With addictive and fast-paced gameplay, a fun soundtrack, and wacky atmosphere, Hospital Havoc 2 is something every casual and seasoned gamer should download for their iPhone, iPod, and iPad!


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King's Casino, located on the German border in Rozvadov, Czech Republic, is a hotbed for pot-limit Omaha players offering tons of cash games including high-stakes games it often live streams.
Pot limit Omaha tournament players are about to be in for a huge treat as the inaugural The Big Wrap is coming to King's Resort on April 1-8. The festival features two big tournaments with a combined €1.2 million in guarantees making it a festival pot-limit Omaha players can't miss. Of course, there are plenty of satellites to qualify cheaper, and cash games will be running around the clock throughout the festival.
The first big tournament on the schedule is The Big Wrap Warmup PLO featuring a €550 buy-in and a €200,000 guarantee. The event features three opening flights on April 1-3 where players start with 30,000 in chips and blinds increase every 30-minutes. Each flight allows for unlimited reentries throughout the late registration period that ends after the tenth blind level.
Surviving players will compete for two more days in longer 45-minute blind levels on April 4-5 until a winner is crowned.
Satellites for this event start at just €75 giving any player a chance to compete for what promises to be a huge payday.
The highlight of the festival is easily The Big Wrap PLO event running April 5-8. This event will attract some of the biggest names in poker thanks to its €2,350 buy-in and a massive €1,000,000 guarantee.
The tournament is an eight-max deep-stacked affair with players starting with 100,000 chips and blind levels increasing every 40 minutes on the two opening flights on April 5-6.
Late registration and reentries close after 14 blind levels, which is the second blind level of Day 2 on April 7. The structure is deeper after the late registration period is closed with blind levels increasing to one hour.
The final day will be played out on April 8 and of course, will be live streamed as is typically the case at King's Casino during big events.
Players can get in even cheaper to this big buy-in tournament with a handful of satellites with buy-ins ranging from €250 to €350.
You can buy into The Big Wrap PLO using PP LIVE Dollars, the partypoker's live tournament currency. The first 50 players to buy into the €1 million guaranteed The Big Wrap PLO using PP Live Dollars will be given three nights of hotel at King's Resort for free.
The Big Wrap players that choose to directly buy-in can take advantage of special hotel deals where they can enjoy five nights at King's Report for €349 or six nights for €399. These special room rates are running out fast so if interested contact Frank Koopmann via +420 735 124 100 to make a hotel reservation.


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A corporate weblog is published and used by an organization to reach its organizational goals. The advantage of blogs is that posts and comments are easy to reach and follow due to centralized hosting and generally structured conversation threads. Currently, all major browsers (including Firefox, Opera, Safari and Internet Explorer 7) support RSS technology, which enables readers to easily read recent posts without actually visiting the blog, which is very useful for low-volume blogs.
An external blog is a publicly available weblog where company employees, teams, or spokespersons share their views. It is often used to announce new products and services (or the end of old products), to explain and clarify policies, or to react on public criticism on certain issues. It also allows a window to the company culture and is often treated more informally than traditional press releases, though a corporate blog often tries to accomplish similar goals as press releases do. In some corporate blogs, all posts go through a review before they're posted. Some corporate blogs, but not all, allow comments to be made to the posts.
External corporate blogs, by their very nature, are biased, though they can also offer a more honest and direct view than traditional communication channels. Nevertheless, they remain public relations tools.
We give complete and quality blogging solutions. Let it be Internal or External, the content of the blogs, the quality of info being shared, the aesthetics of the blogs and the reach out to the common people who influence the corporate reputation and brand value, will be exceptional.


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Candy Canes Banned Because They're Shaped Like A "J" As In "Jesus" | Poal: Say what you want.
This is why we can't have nice things anymore.
Shape them like Hurry-canes, for the elderly to enjoy.


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Womens winter down coat is available from many stores all across China at very cheap prices but the best deals are available from Taobao. However, it is hard to get them since importing from China is complex and one can easily end up losing their money if they do not go through an agent. That is where YOYBUY comes in. YOYBUY, in simple terms, helps English-speaking nations such as the USA, the UK and Australia to buy goods from China.
When you buy winterdowncoat through an agent, all you have to worry about is the marked price. The rest, that is, the custom duty and the choice of the carrier becomes the agent's worry. YOYBUY is a very reputable company. The Taobao broker also has a help center that is operational from 9am through 6pm China Standard Time. There is a handy cost calculator available from the home of Yoybuy.com to help you calculate the amount you will be spending for the goods you import.


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District education authority Bhakkar is giving job opportunity to the professional to enhance its functional skills. Authority wants to hire professional to run its operations and functions smoothly. If an organization has its staff compatible and skill full that organization make development by days and nights. Competent staff is the major tool and asset of any organization to meet its challenges and to complete their projects.
Number of Positions is 01. Academic criteria is Sixteen years education in computer Science, preferably in Software engendering, Information technology from HEC recognized university. There should be at least 05 years experience in relevant field.
Job description for this position is to preparation of concept papers for projects. Formulation of Planning Commission performs especially PC-IJI & IV for execution and completion of projects. Number of situations are 01. 16 years of education (preferably in economics, business management) or project management from HEC recognized university.
Number of position are 01. Job description of this position is to maintain accounts of this project. Responsible for all over the financial analysis of development projects. There required 16 years education in Finance, Accountancy, ACCA or CA and CMA.
Job description of this vacant position is active participation in determining feasibility of a project especially where construction is involved. Preparation of design/ RCEs of the planned projects.


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Home » Delete » How to Delete Snapchat Account?
How to Delete Snapchat Account?
Snapchat is a growing social media platform. It has become more popular among the young people and adults. It is used for the large corporations to promote products and provide coupons. As well as it is the fun and unique way to share the most significant and smallest moments with others. Once the app is installed, it permits the users to send informal messages and photos to their family members and friends.
If they open them, it will disappear after a few seconds. One can also post pictures or videos of their daily activities for anyone who follows. But all this will be disappeared after 24 hours. Recently, they introduced a tool to remove messages.
The Snapchat installation process is so easy. If a user wants to delete snapchat account permanently, they can follow the below-given steps. Removing the Snapchat from the device will save a lot of space and battery power.
It is highly recommended to download the data before deactivating the Snapchat. It is because the data includes account information, profile data, friends, search history, location, and login history. Once the account is deactivated your family members and friends will not be able to contact you on Snapchat.
Click on My data and submit a request.
It will email you a link once your data is ready to download.
When the link arrives follow it and download successfully.
HOW TO DELETE A SNAPCHAT ACCOUNT PERMANENTLY?
First, go to the https://support.snapchat.com/delete-account in any web browser from your desktop, mobile device, laptop or tablet.
Once opened, enter your Snapchat username and password in the given field.
Check the box to confirm that you are not a robot.
Click on Submit. The next page will appear.
Once again enter your password and username and click continue.
Select ‘delete my account’ at the bottom.
Once it is done, your Snapchat account will be terminated. Your friends will not be able to send you any snap further.
Open your browser and go to the Snapchat.com.
Scroll down and select ‘Support’ under the community section.
Select Learning the basics > Account settings > Delete an account.
Follow the same steps, which are mentioned in method 1.
Once you follow the above-mentioned methods your Snapchat account will be deleted permanently. Your friends will no longer be capable of sending you snap, and you won’t be able to log into the Snapchat without reactivating your account. Remember, you cannot reactivate or deactivate your Snapchat account whenever you want. It has a specific timeframe. Once you have deleted your account, it will take up to 30 days to reactivate your account.
© 2018 Wide4.com, All Right Reserved.


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As a busy mom of eleven, I have become the queen of finding the simplest ways to do seemingly difficult tasks. Homeschooling is one of them. Although the prospect of teaching multiple children may seem daunting to some, I have found a wonderful reprieve in using unit studies. Right now, I am using unit studies with all of my elementary age children, and it makes things so much easier.
Recently, after using the same Creation Science unit study for twelve weeks, my children and I grew bored with it, but, unfortunately, I didn’t have any other unit study curricula we hadn’t already used. After searching online for free unit studies, I became a little discouraged because the vast majority of them rely heavily on printable worksheets, and, while that may work for some, I knew my kids would quickly tire of those studies, as well.
Out of sheer desperation, I decided to write my own unit study, and, surprisingly, I really enjoyed it. I eventually ended up writing several, all of which I did end up using, and we thoroughly enjoyed them.
Today I’d like to share with you the very first unit study I wrote, “Famous Inventors/Inventing.” This study is meant to last approximately 2-3 weeks, but you can always have the option of shortening it or stretching it out as you see fit. I hope you enjoy it as much as we did!
A fair amount of time has passed since then, and my views on this homeschooling method have changed a bit. But first…let me tell you a little story.
John Holt, considered to be the Father of Unschooling is, by far, one of my favorite authors, and I find his ideas about the education of children to be altogether inspiring and quite beautiful. I discovered his books during a period in my life when I was experiencing some homeschool burnout and was looking for a more peaceful way for my children to learn at home.
Holt is a firm believer in a child’s natural ability to learn on their own, especially if they are freed from the trappings of conventional schooling. If a baby is able to learn to crawl, walk, and talk without any formal lessons, then it is only plausible that, if given the opportunity, a child can learn anything they value and deem necessary without any sort of outside coercion.
It was with these ideas in my head that I set out for us to become an unschooling family. Looking back, the first year of our “unschooling” endeavor was actually a bit more like relaxed homeschooling. We had some routines I was unwilling to let go of, such as family read-alouds, silent reading, and formal math curriculum. (Okay. Life of Fred. Not very formal but certainly more formal than most unschoolers would approve of.) Regardless, we were certainly doing less assigned work than we did in the past and much less than most other homeschoolers we knew, so, to me, we were unschoolers.
Eventually, I began to immerse myself in books and blogs about radical unschooling. As a Christian, some of their principles were quite alien and shocking to me, but I slowly began to fall for the blissful writings of these authors and figured that maybe if I let go of any structure at all, we would have this amazing, peaceful life where my children would be happily doing science experiments, reading great literature, and writing novels without any prompting from me.
At first, my children were elated. You mean we don’t even have to do math or listen to you read? Nope. Not even that.
I spent months waiting expectantly for my children to surprise me with ingenious inventions and innovative entrepreneurial ideas. It didn’t happen. Don’t get me wrong. There were certainly moments when one of my kids would astonish me with something particularly unexpected, such as when my daughter built a working candy machine out of Legos. But these moments were few and far between. A very large amount of time was being spent on nothing more than watching YouTube videos and bickering over whose turn it was on the phone.
I tried to be patient and kept repeating to myself, Just say yes more! Maybe they needed to deschool some more, or maybe I was failing to see the value in what they were doing.
It may have been either of these things, but once family relationships started suffering and our house turned into complete chaos, I finally gave in and admitted to myself that this just wasn’t working. This “blissful path” I set my hopes on was not what our family needed, and it was far from blissful.
I am not going to go so far as to say that unschooling never works. I’m sure it does for many people, but it clearly does not work for everyone.
Our family needs the structure that accompanies our homeschooling days. We need to know what is going to happen when, and it is such an advantage to have activities planned to keep my kids busy for a couple hours a day.
I am no longer the rigid homeschool mom I once was, but I’m also not willing to let my kids have total sovereignty over their education.
And think about it…do our kids deserve anything less?


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You know those guys who are really hooked on video games? Have the head gear, and talk to people on the Internet…sit in dark rooms playing games for hours? Welp, that’s pretty much me from March 15th through the beginning of April.
I will look like this.
I will spend the next several days on my couch. With my computer by my side. Two phones (no, I’m not a drug dealer… I just happen to have a work and a personal horn). Chatting to my friends on Gchat (you know who you are)… and watching hours upon hours of college hoops.
The thrill of the games. No matter how the season played out, as long as they make it into the tourney… the sky is the limit! Almost every single game is jam packed full of excitement.
Not to mention…. this very well might be my Alma mater, The Kentucky Wildcats’, year! I will be wearing my blue and white stripped socks for the next several weeks, just in case I just jinxed my team by writing this sentence.
So, in case you are wondering, this is what I’ll be up to for the days that follow.. my the odds be ever in your favor. Sorry, had to throw a little Hunger Games ref in there.
Cuse/Kentucky Final. Make it so.


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The first chick has made it through the first night and is doing well inspite of challenges along the way. Now it faces its second night with a new brother or sister!
And the new chick is new enough and still wet out of the egg that it will probably stay safely under the adult all night long.
But now as darkness falls, I do need to alert you to one thing....or even warn you about it.
I would guess that sometime tomorrow you will see a fight between the two chicks! A knock-down-drag-out fight!!
I have seen it almost every year that we have had two chicks.
It is hard to watch because it looks like they are going to kill each other. But in each of the instances I have observed it, both chicks have survived.
As best I can guess, I think it is what we so nonchalantly call "the pecking order". Although in this case it is literally the PECKING order.
I will maybe say something more about it in tomorrow morning's blog. But I wanted to give you a heads up so that it didn't shock you when you saw it.
So now we have the wonder of TWO LITTLE LOON CHICKS!!! How amazing is that?!?!


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For more information about GBHI or our programs, please contact us at info@gbhi.org.
Dominic Campbell, Atlantic Senior Fellow for Equity in Brain Health at GBHI was recently chosen as one of twelve of Next Avenue’s 2018 Influencers in Aging.
Eleonore Bayen one of our first Atlantic Fellows recently had a paper published in the Journal of Medical Internet Research.
The Lancet recently published an article highlighting the diverse, inter-professional character of our program and profiling some of our fellows.
While I was writing my PhD I craved the opportunity to discuss and debate the state of the dementia field, where it’s been and where it’s going and the often competing priorities of stakeholders including people living with dementia, families, health care professionals, researchers, policy makers and the charity sector. What I learned was that a PhD was often a long, lonely slog with only the warm glow from my computer screen to keep me company.
But for the past nine months, I’ve finally had that opportunity to discuss and debate and I’ve gotten to experience it in a multi-disciplinary setting to better understand the perspectives of other disciplines different to my own.
After 20 years of marriage, after raising two kids, after building a farm and tending horses and dogs, Caroline knew this much about the man she loves: he is tender-hearted, fun-loving and never lets stress land too long on his shoulders. Four years ago, the old Nick somehow morphed into a new guy, one who is not so patient. A guy who lost his social edge and seems unable to read faces. He is tired and withdrawn. “He’s just not the same guy,” she says. “I want him back."
The man falls out of the bed. It breaks. This is not the first bed to drop under the weight of his flailing bones and thrashing limbs. The bed is now braced by a two-by-four, and it is only a matter of time before it will go down. His balance is poor and he falls out of the bed. This happens all the time. It is not his fault that he has destroyed three beds, two couches, countless toilets seats and an array of nearby furniture. He crashes and trips into things. His body outwits his mind. It throws him around, shamelessly.


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#1 Favorite Movie of Your Life!
Too fat for a buffet?
Has there been any sight of Wingman since Katrina?
Is Wingman really Ramah in disguise?
we know where you're at, but where are you from?

industry_corpus2: Film & Entertainment


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If God or the Supreme Being is He, She or It; residing in heaven, up there in the sky or just omnipresent in the known or unknown universe. Do we need to indulge in this debate? Not really. Rather we create our own god based on noble thoughts, ethics, and good karma.
Basically, it is an eloquent temperament we are trying to build which gives rationality and practicality to the institution of God.
The ecumenical concept of God of being the supreme governor who creates, sustains, and destroys the universe, and everything else including what influences our lives, does not reveal the reasons behind all the puzzles and mysteries of His or Her observable deeds.
In other words, our perception of God as being a creator with His mystical powers which sustains the universe, can not comprehend many universal and natural phenomenon.
One reason is that man is just one of the millions of creatures who is microscopic in His infinite and colossal universe. Still, our imaginations and metaphysical attempts know no boundaries to fathom His magnanimity. For a moment let us compare a human being to a small ant who is trying to study God up there in the celestial world.
Philosophers, saints, scientists, and even common man have all tried to study God and came up with varied perceptions and explanations. Imagination is very basic part of human psychology.
However, these discernments seldom explain what role God plays or His reasons of our happiness, sorrows, and everything else we come across in our day to day lives. We see, face or endure tragedies around us every day in this world of turmoil. And then ask God ‘why’.
In this endeavor by mobilizing rational and moral thinking we are creating those karmas which can rationally explain the cause or causes of events personally experienced by us or happening around us where God may be involved or maybe not.
We are the major players to generate events and thus know the reasons for their results. Nevertheless, we can leave unexplained experiences as part of His mysterious ‘lila’ or play.
We are told, to be honest, humble, and sincere, be considerate and helpful to others, be merciful, forget and forgive, love fellow beings and care for the environments, including animals, plants, and nature. And everything else which is pious, pure, and morally firm to bring us closer to God realization.


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There are 6 United States Postal Service post boxes available to the public in Beech Creek, PA. You can use any one of these locations to mail your letter or small package. For additional collection boxes in neighboring communities, see the list of post boxes in Pennsylvania.
Are you looking for a post office? See the list of post offices in Beech Creek, PA.


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JEHMAD, INC. is an entity registered at California with company number C0680949. Company is incorporated on 16th May 1973. Current status of the company is DISSOLVED.
Do you know this company? Do you have positive or negative experience with JEHMAD, INC.? Rate the company and help other users.


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Rice pudding isn't just for kids! This grown-up version gets a brilliant crust of caramelised sugar to add an extra texture to an otherwise creamy and unctuous pudding. A caramelised sugar topping takes rice pudding from creamy to dreamy.
1. Place the rice, almond milk, water and salt in a medium saucepan on a medium heat. Bring to a simmer, then stir over a low heat for 45 minutes, stirring all the time and keeping a watchful eye over it.
2. Divide the rice pudding between four heat-resistant bowls or ramekins. Sprinkle the tops with the sugar.
3. Grab your blowtorch, or if you don't have one a blowtorch turn your grill to its hottest setting. Torch the top of the rice pudding until golden or place the ramekins on a baking tray and place under the preheated grill to caramelise.
4. Top with berries and serve.


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Swaziland is a small kingdom surrounded entirely by Mozambique and South Africa. The proximity to, and close business ties with, South Africa are clearly a boon to Swaziland’s economy, as the US$3,3034 GDP per capita statistic is 5 times that found in Mozambique. By comparison, neighboring South Africa had a per capita income of US$6,617 in 2013.
Swaziland’s main business language is English, which is the country’s second official language after Swati. This helps to facilitate trade with South Africa, in which English is the primary business language despite being the fourth most popular of 8 official languages. This also brings with it the potential to do business with the many other countries around the globe that prefer to conduct business in English.
Another major facilitator of trade between the two countries is that they are part of the world’s oldest customs union, which also includes Botswana, Lesotho and Namibia. This means that goods can pass freely between the two nations without additional tax costs, opening up the import/export market and making Swaziland a useful low-cost processing centre for South African goods and raw materials. Without this trade agreement, it would be much costlier for the landlocked Swaziland to procure goods from abroad, as well as to transport its domestic products internationally.
Swaziland’s economic growth tends to follow the direction of South Africa’s economy.
Since 1995, GDP growth in these two economies has had a correlation coefficient of 0.34, with that correlation reducing to approximately 0.1 from 1970. The fortunes of these two nations have clearly become more closely intertwined as time has passed. Although this correlation is far from perfect, the differences can likely be attributed to the relative size and international exposure of the South African market, while Swaziland’s economy is more reliant on regional trade. Even so, the absolute direction of the two markets’ growth was the same in 8 out of the 19 years sampled above, or 42% of the time.
The Heritage Foundation’s 2015 report on economic freedom estimates that Swaziland received US$67million of FDI inflows, accounting for less than 2% of the country’s 2013 GDP. These low investment levels are explained to some extent by the difficulty of doing business in Swaziland, with the World Bank relegating the Kingdom from 102nd to 105th on its Ease of Doing Business Index for 2016.
Swaziland fares even more poorly when it comes to starting a business, falling from 146th to 156th for that category on the same ranking.
To learn more about how to invest in Swaziland as a foreigner, visit our website or contact Healy Consultants Group PLC’ experts at .
Image credit: Swaziland landscape” by Sara Atkins – originally posted to Flickr as Swaziland. Licensed under CC BY 2.0 via Commons.

industry_corpus2: Finance & Economics


text: Your support now is more vital than ever. War on Want will continue fighting inequality, injustice and human rights violations around the world. Thank you for any donation you can make today.


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A classic brunch recipe, this bagel will be a big hit.
Toast the bagels. Spread each half with cream cheese and top with smoked salmon. Sprinkle with capers and serve.


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It was speaking to me. I loved it. I loved the fact that it was handmade. I loved the fact that even though it had a couple of coats of paint, the inside was left natural. I loved the fact that it had history.
This old medicine cabinet was a barn find during a recent trip to Pennsylvania. I'm not even sure the owners knew they still had it. When I pulled it out from under a table and asked them how much they were asking for the piece they looked very confused. Maybe they were just wonderring why I wanted it. It was $1. SCORE!!!! Here it is, in all it's painted up dirty glory.
The first layer of paint was turquoise and then a second layer of a pinkish peach paint covered that and then add some dirt and spider webs.
Check out the inside. Never painted! The back is made from old tongue and groove beadboard.
My husband was with me when I spotted this and I think even he wasn't sure what I would do with it, but I had a plan.
First things first, the cabinet received a good scrubbing. Then I proceeded to remove the old hinges.
Unfortunately, they had a couple layers of paint on them also and were a bit of a challenge to remove. Eventually I was able to get them off. Then I soaked them in paint remover. I wanted to reuse them and was hoping they would have an aged look after the paint was gone.
With the hinges removed, I was able to separate the door and the main part of the cabinet. The next step was to give both pieces a good sanding, then I could proceed with my vision.
I painted the edges of both pieces black.
I did this in hopes that when I painted the entire piece white and distressed it, the black edges would show. It kindof worked.
This took about four coats of red paint to get a solid colored cross. I distressed the cross a little too.
Now, onto the main part of the cabinet. First, I cleaned it again and then gave it a coat of danish oil to help protect the natural wood.
Back to the old hinges. After removing them from the paint remover and rinsing them really well, I used a wire brush and was able to remove all of the paint from them and the screws. They looked aged and I was thrilled that I was going to be able to use the original hinges again.
I screwed the new, old hinges to the cabinet and the door. Once it was put back together I sealed the outside of the cabinet with a protective clear matte sealer.
I'm more in love now. My husband was even a little impressed with the transformation. If only I could show the original owners in Pennsylvania. I think they'd be pleased that their cabinet has found a new life. What do you think?
You did such a great job with this medicine cabinet Adina! Love it!
that is great. I would love to make one of those out of an old cabinet door. I love to recycle.
What a great idea. I love the red cross on it.
This turned out great. I bet they were confused...probably thought no one would want it, so they left it under that table...until you came along.
This is used to secure dressings made to the wound.
Used in cleaning wounds and washing out foreign bodies.
This is used for reducing the risk of infection in abrasions or other wounds.
This is used in cutting materials for dressing or flesh itself.
This is used for sanitizing equipments or broken skin.
This is used in measuring the body temperature of the affected individual.
This is used In applying medications and cleaning of wounds.
Primarily used for pains and also serves as an antiplatelet.
This is used to reduce pains and some include paracetamol, panadol.
Burns could result when the cosmetologist or their clients mishandles a hot equipment such as the blow dryer.
The seriousness of the burn depends on the amount of burnt surface area, body part burnt and age of the victim.
• Use a wet soft cloth to cool the area.
• Continue with cooling the affected area to relieve the burning sensation.
• Remove any tightening material, most importantly those around the burnt area.
• Then continue with dressing up the burnt area.


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A flip project will generally be taxed as ordinary income that is subject to the investor’s marginal tax rate. This is because a flip is classified as a “dealer” and is deemed to be in an active trade or business.
A long-term rental is defined as passive income and is subject to the passive activity rules. These rules allow you to offset passive income against passive losses. Any resulting net passive income will be taxed at ordinary income tax rates. In addition, upon the sale or disposition of a rental property, capital gains (or losses) will be generated that will be classified at a preferable long term capital gains rates.

industry_corpus2: Real Estate & Construction


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This fantastic company is currently looking to appoint an experienced HR Business Partner to work predominantly within the Hampshire area, this will however also include travel to London, Coventry and various other locations within the south on an as and when basis.
The purpose of the role is to work alongside line managers to implement and embed the strategic HR agenda, providing HR expertise to the business, and addressing all associated people matters in accordance with best practice methodology, internal compliance and legal requirements.
Provide input into the line of business people strategy, implement and embed across business area of responsibility, along with business unit and divisional strategic HR initiatives.
Act as champion in communicating and embedding HR strategy, initiatives, policies and procedures across business area of responsibility, business unit or division.
Accountable for influencing positive employee relations within business area of responsibility to maintain and improve business output requirements and ensure increased employee engagement.
Act as champion in developing and maintaining positive relationships with line managers, business unit/divisional specialists, trade unions and administrative shared services etc.
Accountable for supporting line managers in disciplinary, grievance and welfare casework across business area of responsibility.
The ideal candidate for this role will have significant generalist HR experience with previous track record of delivering significant contribution to business strategy.
- Proven track record of delivering significant contribution to business strategy, and to implementing and embedding HR strategies in large and complex organisations. Success when working on multiple projects.
- Considerable experience in supporting line managers in disciplinary, grievance and welfare case management and in preparing and presenting at employment tribunals, and in developing line management capability in same.
- Demonstrable experience of providing HR support to acquisitions, business tenders and managing the transition of people in and out of a business according to TUPE legislation.
- Experience in employee relations matters and establishing and developing relationships with Trade Unions for ongoing positive interactions.
- Demonstrable evidence of developing and sustaining positive working relationships at a line management level including the ability to negotiate and influence.
- Up to date knowledge of employment law, CIPD would be desirable.


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Lying just off the bustling Rambla, this tiny, triangular place is one of Barcelona's oldest bars. It was opened in 1933 by Miguel Boadas, who learnt his trade at the famous Floridita bar in Cuba.
Miguel passed away in 1967 and his famous bar is now owned by his daughter, Maria Dolores Boadas. She has altered little of her inheritance and her father's memorabilia still adorns the paneled walls. Maria was born the year after her father opened this bar and until recent years and ill-health was practically part of the furniture.
The jolly team of bartenders resplendent in black jackets, white shirts and black bow ties ply their trade with confidence and mix drinks by flamboyantly pouring the ingredients from one shaker held aloft into another several feet below.
Cocktails are wonderfully old-school and Dry Martinis, Gimlets and Mojitos appear most popular. Martinis come frozen with little dilution. Try one of their excellent Daiquiris or the 'Cocktail del Dia' (cocktail of the day) chalked on a board behind the bar.